دورية أكاديمية
أعرض في EDS

Hypoglobus, Exophthalmos, and Interpupillary Distance: Measuring Globe Dystopia in Thyroid Eye Disease.

التفاصيل البيبلوغرافية
العنوان: Hypoglobus, Exophthalmos, and Interpupillary Distance: Measuring Globe Dystopia in Thyroid Eye Disease.
المؤلفون: Saffari PS; David Geffen School of Medicine, University of California, Los Angeles., Nesemann J; Department of Ophthalmology, Francis I Proctor Foundation, University of California, San Francisco, San Francisco., Katsev B; University of California, Los Angeles, Los Angeles., Palileo BMU; Riverside School of Medicine, University of California, Riverside, CA., Yeganeh A; Northeast Ohio Medical University, Rootstown, OH., Mustak H; Division of Ophthalmology, University of Cape Town, Cape Town, South Africa., Wang Y; Institute of Orbital Diseases, The General Hospital of the Armed Police Force, Beijing, China., Rootman DB; Doheny and Stein Eye Institutes, Division of Orbital and Oculoplastic Surgery, University of California, Los Angeles, Los Angeles, CA.
المصدر: The Journal of craniofacial surgery [J Craniofac Surg] 2024 Jul-Aug 01; Vol. 35 (5), pp. 1329-1333. Date of Electronic Publication: 2024 Jun 03.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9010410 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-3732 (Electronic) Linking ISSN: 10492275 NLM ISO Abbreviation: J Craniofac Surg Subsets: MEDLINE
أسماء مطبوعة: Publication: <2014-> : Hagerstown, MD : Lippincott Williams & Wilkins
Original Publication: Burlington, Ont. : B.C. Decker, c1990-
مواضيع طبية MeSH: Decompression, Surgical* , Exophthalmos*/surgery , Graves Ophthalmopathy*/surgery, Humans ; Female ; Male ; Cross-Sectional Studies ; Middle Aged ; Adult ; Aged ; Orbit/surgery ; Orbit/diagnostic imaging
مستخلص: Purpose: Thyroid eye disease (TED) is characterized by a variety of disfiguring periocular changes. Vertical globe changes affecting the relative position of the eyelids are not well understood in patients with TED. This study seeks to determine the effect of orbital decompression on vertical globe displacement in patients with TED, without TED, and with intraconal tumor (ICT).
Methods: For this cross-sectional study, a clinical database was used to identify patients with TED. Comparison groups were drawn from separate anonymized databases. Vertical position and interpupillary distance (IPD) were measured from photographs and exophthalmos was measured via Hertel's exophthalmometer. Primary outcomes were vertical globe position at baseline and postoperatively in patients with TED and ICT. Secondary outcomes included the relationship between vertical globe position, exophthalmos, and IPD.
Results: Among 269 participants meeting the inclusion criteria, mean vertical globe position was significantly lower in patients with TED following lateral decompression surgery compared to controls, after accounting for race, age, and sex. While patients with ICT had a significant difference in preoperative and postoperative IPD, patients with TED did not. Medial or inferior decompression did not significantly change globe position and lateral decompression did not cause lateral canthal dystopia in patients with TED. No association between postoperative changes in exophthalmometry, IPD, and globe position was found in patients with TED.
Conclusions: Patients with TED experience hypoglobus that does not improve following decompression surgery. There was no correlation between change in vertical globe position and exophthalmos or IPD among patients with TED. Surgeons should discuss the possibility of hypoglobus as a persistent finding for patients with TED undergoing decompression surgery.
Competing Interests: D.B.R. is a consultant for Horizon Therapeutics. The remaining authors report no conflicts of interest.
(Copyright © 2024 by Mutaz B. Habal, MD.)
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تواريخ الأحداث: Date Created: 20240605 Date Completed: 20240723 Latest Revision: 20240723
رمز التحديث: 20240723
DOI: 10.1097/SCS.0000000000010345
PMID: 38838355
قاعدة البيانات: MEDLINE
الوصف
تدمد:1536-3732
DOI:10.1097/SCS.0000000000010345