دورية أكاديمية

Polytyrosine-Coated Paper Electrode for Sensitive and Selective Sensing of NADH.

التفاصيل البيبلوغرافية
العنوان: Polytyrosine-Coated Paper Electrode for Sensitive and Selective Sensing of NADH.
المؤلفون: Jain S; Polymer Nanobiomaterial Research Laboratory, Smart Materials and Devices, Yenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore 575 018, India., Sonia J; Nanomaterial Research Laboratory (NMRL), Smart Materials and Devices, Yenepoya Research Centre, Yenepoya (Deemed to be University), Deralakatte, Mangalore 575 018, India., Prashanth S; Nanomaterial Research Laboratory (NMRL), Smart Materials and Devices, Yenepoya Research Centre, Yenepoya (Deemed to be University), Deralakatte, Mangalore 575 018, India., Sanjeeva SG; Polymer Nanobiomaterial Research Laboratory, Smart Materials and Devices, Yenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore 575 018, India., Prasad KS; Nanomaterial Research Laboratory (NMRL), Smart Materials and Devices, Yenepoya Research Centre, Yenepoya (Deemed to be University), Deralakatte, Mangalore 575 018, India.; Centre for Nutrition Studies, Yenepoya (Deemed to be University), Deralakatte, Mangalore 575 018, India., Johnson RP; Polymer Nanobiomaterial Research Laboratory, Smart Materials and Devices, Yenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore 575 018, India.
المصدر: Langmuir : the ACS journal of surfaces and colloids [Langmuir] 2024 Jun 25; Vol. 40 (25), pp. 13144-13154. Date of Electronic Publication: 2024 Jun 13.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9882736 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5827 (Electronic) Linking ISSN: 07437463 NLM ISO Abbreviation: Langmuir Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Washington, DC : American Chemical Society, c1985-
مواضيع طبية MeSH: NAD*/analysis , NAD*/chemistry , Electrodes* , Paper*, Peptides/chemistry ; Electrochemical Techniques/methods ; Electrochemical Techniques/instrumentation ; Oxidation-Reduction ; Limit of Detection ; Biosensing Techniques/methods
مستخلص: Reduced nicotinamide adenine dinucleotide (NADH)-detecting electrochemical sensors are attractive in monitoring and diagnosing various physiological disorders of NADH abnormalities. The NADH detection methods using conventional electrodes are challenging due to slow electron transfer and fouling effect. Interestingly, paper-based flexible and disposable electrodes (PE) are superior for sensing biomolecules through simple detection procedures with excellent sensitivity and selectivity. Herein, to construct a conducting polypeptide-modified paper electrode, initially, polytyrosine (PTyr) is synthesized from l-tyrosine N-carboxy anhydride through ring-opening polymerization, and PTyr is drop-coated on the PE. The PTyr-modified paper electrode (PMPE) demonstrated excellent electrochemical properties and facilitated the electrooxidation of NADH at a lower potential of 576 mV. The PMPE displayed a linear detection between 25 and 145 μM of NADH concentration, with a lower detection limit of 0.340 μM. Under ideal circumstances, the sensor developed displayed an excellent NADH detection capability without interference with the most common electroactive species, ascorbic acid. The PMPE facilitates good electrocatalytic activity toward NADH, which can also be employed as a substrate material for biofuel cells.
المشرفين على المادة: 0U46U6E8UK (NAD)
31724-37-5 (polytyrosine)
0 (Peptides)
تواريخ الأحداث: Date Created: 20240613 Date Completed: 20240625 Latest Revision: 20240625
رمز التحديث: 20240625
DOI: 10.1021/acs.langmuir.4c01125
PMID: 38869442
قاعدة البيانات: MEDLINE
الوصف
تدمد:1520-5827
DOI:10.1021/acs.langmuir.4c01125