دورية أكاديمية

Phenotyping chronic respiratory diseases with airways obstruction.

التفاصيل البيبلوغرافية
العنوان: Phenotyping chronic respiratory diseases with airways obstruction.
المؤلفون: Nguyen TC; Polyclinic, Department of Family Medicine, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam., Tran HVT; Polyclinic, Department of Family Medicine, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam., Tran MHT; Polyclinic, Department of Family Medicine, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam., Godin I; School of Public Health, Université Libre de Bruxelles (ULB), Brussels, Belgium., Michel O; Centre Hospitalier Universitaire Brugmann, ULB, Brussels, Belgium.
المصدر: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease [Int J Tuberc Lung Dis] 2024 Jun 01; Vol. 28 (6), pp. 287-294.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: The Union Country of Publication: France NLM ID: 9706389 Publication Model: Print Cited Medium: Internet ISSN: 1815-7920 (Electronic) Linking ISSN: 10273719 NLM ISO Abbreviation: Int J Tuberc Lung Dis Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Paris, France : The Union, c1997-
مواضيع طبية MeSH: Pulmonary Disease, Chronic Obstructive*/epidemiology , Pulmonary Disease, Chronic Obstructive*/diagnosis , Phenotype* , Asthma*/epidemiology , Asthma*/diagnosis, Humans ; Middle Aged ; Male ; Female ; Prevalence ; Adult ; Vietnam/epidemiology ; Aged ; Skin Tests ; Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome/epidemiology ; Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome/diagnosis
مستخلص:

BACKGROUND

Given the high prevalence of asthma-chronic obstructive pulmonary disease overlap (ACO) in Vietnam, there is an urgent need to establish a simplified strategy for categorising patients as either having asthma or chronic obstructive pulmonary disease (COPD). This classification would streamline the application of treatment recommendations outlined by the Global Initiative for Asthma (GINA) and the Global Initiative for Chronic Obstructive Lung Disease (GOLD).

METHODS

Patients with obstructive lung function were classified as having COPD, asthma, or ACO based on GINA/GOLD guidelines. We hypothesised that ACO-like asthma (ACO-A) would present with positive skin prick tests (SPTs) or early onset of symptoms without a history of tuberculosis (TB), while those with ACO-like COPD (ACO-B) would exhibit negative SPTs and late onset of symptoms and/or a history of TB.

RESULTS

Among 235 patients, the prevalence of asthma, ACO-A, ACO-B, and COPD was respectively 21%, 22%, 17%, and 40%. Allergic history, rhinitis, and childhood asthma were associated with ACO-A, while high cumulative smoking was correlated with ACO-B. Socio-economic and demographic parameters, medical history, clinical features, smoking habits, lung function, and para-clinical investigations significantly differed between "all asthma" (i.e., individuals with asthma combined with ACO-A) and "all COPD" (i.e., individuals with COPD combined with ACO-B).

CONCLUSION

Based on SPTs, history of TB, and onset age, ACO patients may be defined as people with asthma or COPD.
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تواريخ الأحداث: Date Created: 20240601 Date Completed: 20240601 Latest Revision: 20240601
رمز التحديث: 20240602
DOI: 10.5588/ijtld.23.0383
PMID: 38822484
قاعدة البيانات: MEDLINE
الوصف
تدمد:1815-7920
DOI:10.5588/ijtld.23.0383