دورية أكاديمية
Synthesis of homologous series of surfactants from renewable resources, structure-properties relationship, surface active performance, evaluation of their antimicrobial and anticancer potentialities.
| العنوان: | Synthesis of homologous series of surfactants from renewable resources, structure-properties relationship, surface active performance, evaluation of their antimicrobial and anticancer potentialities. |
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| المؤلفون: | Abdelaziz SA; Chemistry Department, Faculty of Science, Al-Azhar University (Girls), Cairo, Egypt. Shimaaabdelaziz.59@azhar.edu.eg., Ahmed EM; Chemistry Department, Faculty of Science, Al-Azhar University (Girls), Cairo, Egypt., Sadek M; Chemistry Department, Faculty of Science, Al-Azhar University (Girls), Cairo, Egypt. Mohamed.taher0940@gmail.com. |
| المصدر: | Scientific reports [Sci Rep] 2024 Jun 08; Vol. 14 (1), pp. 13201. Date of Electronic Publication: 2024 Jun 08. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: London : Nature Publishing Group, copyright 2011- |
| مواضيع طبية MeSH: | Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemical synthesis , Antineoplastic Agents*/chemistry , Surface-Active Agents*/chemistry , Surface-Active Agents*/chemical synthesis , Surface-Active Agents*/pharmacology , Anti-Infective Agents*/pharmacology , Anti-Infective Agents*/chemistry , Anti-Infective Agents*/chemical synthesis, Humans ; Structure-Activity Relationship ; Microbial Sensitivity Tests ; Esters/chemistry ; Esters/pharmacology ; Esters/chemical synthesis ; Cell Line, Tumor ; Amino Acids/chemistry |
| مستخلص: | Sugar esters display surface-active properties, wetting, emulsifying, and other physicochemical phenomena following their amphipathic nature and recognize distinct biological activity. The development of nutritional pharmaceuticals and other applications remains of great interest. Herein, three novel homologous series of several N-mono-fatty acyl amino acid glucosyl esters were synthesized, and their physicochemical properties and biological activities were evaluated. The design and preparation of these esters were chemically performed via the reaction of glucose with different fatty acyl amino acids as renewable starting materials, with the suggestion that they would acquire functional characteristics superior and competitive to certain conventional surfactants. The synthesized products are characterized using FTIR, 1 H-NMR, and 13 C-NMR spectroscopy. Further, their physicochemical properties, such as HLB, CMC, Γ (© 2024. The Author(s).) |
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| فهرسة مساهمة: | Keywords: Antitumor activity; Cysteine; Glucosyl ester; Hydrophile-lipophile balance (HLB); Surface active performance; Surfactant |
| المشرفين على المادة: | 0 (Antineoplastic Agents) 0 (Surface-Active Agents) 0 (Anti-Infective Agents) 0 (Esters) 0 (Amino Acids) |
| تواريخ الأحداث: | Date Created: 20240608 Date Completed: 20240608 Latest Revision: 20240627 |
| رمز التحديث: | 20240627 |
| مُعرف محوري في PubMed: | PMC11162424 |
| DOI: | 10.1038/s41598-024-62905-3 |
| PMID: | 38851845 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 2045-2322 |
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| DOI: | 10.1038/s41598-024-62905-3 |