دورية أكاديمية
The UK clinical eye research strategy: refreshing research priorities for clinical eye research in the UK.
| العنوان: | The UK clinical eye research strategy: refreshing research priorities for clinical eye research in the UK. |
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| المؤلفون: | Bourne RRA; Vision and Eye Research Institute, School of Medicine, Anglia Ruskin University, Cambridge, UK. rb@rupertbourne.co.uk.; Department of Ophthalmology, Cambridge University Hospitals, Cambridge, UK. rb@rupertbourne.co.uk., Moledina M; Imperial College NHS Foundation Trust, London, UK., Azuara-Blanco A; Centre for Public Health, Queen's University Belfast, Belfast, UK., Saleh GM; Research, Cataract and Adnexal Dept, Moorfields Eye Hospital, London, UK., Self JE; University of Southampton, Southampton, UK., Sivaprasad S; NIHR Moorfields Clinical Research Facility, Moorfields Eye Hospital, London, UK., Sharma SM; Dept of Ophthalmology, Oxford Eye Hospital, Oxford University Hospitals NHS Trust, Oxford, UK., Ross A; Department of Ophthalmology, Cambridge University Hospitals, Cambridge, UK.; Aswan University Hospital, Aswan, Egypt., Gilbert RM; Department of Ophthalmology, Cambridge University Hospitals, Cambridge, UK., Abdalla Elsayed MEA; Dept of Ophthalmology, Oxford Eye Hospital, Oxford University Hospitals NHS Trust, Oxford, UK., Moon WY; Dept of Ophthalmology, Oxford Eye Hospital, Oxford University Hospitals NHS Trust, Oxford, UK., Doug M; Vision and Eye Research Institute, School of Medicine, Anglia Ruskin University, Cambridge, UK., Mulholland PJ; NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.; Centre for Optometry & Vision Sciences, School of Biomedical Sciences, Ulster University, Coleraine, Northern Ireland, UK., Day AC; NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK., Romano V; Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy., Hoad GV; Macular Society, Andover, UK., Kara M; Fight for Sight, London, UK., Murray A; Moorfields Eye Charity, Moorfields Eye Hospital, London, UK., Gow L; Eye care and living well services, Royal National Institute of Blind people, London, UK., Ghanchi F; Bradford Teaching Hospitals, Royal Infirmary, Bradford, West Yorkshire, UK., Patel PJ; NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK., Gale RP; York Hospital, University of York, York, UK., Dinah C; Department of Ophthalmology, London North West University Healthcare NHS Trust, London, UK.; Brain Sciences, Imperial College London, London, UK., Valentine K; Fight for Sight, London, UK., Yelf C; Macular Society, Andover, UK., Poustie V; NIHR Clinical Research Network, University of Liverpool, Liverpool, UK. |
| مؤلفون مشاركون: | NIHR Ophthalmology Specialty Group, Executive Group of UK Clinical Eye Research Strategy |
| المصدر: | Eye (London, England) [Eye (Lond)] 2024 Jul; Vol. 38 (10), pp. 1947-1957. Date of Electronic Publication: 2024 May 29. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8703986 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5454 (Electronic) Linking ISSN: 0950222X NLM ISO Abbreviation: Eye (Lond) Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2003->: London : Nature Publishing Group Original Publication: [London : Ophthalmological Society of the United Kingdom, 1987- |
| مواضيع طبية MeSH: | Ophthalmology*/organization & administration , Biomedical Research*, Humans ; United Kingdom ; Female ; Male ; Middle Aged ; Eye Diseases/therapy ; Eye Diseases/diagnosis ; Surveys and Questionnaires ; Health Priorities ; Adult ; Aged |
| مستخلص: | Objectives: To validate and update the 2013 James Lind Alliance (JLA) Sight Loss and Vision Priority Setting Partnership (PSP)'s research priorities for Ophthalmology, as part of the UK Clinical Eye Research Strategy. Methods: Twelve ophthalmology research themes were identified from the JLA report. They were allocated to five Clinical Study Groups of diverse stakeholders who reviewed the top 10 research priorities for each theme. Using an online survey (April 2021-February 2023), respondents were invited to complete one or more of nine subspecialty surveys. Respondents indicated which of the research questions they considered important and subsequently ranked them. Results: In total, 2240 people responded to the survey (mean age, 59.3 years), from across the UK. 68.1% were female. 68.2% were patients, 22.3% healthcare professionals or vision researchers, 7.1% carers, and 2.1% were charity support workers. Highest ranked questions by subspecialty: Cataract (prevention), Cornea (improving microbial keratitis treatment), Optometric (impact of integration of ophthalmic primary and secondary care via community optometric care pathways), Refractive (factors influencing development and/or progression of refractive error), Childhood onset (improving early detection of visual disorders), Glaucoma (effective and improved treatments), Neuro-ophthalmology (improvements in prevention, diagnosis and treatment of neurodegeneration affecting vision), Retina (improving prevention, diagnosis and treatment of dry age-related macular degeneration), Uveitis (effective treatments for ocular and orbital inflammatory diseases). Conclusions: A decade after the initial PSP, the results refocus the most important research questions for each subspecialty, and prime targeted research proposals within Ophthalmology, a chronically underfunded specialty given the substantial burden of disability caused by eye disease. (© 2024. The Author(s).) |
| References: | BMJ Open. 2014 Jul 23;4(7):e004905. (PMID: 25056971) Eye (Lond). 2019 Apr;33(4):610-618. (PMID: 30459469) Lancet Glob Health. 2021 Feb;9(2):e144-e160. (PMID: 33275949) Br J Ophthalmol. 2024 Feb 20;:. (PMID: 37923373) |
| معلومات مُعتمدة: | United Kingdom WT_ Wellcome Trust; N/A Fight for Sight UK; N/A Macular Society |
| فهرسة مساهمة: | Investigator: E Ansari; NAV Beare; RRA Bourne; E Chambers; F Cordeiro; S De Silva; S Downes; R Gale; F Ganchi; C Hammond; GV Hoad; J Jackson; A King; AJ Lotery; P Mulholland; I Nickson; P Patel; FJ Rowe; GM Saleh; P Scanlon; B Shah; J Silvestri; V Sung; A Tatham; M Ugarte; D Varma; M Vortruba; S Waseem; AA Blanco; M Bowen; C Bunce; N Caplin; R Crosby; A Ghareeb; R Gomes; K Hanna; GV Hoad; T Houlihan; L Low; JE Self; SM Sharma |
| تواريخ الأحداث: | Date Created: 20240528 Date Completed: 20240705 Latest Revision: 20240708 |
| رمز التحديث: | 20240708 |
| مُعرف محوري في PubMed: | PMC11226710 |
| DOI: | 10.1038/s41433-024-03049-6 |
| PMID: | 38806699 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1476-5454 |
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| DOI: | 10.1038/s41433-024-03049-6 |