دورية أكاديمية
أعرض في EDS

Successful treatment with reduced oral steroid dosage in an 81-year-old woman with statin-induced anti-HMGCR immune-mediated necrotizing myopathy.

التفاصيل البيبلوغرافية
العنوان: Successful treatment with reduced oral steroid dosage in an 81-year-old woman with statin-induced anti-HMGCR immune-mediated necrotizing myopathy.
المؤلفون: Kondo S; Department of Neurology, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, Japan., Kurihara M; Department of Neurology, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, Japan., Higashihara M; Department of Neurology, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, Japan., Hara M; Department of Neuropathology (Brain Bank for Aging Research), Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, Japan., Nishina Y; Department of Neurology, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, Japan., Iwakiri R; Department of Geriatrics, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, Japan., Murayama S; Department of Neuropathology (Brain Bank for Aging Research), Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, Japan., Saito Y; Department of Neuropathology (Brain Bank for Aging Research), Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, Japan., Iwata A; Department of Neurology, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, Japan.
المصدر: Geriatrics & gerontology international [Geriatr Gerontol Int] 2024 Jul; Vol. 24 (7), pp. 739-742. Date of Electronic Publication: 2024 Jun 11.
نوع المنشور: Case Reports; Journal Article; Letter
اللغة: English
بيانات الدورية: Publisher: Japan Geriatrics Society Country of Publication: Japan NLM ID: 101135738 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1447-0594 (Electronic) Linking ISSN: 14470594 NLM ISO Abbreviation: Geriatr Gerontol Int Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [Tokyo, Japan] : Carlton, Vic., Australia : Japan Geriatrics Society ; Blackwell Science, c2001-
مواضيع طبية MeSH: Hydroxymethylglutaryl-CoA Reductase Inhibitors*/adverse effects , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/administration & dosage , Muscular Diseases*/drug therapy , Muscular Diseases*/chemically induced , Muscular Diseases*/immunology , Muscular Diseases*/diagnosis, Humans ; Female ; Aged, 80 and over ; Necrosis ; Glucocorticoids/administration & dosage ; Glucocorticoids/therapeutic use ; Administration, Oral ; Hydroxymethylglutaryl CoA Reductases/immunology
مستخلص: An 81-year-old woman presented with statin-induced anti-HMGCR immune-mediated necrotizing myopathy. Treatment was successful without complications with a reduced oral steroid dosage from the current consensus for all ages and backgrounds. This case suggests the importance of early diagnosis and the possibility of steroid dosage adjustment considering the patient's age, disease severity, and comorbidities.
(© 2024 Japan Geriatrics Society.)
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معلومات مُعتمدة: JP20FC1049 Ministry of Health, Labor, and Welfare; JP22wm0425019 Japan Agency for Medical Research and Development; JP22H04923 Japan Society for the Promotion of Science; JP23K14789 Japan Society for the Promotion of Science
فهرسة مساهمة: Keywords: HMG‐CoA reductase; aged 80 and over; multimorbidity; myopathies; statin
المشرفين على المادة: 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors)
0 (Glucocorticoids)
EC 1.1.1.- (Hydroxymethylglutaryl CoA Reductases)
EC 1.1.1.- (HMGCR protein, human)
تواريخ الأحداث: Date Created: 20240611 Date Completed: 20240701 Latest Revision: 20240722
رمز التحديث: 20240722
DOI: 10.1111/ggi.14922
PMID: 38860537
قاعدة البيانات: MEDLINE
الوصف
تدمد:1447-0594
DOI:10.1111/ggi.14922