دورية أكاديمية
Effects of age on microvascular function in patients with normal coronary arteries.
العنوان: | Effects of age on microvascular function in patients with normal coronary arteries. |
---|---|
المؤلفون: | Jansen TPJ; Department of Cardiology, Radboud University Medical Centre, Nijmegen, the Netherlands., Crooijmans C; Department of Cardiology, Radboud University Medical Centre, Nijmegen, the Netherlands., Pijls N; Department of Cardiology, Maasstad Hospital, Rotterdam, the Netherlands., Paradies V; Department of Cardiology, Maasstad Hospital, Rotterdam, the Netherlands., de Vos A; Department of Cardiology, Catharina Hospital, Eindhoven, the Netherlands., Dimitriu-Leen AC; Department of Cardiology, Radboud University Medical Centre, Nijmegen, the Netherlands., Elias-Smale S; Department of Cardiology, Radboud University Medical Centre, Nijmegen, the Netherlands., Rodwell L; Department of Health Evidence, Section Biostatistics, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, the Netherlands., van Royen N; Department of Cardiology, Radboud University Medical Centre, Nijmegen, the Netherlands., Smits P; Department of Cardiology, Maasstad Hospital, Rotterdam, the Netherlands., Damman P; Department of Cardiology, Radboud University Medical Centre, Nijmegen, the Netherlands. |
المصدر: | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology [EuroIntervention] 2024 Jun 03; Vol. 20 (11), pp. e690-e698. Date of Electronic Publication: 2024 Jun 03. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Société Europa édition Country of Publication: France NLM ID: 101251040 Publication Model: Electronic Cited Medium: Internet ISSN: 1969-6213 (Electronic) Linking ISSN: 1774024X NLM ISO Abbreviation: EuroIntervention Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Toulouse : Société Europa édition, c2005- |
مواضيع طبية MeSH: | Microcirculation* , Coronary Vessels*/physiopathology , Coronary Vessels*/diagnostic imaging , Coronary Circulation*/physiology , Vascular Resistance*/physiology, Humans ; Middle Aged ; Male ; Female ; Aged ; Adult ; Age Factors ; Young Adult ; Coronary Artery Disease/physiopathology ; Angina Pectoris/physiopathology |
مستخلص: | Background: It has been suggested that coronary microvascular function decreases with age, irrespective of the presence of epicardial atherosclerosis. Aims: Our aim is to quantitatively investigate the effects of age on microvascular function in patients with normal coronary arteries. Methods: In 314 patients with angina with no obstructive coronary artery disease (ANOCA), microcirculatory function was tested using the continuous thermodilution method. In 305 patients, the association between age and both resting and hyperaemic myocardial blood flow (Q), microvascular resistance (R Results: The mean age was 59±9 years with a range from 22 to 79 years. The mean resting Q (Q Conclusions: There is an age-dependent physiological increase in minimal microvascular resistance and decrease in microvascular function, which is represented by a decreased MRR and is independent of atherosclerosis. The age-dependent decrease in MRR was present in both patients with and without CMD and was most evident in patients with smooth coronary arteries. |
References: | J Am Coll Cardiol. 2021 Oct 5;78(14):1471-1479. (PMID: 34593129) Eur Heart J. 2023 Aug 7;44(30):2862-2869. (PMID: 37350567) J Nucl Med. 1995 Nov;36(11):2032-6. (PMID: 7472593) JACC Cardiovasc Interv. 2020 Jan 13;13(1):20-29. (PMID: 31918939) Catheter Cardiovasc Interv. 2004 May;62(1):56-63. (PMID: 15103605) EuroIntervention. 2021 Oct 20;17(9):757-764. (PMID: 33720019) JACC Cardiovasc Interv. 2018 Oct 22;11(20):2044-2054. (PMID: 30268877) J Am Coll Cardiol. 2021 Oct 12;78(15):1541-1549. (PMID: 34620412) EuroIntervention. 2023 Jun 05;19(2):e155-e166. (PMID: 36809253) Eur Heart J. 2022 Apr 19;43(16):1582-1593. (PMID: 34849697) Int J Cardiol. 2023 May 15;379:1-8. (PMID: 36863419) Microcirculation. 2016 Feb;23(2):157-67. (PMID: 26661273) J Am Coll Cardiol. 2019 Feb 19;73(6):684-693. (PMID: 30765035) Catheter Cardiovasc Interv. 2022 Dec;100(7):1195-1205. (PMID: 36273417) J Am Coll Cardiol. 2021 Feb 16;77(6):728-741. (PMID: 33573743) Circulation. 1993 Jul;88(1):62-9. (PMID: 8319357) Heart Vessels. 2020 Dec;35(12):1633-1639. (PMID: 32524236) Front Cardiovasc Med. 2021 Oct 14;8:750071. (PMID: 34722680) Cardiovasc Res. 1974 Jul;8(4):526-33. (PMID: 4609611) JACC Cardiovasc Interv. 2021 Mar 22;14(6):595-605. (PMID: 33736767) Int J Cardiol. 2021 Jun 15;333:14-20. (PMID: 33711394) JACC Cardiovasc Interv. 2023 Apr 10;16(7):872-874. (PMID: 36898940) JACC Cardiovasc Interv. 2023 Feb 27;16(4):470-481. (PMID: 36858668) EuroIntervention. 2016 Aug 20;12(6):701-7. (PMID: 27542781) J Am Heart Assoc. 2023 Aug 15;12(16):e030480. (PMID: 37577948) |
تواريخ الأحداث: | Date Created: 20240606 Date Completed: 20240606 Latest Revision: 20240608 |
رمز التحديث: | 20240608 |
مُعرف محوري في PubMed: | PMC11145310 |
DOI: | 10.4244/EIJ-D-23-00778 |
PMID: | 38840575 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1969-6213 |
---|---|
DOI: | 10.4244/EIJ-D-23-00778 |