دورية أكاديمية
أعرض في EDS

Passive accumulation of alkaloids in non-toxic frogs challenges paradigms of the origins of acquired chemical defenses.

التفاصيل البيبلوغرافية
العنوان: Passive accumulation of alkaloids in non-toxic frogs challenges paradigms of the origins of acquired chemical defenses.
المؤلفون: Tarvin RD; Museum of Vertebrate Zoology and Department of Integrative Biology, University of California, Berkeley, Berkeley, CA 94720 USA., Coleman JL; Department of Integrative Biology and Biodiversity Collections, University of Texas at Austin, Austin, TX 78712 USA.; Smithsonian Tropical Research Institute, Balboa, Ancón, Republic of Panama., Donoso DA; Grupo de Investigación en Ecología Evolutiva en los Trópicos (EETROP), Universidad de las Américas, Quito, Ecuador.; Ecological Networks Lab, Technische Universität Darmstadt, Darmstadt, Germany., Betancourth-Cundar M; Departamento de Ciencias Biológicas, Universidad de los Andes, Bogotá, Colombia, 111711., López-Hervas K; Max Planck Institute for Evolutionary Biology, Plön, Germany 24306., Gleason KS; Department of Chemistry and Physics, Indiana State University, Terre Haute, IN 47809, USA., Sanders JR; Department of Chemistry and Physics, Indiana State University, Terre Haute, IN 47809, USA., Smith JM; Department of Chemistry and Physics, Indiana State University, Terre Haute, IN 47809, USA., Ron SR; Museo de Zoología, Escuela de Biología, Facultad de Ciencias Exactas y Naturales, Pontificia Universidad Católica del Ecuador, Quito, Ecuador., Santos JC; Department of Biological Sciences, St John's University, NY, USA 11439., Sedio BE; Department of Integrative Biology and Biodiversity Collections, University of Texas at Austin, Austin, TX 78712 USA.; Smithsonian Tropical Research Institute, Balboa, Ancón, Republic of Panama., Cannatella DC; Department of Integrative Biology and Biodiversity Collections, University of Texas at Austin, Austin, TX 78712 USA., Fitch R; Department of Chemistry and Physics, Indiana State University, Terre Haute, IN 47809, USA.
المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jun 03. Date of Electronic Publication: 2024 Jun 03.
نوع المنشور: Journal Article; Preprint
اللغة: English
بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
مستخلص: Understanding the origins of novel, complex phenotypes is a major goal in evolutionary biology. Poison frogs of the family Dendrobatidae have evolved the novel ability to acquire alkaloids from their diet for chemical defense at least three times. However, taxon sampling for alkaloids has been biased towards colorful species, without similar attention paid to inconspicuous ones that are often assumed to be undefended. As a result, our understanding of how chemical defense evolved in this group is incomplete. Here we provide new data showing that, in contrast to previous studies, species from each undefended poison frog clade have measurable yet low amounts of alkaloids. We confirm that undefended dendrobatids regularly consume mites and ants, which are known sources of alkaloids. Further, we confirm the presence of alkaloids in two putatively non-toxic frogs from other families. Our data suggest the existence of a phenotypic intermediate between toxin consumption and sequestration-passive accumulation-that differs from active sequestration in that it involves no derived forms of transport and storage mechanisms yet results in low levels of toxin accumulation. We discuss the concept of passive accumulation and its potential role in the origin of chemical defenses in poison frogs and other toxin-sequestering organisms.
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معلومات مُعتمدة: R35 GM150574 United States GM NIGMS NIH HHS
فهرسة مساهمة: Keywords: adaptive landscape; bioaccumulation; novelty; toxicokinetics; toxin resistance; toxin sequestration
تواريخ الأحداث: Date Created: 20240527 Latest Revision: 20240629
رمز التحديث: 20240629
مُعرف محوري في PubMed: PMC11118485
DOI: 10.1101/2024.05.13.593697
PMID: 38798461
قاعدة البيانات: MEDLINE
الوصف
تدمد:2692-8205
DOI:10.1101/2024.05.13.593697