التفاصيل البيبلوغرافية
| العنوان: |
The plasticity of pyramidal neurons in the behaving brain. |
| المؤلفون: |
Regele-Blasco E; The Florey Institute of Neuroscience and Mental Health, The Florey Department of Neuroscience and Mental Health, University of Melbourne , Victoria 3052, Australia., Palmer LM; The Florey Institute of Neuroscience and Mental Health, The Florey Department of Neuroscience and Mental Health, University of Melbourne , Victoria 3052, Australia. |
| المصدر: |
Philosophical transactions of the Royal Society of London. Series B, Biological sciences [Philos Trans R Soc Lond B Biol Sci] 2024 Jul 29; Vol. 379 (1906), pp. 20230231. Date of Electronic Publication: 2024 Jun 10. |
| نوع المنشور: |
Journal Article; Review |
| اللغة: |
English |
| بيانات الدورية: |
Publisher: Royal Society Country of Publication: England NLM ID: 7503623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-2970 (Electronic) Linking ISSN: 09628436 NLM ISO Abbreviation: Philos Trans R Soc Lond B Biol Sci Subsets: MEDLINE |
| أسماء مطبوعة: |
Original Publication: London : Royal Society, 1934- |
| مواضيع طبية MeSH: |
Pyramidal Cells*/physiology , Neuronal Plasticity*/physiology, Animals ; Brain/physiology ; Brain/cytology ; Long-Term Potentiation/physiology ; Synapses/physiology ; Humans |
| مستخلص: |
Neurons are plastic. That is, they change their activity according to different behavioural conditions. This endows pyramidal neurons with an incredible computational power for the integration and processing of synaptic inputs. Plasticity can be investigated at different levels of investigation within a single neuron, from spines to dendrites, to synaptic input. Although most of our knowledge stems from the in vitro brain slice preparation, plasticity plays a vital role during behaviour by providing a flexible substrate for the execution of appropriate actions in our ever-changing environment. Owing to advances in recording techniques, the plasticity of neurons and the neural networks in which they are embedded is now beginning to be realized in the in vivo intact brain. This review focuses on the structural and functional synaptic plasticity of pyramidal neurons , with a specific focus on the latest developments from in vivo studies. This article is part of a discussion meeting issue 'Long-term potentiation: 50 years on'. |
| معلومات مُعتمدة: |
Sylvia and Charles Viertel Charitable Foundation |
| فهرسة مساهمة: |
Keywords: dendrites; in vivo; plasticity; pyramidal neurons; spines |
| تواريخ الأحداث: |
Date Created: 20240610 Date Completed: 20240610 Latest Revision: 20240612 |
| رمز التحديث: |
20240613 |
| DOI: |
10.1098/rstb.2023.0231 |
| PMID: |
38853566 |
| قاعدة البيانات: |
MEDLINE |
