دورية أكاديمية
أعرض في EDS

Sexual health in adult survivors of childhood cancer: A Project REACH study.

التفاصيل البيبلوغرافية
العنوان: Sexual health in adult survivors of childhood cancer: A Project REACH study.
المؤلفون: Chevalier LL; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.; Department of Psychosocial Oncology and Palliative Care, Dana-Farber Cancer Institute, Boston, USA.; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA., McCormick K; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Cooney TM; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Recklitis CJ; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA., Bober SL; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.; Department of Psychosocial Oncology and Palliative Care, Dana-Farber Cancer Institute, Boston, USA.; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.
المصدر: Cancer [Cancer] 2024 Sep 01; Vol. 130 (17), pp. 3023-3033. Date of Electronic Publication: 2024 May 28.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 0374236 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0142 (Electronic) Linking ISSN: 0008543X NLM ISO Abbreviation: Cancer Subsets: MEDLINE
أسماء مطبوعة: Publication: <2005- >: Hoboken, NJ : Wiley
Original Publication: New York [etc.] Published for the American Cancer Society by J. Wiley [etc.]
مواضيع طبية MeSH: Cancer Survivors*/statistics & numerical data , Sexual Health* , Sexual Dysfunction, Physiological*/epidemiology , Sexual Dysfunction, Physiological*/etiology, Humans ; Adult ; Female ; Male ; Middle Aged ; Adolescent ; Young Adult ; Prospective Studies ; Aged ; Neoplasms/complications ; Neoplasms/therapy ; Sexual Dysfunctions, Psychological/epidemiology ; Sexual Dysfunctions, Psychological/etiology ; Child
مستخلص: Background: Sexual dysfunction is a significant complication of treatment for many adult-onset cancers. However, comparatively less is known about sexual dysfunction in adult childhood cancer survivors (CCSs). Research has been limited by the exclusion of specific cancers (e.g., central nervous system [CNS] tumors) and the lack of validated measures, which makes it difficult to understand the nature and prevalence of sexual dysfunction in CCSs.
Methods: A total of 249 adult CCSs (aged 18-65 years) enrolled in Project REACH, a prospective cohort study, and completed measures of physical and mental health, including sexual dysfunction. Participants scoring ≤19 on the Female Sexual Function Index 6 or ≤21 on the International Index of Erectile Function 5 were classified as experiencing sexual dysfunction. Analyses examined the relationships between sexual dysfunction and demographic, disease, treatment, and health variables.
Results: A total of 78 participants (32%) experienced clinically significant sexual dysfunction. In univariate analysis, sexual dysfunction was significantly associated with CNS tumor diagnosis (odds ratio [OR], 2.56) and surgery (OR, 1.96) as well as with health variables such as fatigue (OR, 3.00), poor sleep (OR, 2.84), pain (OR, 2.04), depression (OR, 2.64), poor physical health (OR, 2.45), and poor mental health (OR, 2.21). Adjusted analyses found that CNS tumor diagnosis (p = .001) and health variables (p = .025) contribute significantly to sexual dysfunction in CCSs.
Conclusions: Approximately one third of adult CCSs report clinically significant sexual dysfunction, which underscores a significant screening and treatment need. However, because available measures were developed for survivors of adult cancers, research to create a sexual health measure specifically for adult CCSs is necessary to better identify the sexual health concerns of this vulnerable population.
(© 2024 American Cancer Society.)
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معلومات مُعتمدة: Swim Across America
فهرسة مساهمة: Keywords: central nervous system tumors; childhood cancer survivors; mental health; physical health; sexual dysfunction
تواريخ الأحداث: Date Created: 20240528 Date Completed: 20240808 Latest Revision: 20240808
رمز التحديث: 20240809
DOI: 10.1002/cncr.35363
PMID: 38804691
قاعدة البيانات: MEDLINE
الوصف
تدمد:1097-0142
DOI:10.1002/cncr.35363