Usefulness of minimally invasive autopsy in the diagnosis of arboviruses to increase the sensitivity of the Epidemiological Surveillance System in Ceará, Brazil.

التفاصيل البيبلوغرافية
العنوان:	Usefulness of minimally invasive autopsy in the diagnosis of arboviruses to increase the sensitivity of the Epidemiological Surveillance System in Ceará, Brazil.
المؤلفون:	Almeida LM; Centro Universitário Christus, Faculdade de Medicina, Fortaleza, CE, Brazil., Melo DN; Universidade Federal do Ceará, Programa de Pós-Graduação em Patologia, Fortaleza, CE, Brazil., Silva MMD; Centro Universitário Christus, Faculdade de Medicina, Fortaleza, CE, Brazil., Souza PMM; Secretaria da Saúde do Estado do Ceará, Serviço de Verificação de Óbito Dr. Rocha Furtado, Fortaleza, CE, Brazil., Silva FKS; Universidade Federal do Ceará, Ambulatório de Pesquisa Clínica Replick, Fortaleza, CE, Brazil., Coelho TMS; Secretaria da Saúde do Estado do Ceará, Fortaleza, CE, Brazil., Lima STS; Laboratório Central de Saúde Pública do Ceará, Fortaleza, CE, Brazil., Mota AGM; Secretaria da Saúde do Estado do Ceará, Serviço de Verificação de Óbito Dr. Rocha Furtado, Fortaleza, CE, Brazil., Monteiro RAA; Universidade de São Paulo, Faculdade de Medicina de São Paulo, São Paulo, SP, Brazil., Saldiva PHN; Universidade de São Paulo, Faculdade de Medicina de São Paulo, São Paulo, SP, Brazil., Oliveira GGS; Fundação Oswaldo Cruz, Centro Gonçalo Moniz, Salvador, BA, Brazil., Cavalcanti LPG; Universidade Federal do Ceará, Programa de Pós-Graduação em Saúde Coletiva, Fortaleza, CE, Brazil.
المصدر:	Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil [Epidemiol Serv Saude] 2024 May 24; Vol. 33, pp. e2024008. Date of Electronic Publication: 2024 May 24 (Print Publication: 2024).
نوع المنشور:	Journal Article; Case Reports
اللغة:	English; Portuguese
بيانات الدورية:	Publisher: Secretaria de Vigilância em Saúde e Ambiente - Ministério da Saúde do Brasil Country of Publication: Brazil NLM ID: 101248287 Publication Model: eCollection Cited Medium: Internet ISSN: 2237-9622 (Electronic) Linking ISSN: 16794974 NLM ISO Abbreviation: Epidemiol Serv Saude Subsets: MEDLINE
أسماء مطبوعة:	Publication: Brasília, DF : Secretaria de Vigilância em Saúde e Ambiente - Ministério da Saúde do Brasil Original Publication: Brasília, DF : Secretaria de Vigilância em Saúde do Ministério da Saúde, 2003-
مواضيع طبية MeSH:	Autopsy/methods , Arbovirus Infections/epidemiology , Arbovirus Infections/diagnosis , Arbovirus Infections/pathology, Humans ; Brazil/epidemiology ; Female ; Sensitivity and Specificity ; Male ; Middle Aged ; Adult ; Adolescent ; Young Adult ; Arboviruses/isolation & purification ; Aged ; Population Surveillance/methods ; Epidemiological Monitoring ; Cause of Death ; Child ; Child, Preschool
مستخلص:	Objective: To create a protocol for performing minimally invasive autopsies (MIA) in detecting deaths from arboviruses and report preliminary data from its application in Ceará state, Brazil. Methods: Training was provided to medical pathologists on MIA. Results: A protocol was established for performing MIA, defining criteria for sample collection, storage methods, and diagnoses to be carried out according to the type of biological sample; 43 MIAs were performed in three months. Of these, 21 (48.8%) arrived at the Death Verification Service (SVO) with arboviruses as a diagnostic hypothesis, and seven (16.3%) were confirmed (six chikungunya cases and one dengue case); cases of COVID-19 (n = 9), tuberculosis (n = 5), meningitis (n = 4), cryptococcosis (n = 1), Creutzfeldt-Jakob disease (n = 1), breast cancer (n = 1), and human rabies (n = 1) were also confirmed. Conclusion: The protocol implemented enabled identification of a larger number of suspected arbovirus-related deaths, as well as confirmation of other diseases of interest for surveillance. Main Results: A protocol was developed to perform minimally invasive autopsies (MIAs) in Death Verification Services (SVO), capable of expanding the system's capacity to identify a greater number of deaths suspected to be due to arboviruses. Implications for Services: The experience suggests that in-service trained health professionals are able to perform MIA, and that use of this technique in SVOs has been shown to be capable of increasing the system's sensitivity in detecting deaths of interest to public health. Perspectives: Trained professionals will be able to collect biological material in hospitals, through MIA, in cases of interest for health surveillance and when family members do not allow a complete conventional autopsy to be performed.
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تواريخ الأحداث:	Date Created: 20240529 Date Completed: 20240529 Latest Revision: 20240621
رمز التحديث:	20240621
مُعرف محوري في PubMed:	PMC11131572
DOI:	10.1590/S2237-96222024V33E2024008.en
PMID:	38808901
قاعدة البيانات:	MEDLINE

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تدمد:	2237-9622
DOI:	10.1590/S2237-96222024V33E2024008.en