دورية أكاديمية
Suppression of anthracnose disease by orsellinaldehyde isolated from the mushroom Coprinus comatus.
| العنوان: | Suppression of anthracnose disease by orsellinaldehyde isolated from the mushroom Coprinus comatus. |
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| المؤلفون: | Cabutaje EM; The United Graduate School of Agricultural Sciences, Tottori University, Tottori 680-8553, Japan., Ueno K; Faculty of Agriculture, Tottori University, 4-101, Koyama-cho Minami, Tottori 680-8553, Japan., Dela Cruz TEE; Department of Biological Sciences, College of Science, University of Santo Tomas, España Blvd. 1015, Manila, Philippines., Ishihara A; Faculty of Agriculture, Tottori University, 4-101, Koyama-cho Minami, Tottori 680-8553, Japan.; International Platform for Dryland Research and Education, Tottori University, 1390 Hamasaka, Tottori 680-0001, Japan. |
| المصدر: | Journal of applied microbiology [J Appl Microbiol] 2024 Jun 03; Vol. 135 (6). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: England NLM ID: 9706280 Publication Model: Print Cited Medium: Internet ISSN: 1365-2672 (Electronic) Linking ISSN: 13645072 NLM ISO Abbreviation: J Appl Microbiol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2022- : Oxford : Oxford University Press Original Publication: Oxford : Published for the Society for Applied Bacteriology by Blackwell Science, c1997- |
| مواضيع طبية MeSH: | Colletotrichum*/drug effects , Plant Diseases*/microbiology , Plant Diseases*/prevention & control , Coprinus*, Benzaldehydes/pharmacology ; Antifungal Agents/pharmacology ; Fungicides, Industrial/pharmacology ; Spores, Fungal/drug effects |
| مستخلص: | Aims: Anthracnose caused by Colletotrichum species is one of the most devastating diseases of fruits and crops. We isolated and identified an antifungal compound from the mushroom Coprinus comatus and investigated its inhibitory potential against anthracnose disease-causing fungi with the goal of discovering natural products that can suppress anthracnose-caused plant disease. Methods and Results: The culture filtrate of C. comatus was subjected to a bioassay-guided isolation of antifungal compounds. The active compound was identified as orsellinaldehyde (2,4-dihydroxy-6-methylbenzaldehyde) based on mass spectroscopy and nuclear magnetic resonance analyses. Orsellinaldehyde displayed broad-spectrum inhibitory activity against different plant pathogenic fungi. Among the tested Colletotrichum species, it exhibited the lowest IC50 values on conidial germination and germ tube elongation of Colletotrichum orbiculare. The compound also showed remarkable inhibitory activity against Colletotrichum gloeosporiodes. The staining of Colletotrichum conidia with fluorescein diacetate and propidium iodide demonstrated that the compound is fungicidal. The postharvest in-vivo detached fruit assay indicated that orsellinaldehyde suppressed anthracnose lesion symptoms on mango and cucumber fruits caused by C. gloeosporioides and C. orbiculare, respectively. Conclusions: Orsellinaldehyde was identified as a potent antifungal compound from the culture filtrate of C. comatus. The inhibitory and fungicidal activities of orsellinaldehyde against different Colletotrichum species indicate its potential as a fungicide for protecting various fruits against anthracnose disease-causing fungi. (© The Author(s) 2024. Published by Oxford University Press on behalf of Applied Microbiology International.) |
| فهرسة مساهمة: | Keywords: anthracnose; antifungal compound; colletotrichum species; mushroom; orsellinaldehyde; plant pathogenic fungi |
| المشرفين على المادة: | 0 (Benzaldehydes) 0 (Antifungal Agents) 0 (Fungicides, Industrial) |
| تواريخ الأحداث: | Date Created: 20240527 Date Completed: 20240605 Latest Revision: 20240605 |
| رمز التحديث: | 20240605 |
| DOI: | 10.1093/jambio/lxae128 |
| PMID: | 38802124 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1365-2672 |
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| DOI: | 10.1093/jambio/lxae128 |