دورية أكاديمية

Prevalence of somatic symptoms among Ebola Virus Disease (EVD) survivors in Africa: a systematic review and meta-analysis.

التفاصيل البيبلوغرافية
العنوان: Prevalence of somatic symptoms among Ebola Virus Disease (EVD) survivors in Africa: a systematic review and meta-analysis.
المؤلفون: Mandizadza OO; School of Public Health, Zhejiang Chinese Medical University, Hangzhou, China., Phebeni RT; Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Ji C; School of Public Health, Zhejiang Chinese Medical University, Hangzhou, China. jchi2005@126.com.
المصدر: BMC public health [BMC Public Health] 2024 Jun 05; Vol. 24 (1), pp. 1511. Date of Electronic Publication: 2024 Jun 05.
نوع المنشور: Journal Article; Systematic Review; Meta-Analysis
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100968562 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2458 (Electronic) Linking ISSN: 14712458 NLM ISO Abbreviation: BMC Public Health Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, [2001-
مواضيع طبية MeSH: Hemorrhagic Fever, Ebola*/epidemiology , Survivors*/statistics & numerical data , Survivors*/psychology, Humans ; Prevalence ; Medically Unexplained Symptoms ; Arthralgia/epidemiology ; Headache/epidemiology ; Africa, Western/epidemiology ; Fatigue/epidemiology ; Africa/epidemiology
مستخلص: Background: Many Ebola virus disease (EVD) survivors have reported somatic and neuropsychological symptoms after discharge from the Ebola Treatment Unit (ETU). Since the 2014-2016 Ebola epidemic in West Africa, various studies have investigated and identified these symptoms. Evidence on somatic symptoms is widely available in the literature, however, there is no concise overview of the prevalence across different time intervals.
Methods: This meta-analysis was conducted following the (PRISMA) guidelines. A database search was conducted to identify original studies that reported the prevalence of symptoms. The primary outcome measure was the prevalence rate of several somatic symptoms. Results were pooled, and prevalence rates were assessed over time, to elucidate any particular trends.
Results: We included 23 studies (5,714 participants). The pooled prevalence was: arthralgia 50% (95% CI: 41%-59%); headache 44% (95% CI: 36%-52%); myalgia 32% (95% CI: 26%-38%); abdominal pain 27% (95% CI: 15%-39%); fatigue 25% (95% CI: 19%-31%); numbness of feet 16% (95% CI: 14%-18%); numbness of hands 12% (95% CI: 10%-14%) and hearing loss 9% (95% CI: 5%-12%). Prevalence across different time intervals revealed significant patterns. All the symptoms persisted for more than 2 years after discharge except for abdominal pain.
Conclusion: The pooled prevalence rates of somatic symptoms are notably high. Arthralgia and headache are the most prevalent of the symptoms, with hearing loss and numbness in hands and feet being the least. We found that arthralgia, myalgia, and abdominal pain decreased over time. However, headache, fatigue, numbness of hands and feet, and hearing loss increased over time.
(© 2024. The Author(s).)
