التفاصيل البيبلوغرافية
| العنوان: |
The Risk of Virus Emergence in South America: A Subtle Balance Between Increasingly Favorable Conditions and a Protective Environment. |
| المؤلفون: |
de Thoisy B; 1Laboratoire des Interactions Virus-Hôtes, Institut Pasteur de la Guyane, Cayenne, French Guiana., Gräf T; 2Laboratório de Virologia Molecular, Instituto Carlos Chagas/Fiocruz PR, Curitiba, Brazil; email: claudia.dossantos@fiocruz.br., Mansur DS; 3Laboratório de Imunobiologia, Departamento de Microbiologia, Imunologia, e Parasitologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Santa Catarina, Brazil., Delfraro A; 4Sección Virología, Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay., Dos Santos CND; 2Laboratório de Virologia Molecular, Instituto Carlos Chagas/Fiocruz PR, Curitiba, Brazil; email: claudia.dossantos@fiocruz.br. |
| المصدر: |
Annual review of virology [Annu Rev Virol] 2024 Jun 07. Date of Electronic Publication: 2024 Jun 07. |
| Publication Model: |
Ahead of Print |
| نوع المنشور: |
Journal Article; Review |
| اللغة: |
English |
| بيانات الدورية: |
Publisher: Annual Reviews Country of Publication: United States NLM ID: 101625721 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2327-0578 (Electronic) Linking ISSN: 2327056X NLM ISO Abbreviation: Annu Rev Virol Subsets: MEDLINE |
| أسماء مطبوعة: |
Original Publication: Palo Alto, California : Annual Reviews, 2014- |
| مستخلص: |
South American ecosystems host astonishing biodiversity, with potentially great richness in viruses. However, these ecosystems have not yet been the source of any widespread, epidemic viruses. Here we explore a set of putative causes that may explain this apparent paradox. We discuss that human presence in South America is recent, beginning around 14,000 years ago; that few domestications of native species have occurred; and that successive immigration events associated with Old World virus introductions reduced the likelihood of spillovers and adaptation of local viruses into humans. Also, the diversity and ecological characteristics of vertebrate hosts might serve as protective factors. Moreover, although forest areas remained well preserved until recently, current brutal, sudden, and large-scale clear cuts through the forest have resulted in nearly no ecotones, which are essential for creating an adaptive gradient of microbes, hosts, and vectors. This may be temporarily preventing virus emergence. Nevertheless, the mid-term effect of such drastic changes in habitats and landscapes, coupled with explosive urbanization and climate changes, must not be overlooked by health authorities. |
| تواريخ الأحداث: |
Date Created: 20240607 Latest Revision: 20240607 |
| رمز التحديث: |
20240608 |
| DOI: |
10.1146/annurev-virology-100422-024648 |
| PMID: |
38848594 |
| قاعدة البيانات: |
MEDLINE |
