Human cystic echinococcosis: first molecular identification of Echinococcus canadensis G7 in Brazil.

التفاصيل البيبلوغرافية
العنوان:	Human cystic echinococcosis: first molecular identification of Echinococcus canadensis G7 in Brazil.
المؤلفون:	das Neves LB; Laboratório de Parasitologia Integrativa e Paleoparasitologia (LPIP), Instituto Oswaldo Cruz (IOC), Fiocruz, Av. Brasil 4.365, Manguinhos, Rio de Janeiro, 21041-250, Brazil., Dias-Correia TP; Laboratório de Parasitologia Integrativa e Paleoparasitologia (LPIP), Instituto Oswaldo Cruz (IOC), Fiocruz, Av. Brasil 4.365, Manguinhos, Rio de Janeiro, 21041-250, Brazil., Bittencourt-Oliveira F; Laboratório de Parasitologia Integrativa e Paleoparasitologia (LPIP), Instituto Oswaldo Cruz (IOC), Fiocruz, Av. Brasil 4.365, Manguinhos, Rio de Janeiro, 21041-250, Brazil., Pereira TC; Laboratório de Parasitologia Integrativa e Paleoparasitologia (LPIP), Instituto Oswaldo Cruz (IOC), Fiocruz, Av. Brasil 4.365, Manguinhos, Rio de Janeiro, 21041-250, Brazil., de Almeida FB; Laboratório de Parasitologia Integrativa e Paleoparasitologia (LPIP), Instituto Oswaldo Cruz (IOC), Fiocruz, Av. Brasil 4.365, Manguinhos, Rio de Janeiro, 21041-250, Brazil., Rodrigues-Silva R; Laboratório de Parasitologia Integrativa e Paleoparasitologia (LPIP), Instituto Oswaldo Cruz (IOC), Fiocruz, Av. Brasil 4.365, Manguinhos, Rio de Janeiro, 21041-250, Brazil. rsilva@ioc.fiocruz.br.
المصدر:	Parasitology research [Parasitol Res] 2024 Jun 11; Vol. 123 (6), pp. 239. Date of Electronic Publication: 2024 Jun 11.
نوع المنشور:	Journal Article; Case Reports
اللغة:	English
بيانات الدورية:	Publisher: Springer International Country of Publication: Germany NLM ID: 8703571 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1955 (Electronic) Linking ISSN: 09320113 NLM ISO Abbreviation: Parasitol Res Subsets: MEDLINE
أسماء مطبوعة:	Original Publication: Berlin : Springer International, c1987-
مواضيع طبية MeSH:	Echinococcus/genetics , Echinococcus/classification , Echinococcus/isolation & purification , Phylogeny , DNA, Helminth*/genetics, Animals ; Brazil/epidemiology ; Humans ; Echinococcosis/veterinary ; Echinococcosis/parasitology ; Echinococcosis/epidemiology ; Sequence Analysis, DNA ; Polymerase Chain Reaction ; DNA, Mitochondrial/genetics ; Male
مستخلص:	Echinococcus granulosus sensu lato (s.l.) is a species complex with the potential to cause cystic echinococcosis (CE). Contact with the feces of domestic dogs (Canis familiaris) fed with raw viscera of intermediate livestock hosts is a risk factor for this infection in the southern region of Brazil. Although the region has been considered endemic to CE for many years, molecular data regarding the species of the complex causing CE in humans are scarce. This study aimed to perform a molecular analysis of the biological fluid from a human liver cyst to investigate the species responsible for CE. Genetic material obtained from the hydatid fluid of a hepatic cyst from a human with CE was subjected to PCR to amplify mitochondrial and nuclear DNA sequences. The phylogenetic analysis confirmed the human infection by Echinococcus canadensis G7 in the state of Paraná, Brazil. This is the first molecular record of E. canadensis G7 infecting a human in Brazil, and it is important to reiterate the risk of human CE caused by this species in South America, as reported by a previous study in Patagonia, Argentina. From the epidemiological point of view, this finding is of great relevance for the southern region of Brazil, since this parasite has previously only been detected in pigs in the state of Rio Grande do Sul, neighboring Paraná. The finding points to the importance of this identification in the molecular epidemiology of E. granulosus s.l., especially in South America. (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
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فهرسة مساهمة:	Keywords: Echinococcus canadensis G7; Echinococcus granulosus senso latu; Brazil; Echinococcoses; PCR
المشرفين على المادة:	0 (DNA, Helminth) 0 (DNA, Mitochondrial)
تواريخ الأحداث:	Date Created: 20240611 Date Completed: 20240611 Latest Revision: 20240703
رمز التحديث:	20240703
DOI:	10.1007/s00436-024-08262-6
PMID:	38860991
قاعدة البيانات:	MEDLINE

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تدمد:	1432-1955
DOI:	10.1007/s00436-024-08262-6