References: PLOS Glob Public Health. 2022;2(10):. (PMID: 36382340)
Lancet Infect Dis. 2022 Aug;22(8):1163-1171. (PMID: 35588755)
BMC Pediatr. 2021 Oct 30;21(1):482. (PMID: 34717580)
Travel Med Infect Dis. 2017 Jul - Aug;18:18-23. (PMID: 28478336)
Virulence. 2021 Dec;12(1):885-901. (PMID: 33734027)
Rheumatology (Oxford). 2017 Dec 1;56(12):2068-2072. (PMID: 28371810)
Lancet Infect Dis. 2016 Mar;16(3):331-8. (PMID: 26725449)
Neuropsychiatr Dis Treat. 2022 Oct 05;18:2229-2237. (PMID: 36221293)
Anesth Analg. 2015 Sep;121(3):798-809. (PMID: 26287303)
PLoS Negl Trop Dis. 2018 Aug 2;12(8):e0006580. (PMID: 30071016)
Lancet. 2016 Jul 30;388(10043):498-503. (PMID: 27209148)
Emerg Infect Dis. 2016 Jan;22(1):150-2. (PMID: 26690042)
N Engl J Med. 2014 Dec 18;371(25):2402-9. (PMID: 25390460)
Am J Ophthalmol. 2017 Mar;175:114-121. (PMID: 27998698)
Microbiol Spectr. 2016 Jun;4(3):. (PMID: 27337474)
BMJ. 2012 Jan 03;344:d7762. (PMID: 22214758)
Bull World Health Organ. 1978;56(2):271-93. (PMID: 307456)
BMJ. 2021 Mar 29;372:n71. (PMID: 33782057)
Curr Infect Dis Rep. 2017 May;19(5):19. (PMID: 28391498)
Int J Clin Pract. 2009 Oct;63(10):1426-34. (PMID: 19769699)
Biomed Res Int. 2018 Jun 28;2018:1909410. (PMID: 30050920)
BMC Public Health. 2021 Nov 11;21(1):2066. (PMID: 34763704)
N Engl J Med. 2015 Dec 17;373(25):2484-6. (PMID: 26672870)
J Infect Dis. 1999 Feb;179 Suppl 1:S28-35. (PMID: 9988162)
Clin Infect Dis. 2015 Oct 1;61(7):1035-42. (PMID: 26060289)
Front Public Health. 2016 Jul 04;4:142. (PMID: 27458576)
Clin Infect Dis. 2016 Jun 1;62(11):1360-1366. (PMID: 27001797)
Int J Epidemiol. 2008 Oct;37(5):1148-57. (PMID: 18424475)
Evid Based Ment Health. 2014 Feb;17(1):30. (PMID: 24477535)
Arch Public Health. 2014 Nov 10;72(1):39. (PMID: 25810908)
Emerg Infect Dis. 2016 Apr;22(4):641-6. (PMID: 26983037)
PLoS One. 2019 Sep 27;14(9):e0223068. (PMID: 31560708)
Clin Infect Dis. 2020 Oct 23;71(7):1749-1755. (PMID: 31693114)
Nat Commun. 2020 Jul 24;11(1):3730. (PMID: 32709840)
Ophthalmology. 2017 Feb;124(2):170-177. (PMID: 27914832)
Clin Infect Dis. 2021 Sep 15;73(6):1046-1054. (PMID: 33822010)
N Engl J Med. 2019 Mar 7;380(10):924-934. (PMID: 30855742)
Oncotarget. 2017 Feb 21;8(8):12784-12791. (PMID: 28061463)
Lancet Infect Dis. 2016 Jun;16(6):e82-e91. (PMID: 27020309)
Expert Rev Anti Infect Ther. 2015;13(10):1185-7. (PMID: 26293407)
Lancet Infect Dis. 2015 Aug;15(8):905-12. (PMID: 25910637)
Clin Infect Dis. 2016 Jan 1;62(1):125-6. (PMID: 26349549)
Clin Infect Dis. 2023 Feb 8;76(3):e835-e840. (PMID: 36065768)
Open Forum Infect Dis. 2018 Sep 21;5(10):ofy239. (PMID: 30386807)
Campbell Syst Rev. 2022 Mar 27;18(2):e1230. (PMID: 36911350)
Clin Infect Dis. 2019 Apr 8;68(8):1388-1393. (PMID: 30107392)
J Epidemiol Community Health. 2013 Nov 1;67(11):974-8. (PMID: 23963506)
PLoS Negl Trop Dis. 2022 Oct 31;16(10):e0010889. (PMID: 36315609)
Commun Biol. 2022 Nov 9;5(1):1204. (PMID: 36352100)
Eur J Clin Microbiol Infect Dis. 2017 Nov;36(11):2193-2200. (PMID: 28695354)
فهرسة مساهمة: Keywords: Ebola Virus Disease (EVD); Meta-analysis; Somatic symptoms; Survivors; Systematic Review
تواريخ الأحداث: Date Created: 20240605 Date Completed: 20240606 Latest Revision: 20240709
رمز التحديث: 20240709
مُعرف محوري في PubMed: PMC11155043
DOI: 10.1186/s12889-024-19013-8
PMID: 38840082
قاعدة البيانات: MEDLINE
الوصف
تدمد:1471-2458
DOI:10.1186/s12889-024-19013-8