دورية أكاديمية
أعرض في EDS

Dietary supplementations to mitigate the cardiopulmonary effects of air pollution toxicity: A systematic review of clinical trials.

التفاصيل البيبلوغرافية
العنوان: Dietary supplementations to mitigate the cardiopulmonary effects of air pollution toxicity: A systematic review of clinical trials.
المؤلفون: Ilaghi M; Institute of Neuropharmacology, Kerman Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, Iran., Kafi F; School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran., Shafiei M; Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran., Zangiabadian M; Endocrinology and Metabolism Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran., Nasiri MJ; Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
المصدر: PloS one [PLoS One] 2024 Jun 13; Vol. 19 (6), pp. e0304402. Date of Electronic Publication: 2024 Jun 13 (Print Publication: 2024).
نوع المنشور: Journal Article; Systematic Review
اللغة: English
بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
أسماء مطبوعة: Original Publication: San Francisco, CA : Public Library of Science
مواضيع طبية MeSH: Dietary Supplements* , Air Pollution*/adverse effects, Humans ; Antioxidants/administration & dosage ; Cardiovascular Diseases/prevention & control ; Clinical Trials as Topic ; Fish Oils/administration & dosage ; Ascorbic Acid/administration & dosage
مستخلص: Background: There is a consistent association between exposure to air pollution and elevated rates of cardiopulmonary illnesses. As public health activities emphasize the paramount need to reduce exposure, it is crucial to examine strategies like the antioxidant diet that could potentially protect individuals who are unavoidably exposed.
Methods: A systematic search was performed in PubMed/Medline, EMBASE, CENTRAL, and ClinicalTrials.gov up to March 31, 2023, for clinical trials assessing dietary supplements against cardiovascular (blood pressure, heart rate, heart rate variability, brachial artery diameter, flow-mediated dilation, and lipid profile) or pulmonary outcomes (pulmonary function and airway inflammation) attributed to air pollution exposure.
Results: After reviewing 4681 records, 18 studies were included. There were contradictory findings on the effects of fish oil and olive oil supplementations on cardiovascular outcomes. Although with limited evidence, fish oil offered protection against pulmonary dysfunction induced by pollutants. Most studies on vitamin C did not find protective cardiovascular effects; however, the combination of vitamin C and E offered protective effects against pulmonary dysfunction but showed conflicting results for cardiovascular outcomes. Other supplements like sulforaphane, L-arginine, n-acetylcysteine, and B vitamins showed potential beneficial effects but need further research due to the limited number of existing trials.
Conclusions: Although more research is needed to determine the efficacy and optimal dose of anti-inflammatory and antioxidant dietary supplements against air pollution toxicity, this low-cost preventative strategy has the potential to offer protection against outcomes of air pollution exposure.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: © 2024 Ilaghi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
References: Am J Respir Crit Care Med. 2002 Sep 1;166(5):703-9. (PMID: 12204869)
Future Cardiol. 2012 Jul;8(4):577-602. (PMID: 22871197)
Toxicol Res. 2014 Jun;30(2):71-5. (PMID: 25071915)
Heart. 2012 Aug;98(15):1127-35. (PMID: 22628541)
Environ Health Perspect. 2015 Nov;123(11):1173-9. (PMID: 25933197)
Free Radic Res. 2005 Jul;39(7):671-86. (PMID: 16036346)
Toxicol Sci. 2014 Jun;139(2):479-87. (PMID: 24814479)
Respir Med. 1995 Nov;89(10):647-56. (PMID: 8570878)
