دورية أكاديمية

Knowledge, Adherence, and Satisfaction With Warfarin Therapy and Associated Factors Among Outpatients at University Teaching Hospital in Ethiopia.

التفاصيل البيبلوغرافية
العنوان: Knowledge, Adherence, and Satisfaction With Warfarin Therapy and Associated Factors Among Outpatients at University Teaching Hospital in Ethiopia.
المؤلفون: Tadesse TA; Department of Pharmaceutics and Social Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.; Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia., Yadeta D; Department of Internal Medicine, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia., Chelkeba L; Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia., Gebremedhin A; Department of Internal Medicine, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia., Fenta TG; Department of Pharmaceutics and Social Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
المصدر: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis [Clin Appl Thromb Hemost] 2024 Jan-Dec; Vol. 30, pp. 10760296241260736.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Sage Publications Country of Publication: United States NLM ID: 9508125 Publication Model: Print Cited Medium: Internet ISSN: 1938-2723 (Electronic) Linking ISSN: 10760296 NLM ISO Abbreviation: Clin Appl Thromb Hemost Subsets: MEDLINE
أسماء مطبوعة: Publication: Thousand Oaks, CA : Sage Publications
Original Publication: New York, N.Y. : Raven Press, c1995-
مواضيع طبية MeSH: Warfarin*/therapeutic use , Patient Satisfaction* , Outpatients*, Humans ; Ethiopia ; Female ; Male ; Middle Aged ; Cross-Sectional Studies ; Adult ; Anticoagulants/therapeutic use ; Medication Adherence/statistics & numerical data ; Health Knowledge, Attitudes, Practice ; Aged ; Hospitals, Teaching ; Hospitals, University ; Surveys and Questionnaires
مستخلص: Anticoagulation management using warfarin is challenging in clinical practice. This study aimed to evaluate the knowledge, adherence, and satisfaction with warfarin therapy and associated factors among outpatients at the Tikur Anbessa Specialized Hospital (TASH) in Addis Ababa, Ethiopia. An interview-based cross-sectional study was conducted among 350 patients receiving warfarin therapy at cardiac and hematology clinics of TASH. Anticoagulation knowledge assessment (AKA) questionnaires assessed the patients' warfarin knowledge. Adherence to warfarin was evaluated using the Morisky Green Levine Scale (MGLS), and patient satisfaction with warfarin therapy was assessed using the 17-item anticlot treatment scale (ACTS). Binary logistic regression was used to determine factors associated with the outcome variables, and p  < .05 was used as the cut-off point to declare a significant association. The mean AKA score was 59.35  ±  13.04% (10.68  ±  2.34 correct answers), and 82 (23.4%) of participants achieved a passing score. Based on the MGLS, 192 (54.9%) study participants adhered well to warfarin. The mean level of satisfaction was 53.67  ±  8.56, with mean scores of 41.93  ±  7.80 and 11.74  ±  2.43 in the ACTS burden and benefit subscales, respectively. One hundred eighty-four (52.6%) patients were satisfied with warfarin therapy. The absence of hyperthyroidism was significantly associated with poor knowledge of warfarin therapy (adjusted odds ratio [AOR] = 4.28, 95% confidence interval [CI]: 1.01-18.22). Those living with family had a 56% lower chance of poor warfarin adherence (AOR: 0.44; 95% CI: 0.21-0.93) than those living alone. This study shows room for improvement in patient knowledge, adherence, and satisfaction with warfarin therapy.
Competing Interests: Declaration of Conflicting InterestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
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فهرسة مساهمة: Keywords: adherence; anticlot treatment scale; anticoagulation knowledge assessment; warfarin
المشرفين على المادة: 5Q7ZVV76EI (Warfarin)
0 (Anticoagulants)
تواريخ الأحداث: Date Created: 20240612 Date Completed: 20240612 Latest Revision: 20240618
رمز التحديث: 20240618
مُعرف محوري في PubMed: PMC11179514
DOI: 10.1177/10760296241260736
PMID: 38863211
قاعدة البيانات: MEDLINE
الوصف
تدمد:1938-2723
DOI:10.1177/10760296241260736