دورية أكاديمية
Developmental toxicity of the neonicotinoid pesticide clothianidin to the larvae of the crustacean Decapoda, Penaeus vannamei.
| العنوان: | Developmental toxicity of the neonicotinoid pesticide clothianidin to the larvae of the crustacean Decapoda, Penaeus vannamei. |
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| المؤلفون: | Luo Z; School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China; School of Marine Biology and Fisheries, Hainan University, Haikou, Hainan 570228, China., Lin ZY; School of Marine Biology and Fisheries, Hainan University, Haikou, Hainan 570228, China., Li ZF; School of Marine Biology and Fisheries, Hainan University, Haikou, Hainan 570228, China., Fu ZQ; School of Marine Science, Sun Yat-sen University, Zhuhai, Guangdong 519082, China., Han FL; School of Marine Biology and Fisheries, Hainan University, Haikou, Hainan 570228, China., Li EC; School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China. Electronic address: ecli@bio.ecnu.edu.cn. |
| المصدر: | Journal of hazardous materials [J Hazard Mater] 2024 Aug 05; Vol. 474, pp. 134787. Date of Electronic Publication: 2024 May 31. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9422688 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3336 (Electronic) Linking ISSN: 03043894 NLM ISO Abbreviation: J Hazard Mater Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Amsterdam : Elsevier, |
| مواضيع طبية MeSH: | Larva*/drug effects , Neonicotinoids*/toxicity , Guanidines*/toxicity , Thiazoles*/toxicity , Insecticides*/toxicity , Penaeidae*/drug effects , Penaeidae*/growth & development, Animals ; Water Pollutants, Chemical/toxicity ; Apoptosis/drug effects |
| مستخلص: | The developmental toxicity effects of neonicotinoid pesticides such as clothianidin have not been fully explored in agricultural applications. This is particularly noteworthy because such pesticides significantly impact the survival rates of invertebrates, with arthropod larvae being particularly vulnerable. This study aimed to address this research gap by specifically investigating the toxicological effects of clothianidin on the developmental stages of the larvae of the economically important aquaculture species Penaeus vannamei. In these experiments, shrimp eggs were exposed to seawater containing different concentrations of clothianidin beginning at N1, and each phase was observed and analyzed to determine its toxic impact on larval development. These results revealed that clothianidin induces an increase in deformity rates and triggers abnormal cell apoptosis. It also significantly reduced survival rates and markedly decreased body length and heart rate in the later stages of larval development (P3). Transcriptomic analysis revealed disruptions in larval DNA integrity, protein synthesis, and signal transduction caused by clothianidin. To survive prolonged exposure, larvae may attempt to maintain their viability by repairing cell structures and enhancing signal transduction mechanisms. This study offers the first empirical evidence of the toxicity of clothianidin to arthropod larvae, underscoring the impact of environmental pollution on aquatic health. Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2024 Elsevier B.V. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Developmental toxicity; Mechanism; Neonicotinoid insecticides; Shrimp larvae |
| المشرفين على المادة: | 2V9906ABKQ (clothianidin) 0 (Neonicotinoids) 0 (Guanidines) 0 (Thiazoles) 0 (Insecticides) 0 (Water Pollutants, Chemical) |
| تواريخ الأحداث: | Date Created: 20240601 Date Completed: 20240625 Latest Revision: 20240625 |
| رمز التحديث: | 20240625 |
| DOI: | 10.1016/j.jhazmat.2024.134787 |
| PMID: | 38823101 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1873-3336 |
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| DOI: | 10.1016/j.jhazmat.2024.134787 |