دورية أكاديمية
Ehrlichia spp. infection worsens cardiac damage in dogs with canine visceral leishmaniasis.
| العنوان: | Ehrlichia spp. infection worsens cardiac damage in dogs with canine visceral leishmaniasis. |
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| المؤلفون: | Zanfagnini LG; Universidade Federal do Acre - UFAC, Rio Branco, AC, Brasil., Reis Junior JL; Departamento de Medicina Veterinária, Universidade Federal de Juiz de Fora - UFJF, Juiz de Fora, MG, Brasil., Rocha VN; Departamento de Medicina Veterinária, Universidade Federal de Juiz de Fora - UFJF, Juiz de Fora, MG, Brasil., Souza SF; Universidade Federal do Acre - UFAC, Rio Branco, AC, Brasil., Hitara KY; Departamento de Medicina Veterinária, Universidade Federal de Juiz de Fora - UFJF, Juiz de Fora, MG, Brasil., Marcondes M; Universidade Estadual Paulista - UNESP, Araçatuba, SP, Brasil., Pacheco AD; Universidade Federal do Acre - UFAC, Rio Branco, AC, Brasil. |
| المصدر: | Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria [Rev Bras Parasitol Vet] 2024 May 31; Vol. 33 (2), pp. e018223. Date of Electronic Publication: 2024 May 31 (Print Publication: 2024). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Colégio Brasileiro de Parasitologia Veterinária Country of Publication: Brazil NLM ID: 9440482 Publication Model: eCollection Cited Medium: Internet ISSN: 1984-2961 (Electronic) Linking ISSN: 0103846X NLM ISO Abbreviation: Rev Bras Parasitol Vet Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: São Paulo, Brasil : Colégio Brasileiro de Parasitologia Veterinária, [1992]- |
| مواضيع طبية MeSH: | Leishmaniasis, Visceral*/veterinary , Leishmaniasis, Visceral*/complications , Leishmaniasis, Visceral*/diagnosis , Dog Diseases*/parasitology , Dog Diseases*/microbiology , Ehrlichiosis*/veterinary , Ehrlichiosis*/complications , Ehrlichiosis*/diagnosis, Animals ; Dogs ; Male ; Coinfection/veterinary ; Female ; Myocarditis/veterinary ; Myocarditis/microbiology ; Myocarditis/parasitology ; Ehrlichia/isolation & purification ; Myocardium/pathology |
| مستخلص: | In endemic areas for canine visceral leishmaniasis (CVL), the occurrence of coinfection with other pathogens, such as Ehrlichia spp., has been associated with worsening of the clinical condition. The study aimed to evaluate the occurrence of histological changes in the myocardia of dogs naturally infected with Leishmania chagasi with or without coinfection with Ehrlichia spp.. We evaluated paraffin-embedded myocardial sections from 31 dogs, affected by either L. chagasi alone or coinfected with L. chagasi and Ehrlichia spp., to compare the extent and degree of cardiac damage. The blocks were divided into two groups. G1 (dogs infected only by L. chagasi) and G2 (dogs coinfected with L. chagasi and Ehrlichia spp.). The right atrium free wall, right ventricle free wall, left ventricle, and interventricular septum of all groups were evaluated. Cardiac alterations were observed in 41.93% (52/124) of the fragments evaluated and inflammatory infiltrate was the most common pattern found. The G2 group showed a higher incidence of myocarditis, with 61.53% (32/52), compared to the G1 group, in which 20 out of 72 cases (27.7%) exhibited histopathological changes (p <0.05). These findings confirmed that coinfection can potentiate cardiac damage in dogs. |
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| تواريخ الأحداث: | Date Created: 20240605 Date Completed: 20240605 Latest Revision: 20240719 |
| رمز التحديث: | 20240719 |
| مُعرف محوري في PubMed: | PMC11253817 |
| DOI: | 10.1590/S1984-29612024023 |
| PMID: | 38836809 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1984-2961 |
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| DOI: | 10.1590/S1984-29612024023 |