دورية أكاديمية
Complication of Intrapulmonary Cavitary Lesions after COVID-19 Finally Proved as Pulmonary Aspergillosis.
| العنوان: | Complication of Intrapulmonary Cavitary Lesions after COVID-19 Finally Proved as Pulmonary Aspergillosis. |
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| المؤلفون: | Zhang JB, Fu AS, Liu TJ, Ge YL, Jiang J, Li XR, Nie CX |
| المصدر: | Clinical laboratory [Clin Lab] 2024 Jun 01; Vol. 70 (6). |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Clinical Laboratory Publications Country of Publication: Germany NLM ID: 9705611 Publication Model: Print Cited Medium: Internet ISSN: 1433-6510 (Print) Linking ISSN: 14336510 NLM ISO Abbreviation: Clin Lab Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2010- : Mainz : Clinical Laboratory Publications Original Publication: Heidelberg : Verlag Klinisches Labor, [1997- |
| مواضيع طبية MeSH: | COVID-19*/complications , COVID-19*/diagnosis , Pulmonary Aspergillosis*/diagnosis , Pulmonary Aspergillosis*/complications , Tomography, X-Ray Computed*, Humans ; Male ; SARS-CoV-2/isolation & purification ; Lung/diagnostic imaging ; Lung/microbiology ; Middle Aged ; High-Throughput Nucleotide Sequencing ; Metagenomics/methods ; Female |
| مستخلص: | Background: Coronavirus Disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus type 2, which is characterized by high infectiousness and diverse clinical manifestations. They are more likely to become critical in people who have underlying diseases or are immunocompromised. In the daunting task of treating patients with COVID-19, those with comorbid fungal infections are susceptible to underdiagnosis or misdiagnosis, which can ultimately lead to increased morbidity and mortality in this group of patients. We report a case of intrapulmonary cavitary lesions after COVID-19, which was eventually diagnosed as pulmonary aspergillosis (PA) by metagenomic Next Generation Sequencing (mNGS) to improve our understanding of the disease. Methods: Appropriate laboratory tests, chest computed tomography (CT), mNGS, and serologic tests were performed for diagnosis. Results: Laboratory tests showed Glactomannan (GM) of 1.41, multiple cavitary lesions in both lungs on chest CT and the presence of aspergillus infection was confirmed by sputum sent for mNGS. Conclusions: In the case of cavitary lesions after COVID-19, we should be alert to the possibility of combined fungi and should promptly perform mNGS to clarify whether there is a combination of specific pathogenic fungal infections. |
| تواريخ الأحداث: | Date Created: 20240613 Date Completed: 20240613 Latest Revision: 20240613 |
| رمز التحديث: | 20240613 |
| DOI: | 10.7754/Clin.Lab.2024.240120 |
| PMID: | 38868879 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1433-6510 |
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| DOI: | 10.7754/Clin.Lab.2024.240120 |