Arch Environ Health. 2001 May-Jun;56(3):242-9. (PMID: 11480500)
Am J Respir Crit Care Med. 2001 Sep 1;164(5):819-25. (PMID: 11549539)
Free Radic Biol Med. 2011 Jul 15;51(2):516-21. (PMID: 21605660)
J Cancer Prev. 2021 Mar 30;26(1):64-70. (PMID: 33842407)
Int J Environ Res Public Health. 2020 Jan 18;17(2):. (PMID: 31963738)
Free Radic Biol Med. 2006 May 15;40(10):1702-12. (PMID: 16767844)
Environ Res. 2019 Mar;170:194-202. (PMID: 30590262)
Toxicol Sci. 2018 May 1;163(1):57-69. (PMID: 29329427)
J Toxicol Environ Health. 1986;18(3):491-7. (PMID: 3712504)
Respir Res. 2018 May 2;19(1):79. (PMID: 29716592)
Pharmacol Ther. 2022 Apr;232:107996. (PMID: 34571110)
Oxid Med Cell Longev. 2018 Apr 22;2018:2835787. (PMID: 29849877)
Nutrients. 2020 May 21;12(5):. (PMID: 32455696)
Am J Respir Crit Care Med. 2005 Dec 15;172(12):1534-40. (PMID: 16210665)
J Am Coll Cardiol. 2019 Apr 30;73(16):2076-2085. (PMID: 31023432)
Arterioscler Thromb Vasc Biol. 2002 Apr 1;22(4):699-703. (PMID: 11950713)
Environ Health Perspect. 2010 Apr;118(4):465-71. (PMID: 20064776)
J Am Coll Cardiol. 2011 Nov 8;58(20):2047-67. (PMID: 22051327)
Curr Alzheimer Res. 2011 Aug;8(5):452-69. (PMID: 21605052)
Res Synth Methods. 2021 Jan;12(1):55-61. (PMID: 32336025)
J Am Heart Assoc. 2015 Jan 27;4(1):e001423. (PMID: 25628407)
Diabetes Care. 2021 Feb;44(2):618-630. (PMID: 33472962)
Respir Res. 2016 Jul 22;17(1):89. (PMID: 27450419)
Antioxid Redox Signal. 2013 Dec 10;19(17):2068-83. (PMID: 23581713)
Respir Res. 2023 Jul 13;24(1):187. (PMID: 37443038)
Food Funct. 2014 Jan;5(1):35-41. (PMID: 24287881)
Respiration. 2005 Jan-Feb;72(1):79-84. (PMID: 15753639)
Allergy. 2002 Aug;57(8):737-40. (PMID: 12121195)
BMJ. 2019 Aug 28;366:l4898. (PMID: 31462531)
N Engl J Med. 2011 Jun 23;364(25):2439-50. (PMID: 21696310)
Adv Exp Med Biol. 2015;873:43-52. (PMID: 26285609)
Environ Int. 2021 Nov;156:106631. (PMID: 34004448)
Biochim Biophys Acta Gen Subj. 2017 Mar;1861(3):577-584. (PMID: 28011301)
Front Public Health. 2020 Dec 11;8:575137. (PMID: 33425832)
Adv Exp Med Biol. 1990;264:155-63. (PMID: 2244489)
Mutat Res. 2004 Sep;567(1):1-61. (PMID: 15341901)
Inflamm Res. 2011 Jul;60(7):695-704. (PMID: 21424515)
Am J Respir Crit Care Med. 2016 May 1;193(9):1000-7. (PMID: 26599707)
Toxics. 2023 Oct 31;11(11):. (PMID: 37999546)
Environ Res Lett. 2011 Apr;6(2):. (PMID: 21779304)
Hypertension. 2009 Sep;54(3):659-67. (PMID: 19620518)
Int J Environ Res Public Health. 2021 Sep 20;18(18):. (PMID: 34574829)
Am J Respir Crit Care Med. 2019 Oct 15;200(8):1022-1031. (PMID: 31051079)
Prostate. 2009 Feb 1;69(2):181-90. (PMID: 18973173)
Pharmacol Res. 2013 Dec;78:28-40. (PMID: 24121007)
Antioxid Redox Signal. 2018 Mar 20;28(9):797-818. (PMID: 29084451)
J Dermatol Sci. 2014 Dec;76(3):163-8. (PMID: 25278222)
Int J Surg. 2021 Apr;88:105906. (PMID: 33789826)
Environ Health Perspect. 2012 Jul;120(7):952-7. (PMID: 22514211)
Inhal Toxicol. 2020 Jun;32(7):279-281. (PMID: 32727225)
Circulation. 2001 Jun 12;103(23):2788-91. (PMID: 11401933)
Circulation. 2004 Jan 6;109(1):71-7. (PMID: 14676145)
Environ Int. 2022 Sep;167:107407. (PMID: 35850080)
Ecotoxicol Environ Saf. 2022 Aug;241:113735. (PMID: 35689890)
Antioxid Redox Signal. 2014 Sep 10;21(8):1156-63. (PMID: 24597798)
Chemosphere. 2016 Feb;144:459-66. (PMID: 26386771)
Sci Rep. 2020 Oct 6;10(1):16538. (PMID: 33024194)
Sci Rep. 2017 Apr 03;7:45322. (PMID: 28367952)
Antioxidants (Basel). 2021 Jun 16;10(6):. (PMID: 34208683)
المشرفين على المادة: 0 (Antioxidants)
0 (Fish Oils)
PQ6CK8PD0R (Ascorbic Acid)
تواريخ الأحداث: Date Created: 20240613 Date Completed: 20240613 Latest Revision: 20240620
رمز التحديث: 20240620
مُعرف محوري في PubMed: PMC11175466
DOI: 10.1371/journal.pone.0304402
PMID: 38870164
قاعدة البيانات: MEDLINE
الوصف
تدمد:1932-6203
DOI:10.1371/journal.pone.0304402