دورية أكاديمية

Patterns of oxytocin use for induction and augmentation of labour among healthcare providers in Nigeria.

التفاصيل البيبلوغرافية
العنوان: Patterns of oxytocin use for induction and augmentation of labour among healthcare providers in Nigeria.
المؤلفون: Ejekam CS; Advanced Centre of Excellence of Drug Research, Herbal Medicine Development and Regulatory Science (ACEDHARS), University of Lagos, Akoka, Lagos, Nigeria. Chioma.s.ejekam@gmail.com., Okafor IP; Department of Community Health and Primary Care, College of Medicine, University of Lagos, Idiaraba Lagos, Nigeria., Okunade KS; Department of Obstetrics and Gynaecology, College of Medicine, University of Lagos, Idiaraba Lagos, Nigeria., Igbokwe U; Solina Centre for International Development and Research, Libreville Street, Wuse II, Abuja, Nigeria., Nwokike J; Promoting the Quality of Medicines Program Plus, U.S Pharmacopeia, Twinbrook Rockville, MD, USA.
المصدر: BMC pregnancy and childbirth [BMC Pregnancy Childbirth] 2024 Jun 01; Vol. 24 (1), pp. 403. Date of Electronic Publication: 2024 Jun 01.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100967799 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2393 (Electronic) Linking ISSN: 14712393 NLM ISO Abbreviation: BMC Pregnancy Childbirth Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, [2001-
مواضيع طبية MeSH: Oxytocin*/administration & dosage , Labor, Induced*/methods , Labor, Induced*/statistics & numerical data , Oxytocics*/administration & dosage , Health Personnel*/statistics & numerical data, Humans ; Nigeria ; Female ; Pregnancy ; Cross-Sectional Studies ; Adult ; Practice Patterns, Physicians'/statistics & numerical data ; Surveys and Questionnaires ; Labor, Obstetric ; Male ; Young Adult
مستخلص: Background: The practice of intrapartum use of oxytocin for induction and augmentation of labour is increasing worldwide with documented wide variations in clinical use, especially dose administrations. There is also evidence of intrapartum use by unauthorized cadre of staff.
Aim: This study assessed the patterns - frequency of intrapartum use of oxytocin, the doses and routes of administration for induction and augmentation of labour, and identified the predictors of oxytocin use for induction and augmentation of labour by healthcare providers in Nigeria.
Methods: This was a cross-sectional study conducted among healthcare providers - doctors, nurses/midwives and community health workers (CHWs) in public and private healthcare facilities across the country's six geopolitical zones. A multistage sampling technique was used to select 6,299 eligible healthcare providers who use oxytocin for pregnant women during labour and delivery. A self-administered questionnaire was used to collect relevant data and analysed using STATA 17 statistical software. Summary and inferential statistics were done and further analyses using multivariable regression models were performed to ascertain independent predictor variables of correct patterns of intrapartum oxytocin usage. The p-value was set at < 0.05.
Results: Of the 6299 respondents who participated in the study, 1179 (18.7%), 3362 (53.4%), and 1758 (27.9%) were doctors, nurses/midwives and CHWs, respectively. Among the respondents, 4200 (66.7%) use oxytocin for augmentation of labour while 3314 (52.6%) use it for induction of labour. Of the 1758 CHWs, 37.8% and 49% use oxytocin for induction and augmentation of labour, respectively. About 10% of the respondents who use oxytocin for the induction or augmentation of labour incorrectly use the intramuscular route of administration and about 8% incorrectly use intravenous push. Being a doctor, and a healthcare provider from government health facilities were independent positive predictors of the administration of correct dose oxytocin for induction and augmentation of labour. The CHWs were most likely to use the wrong route and dose administration of oxytocin for the induction and augmentation of labour.
Conclusion: Our study unveiled a concerning clinical practice of intrapartum oxytocin use by healthcare providers in Nigeria - prevalence of intrapartum use of oxytocin, inappropriate routes of administration for induction and augmentation of labour, varied and inappropriately high start dose of administration including unauthorized and high intrapartum use of oxytocin among CHWs.
(© 2024. The Author(s).)
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فهرسة مساهمة: Keywords: Augmentation of labour; Healthcare providers; Induction of labour; Intrapartum oxytocin use; Nigeria; Patterns of oxytocin use
المشرفين على المادة: 50-56-6 (Oxytocin)
0 (Oxytocics)
تواريخ الأحداث: Date Created: 20240602 Date Completed: 20240602 Latest Revision: 20240604
رمز التحديث: 20240604
مُعرف محوري في PubMed: PMC11144308
DOI: 10.1186/s12884-024-06593-x
PMID: 38824569
قاعدة البيانات: MEDLINE
الوصف
تدمد:1471-2393
DOI:10.1186/s12884-024-06593-x