دورية أكاديمية
أعرض في EDS

Proactive consultation of laboratory medicine increased diagnostic rate of multiple myeloma: One single center's 12-year experience.

التفاصيل البيبلوغرافية
العنوان: Proactive consultation of laboratory medicine increased diagnostic rate of multiple myeloma: One single center's 12-year experience.
المؤلفون: Chang CC; Department of Clinical Pathology, Far Eastern Memorial Hospital, New Taipei, Taiwan.; Department of Nursing, Cardinal Tien Junior College of Healthcare and Management, Yilan, Taiwan., Ho JL; Department of Clinical Pathology, Far Eastern Memorial Hospital, New Taipei, Taiwan., Lin PC; Department of Clinical Pathology, Far Eastern Memorial Hospital, New Taipei, Taiwan., Lin CP; Department of Clinical Pathology, Far Eastern Memorial Hospital, New Taipei, Taiwan., Tsai WT; Department of Clinical Pathology, Far Eastern Memorial Hospital, New Taipei, Taiwan., Huang HL; Department of Clinical Pathology, Far Eastern Memorial Hospital, New Taipei, Taiwan., Yu YB; Department of Internal Medicine, Division of Oncology and Hematology, Far Eastern Memorial Hospital, New Taipei, Taiwan.; Faculty of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Graduate Institute of Medicine, Yuan Ze University, Taoyuan, Taiwan., Chen WC; Department of Nursing, Cardinal Tien Junior College of Healthcare and Management, Yilan, Taiwan.; Public Health Bureau, New Taipei, Taiwan., Chu FY; Department of Clinical Pathology, Far Eastern Memorial Hospital, New Taipei, Taiwan.; Graduate School of Biotechnology and Bioengineering, Yuan Ze University, Taoyuan, Taiwan.; Department of Medical Laboratory Science and Biotechnology, Yuanpei University, Hsinchu, Taiwan.
المصدر: Medicine [Medicine (Baltimore)] 2024 Jun 07; Vol. 103 (23), pp. e38523.
نوع المنشور: Journal Article; Observational Study
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Hagerstown, Md : Lippincott Williams & Wilkins
مواضيع طبية MeSH: Multiple Myeloma*/diagnosis , Multiple Myeloma*/mortality , Referral and Consultation*/statistics & numerical data , Delayed Diagnosis*/statistics & numerical data, Humans ; Male ; Female ; Retrospective Studies ; Middle Aged ; Aged ; Adult ; Algorithms
مستخلص: Multiple myeloma (MM) was one of the hardest cancers to diagnose because of numerous nonspecific symptoms, leading to diagnostic delay. Proactive consultation of laboratory medicine (PCLM) could help timely diagnosis of blood cancers, avoiding diagnostic delay. This study aimed to evaluate the effect of PCLM on diagnosis and outcomes in MM. This retrospective study was conducted in newly diagnosed MM patients from 2011 to 2022. Implementation of PCLM initiated in 2015 with a laboratory-oriented algorithm. The annual diagnostic rate, patient demographics, the time intervals from symptom onset to diagnosis and to treatment, and clinical outcomes were analyzed. A total of 134 patients were newly diagnosed during the study interval. The diagnostic rate increased from 4.65 ± 1.59 to 7.43 ± 1.52 per million patient-visits after implementation of PCLM. The median time interval from symptom onset to diagnosis was significantly shortened after implementation of PCLM (50 days with interquartile range [IQR]: 24-136 days vs 150 days with IQR: 41-385 days, P = .003). Besides, the 1-year survival was significantly higher in patients diagnosed as MM after implementation of PCLM (72.4% vs 51.7%, P = .035). Implementation of PCLM not only increased diagnostic rate of MM and improved outcomes, but also raise awareness for MM and promote multidisciplinary collaboration in healthcare.
Competing Interests: The authors have no funding and conflicts of interest to disclose.
(Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.)
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تواريخ الأحداث: Date Created: 20240607 Date Completed: 20240607 Latest Revision: 20240609
رمز التحديث: 20240609
مُعرف محوري في PubMed: PMC11155562
DOI: 10.1097/MD.0000000000038523
PMID: 38847713
قاعدة البيانات: MEDLINE
الوصف
تدمد:1536-5964
DOI:10.1097/MD.0000000000038523