التفاصيل البيبلوغرافية
| العنوان: |
Parathyroid Gland Generation from Pluripotent Stem Cells. |
| المؤلفون: |
Kano M; Department of Metabolism and Endocrinology, St. Marianna University School of Medicine, Kawasaki, Japan. |
| المصدر: |
Endocrinology and metabolism (Seoul, Korea) [Endocrinol Metab (Seoul)] 2024 Aug; Vol. 39 (4), pp. 552-558. Date of Electronic Publication: 2024 Jun 10. |
| نوع المنشور: |
Journal Article; Review |
| اللغة: |
English |
| بيانات الدورية: |
Publisher: Korean Endocrine Society Country of Publication: Korea (South) NLM ID: 101554139 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2093-5978 (Electronic) Linking ISSN: 2093596X NLM ISO Abbreviation: Endocrinol Metab (Seoul) Subsets: MEDLINE |
| أسماء مطبوعة: |
Original Publication: Seoul : Korean Endocrine Society, [2010]- |
| مواضيع طبية MeSH: |
Parathyroid Glands* , Cell Differentiation* , Induced Pluripotent Stem Cells*/cytology, Humans ; Animals ; Regenerative Medicine/methods ; Hypoparathyroidism ; Pluripotent Stem Cells/cytology |
| مستخلص: |
Patients with permanent hypoparathyroidism require lifelong treatment. Current replacement therapies sometimes have adverse effects (e.g., hypercalciuria and chronic kidney disease). Generating parathyroid glands (PTGs) from the patient's own induced pluripotent stem cells (PSCs), with transplantation of these PTGs, would be an effective treatment option. Multiple methods for generating PTGs from PSCs have been reported. One major trend is in vitro differentiation of PSCs into PTGs. Another is in vivo generation of PSC-derived PTGs by injecting PSCs into PTG-deficient embryos. This review discusses current achievements and challenges in present and future PTG regenerative medicine. |
| معلومات مُعتمدة: |
JP21K16337 Japan Society for the Promotion of Science; 24K19296 Japan Society for the Promotion of Science; Japan Medical Women's Association; Yamaguchi Endocrine Research Foundation; Uehara Memorial Foundation |
| فهرسة مساهمة: |
Keywords: Parathyroid glands; Pluripotent stem cells; Regenerative medicine |
| تواريخ الأحداث: |
Date Created: 20240610 Date Completed: 20240903 Latest Revision: 20240903 |
| رمز التحديث: |
20240903 |
| DOI: |
10.3803/EnM.2024.1989 |
| PMID: |
38853617 |
| قاعدة البيانات: |
MEDLINE |
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