دورية أكاديمية
APPaRENT 3: Asthma Patients' and Physicians' Perspectives on the Burden and Management of Asthma in Seven Countries.
| العنوان: | APPaRENT 3: Asthma Patients' and Physicians' Perspectives on the Burden and Management of Asthma in Seven Countries. |
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| المؤلفون: | Aggarwal B; General Medicines, GSK, 23 Rochester Park, #06-01, GSK Asia House, Singapore, 139234, Singapore. bhumika.x.aggarwal@gsk.com., Al-Moamary M; Department of Medicine, College of Medicine, King Saudi Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia., Allehebi R; Department of Pulmonology, King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia.; College of Medicine, Alfaisal University, Riyadh, Kingdom of Saudi Arabia., Alzaabi A; Internal Medicine Department, College of Medicine and Health Sciences, UAE University, Abu Dhabi, United Arab Emirates.; Respirology Division, Zayed Military Hospital, Abu Dhabi, United Arab Emirates., Al-Ahmad M; Microbiology Department, College of Medicine, Kuwait University, Kuwait City, Kuwait., Amin M; Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Airlangga Hospital, Surabaya, Indonesia., Damayanti T; Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Indonesia, Persahabatan Hospital National Respiratory Center, Jakarta, Indonesia., Van Tho N; Department of Tuberculosis and Lung Diseases, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam., Quyen PTL; Respiratory Center, Bach Mai Hospital, Hanoi, Vietnam., Sriprasart T; Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand., Poachanukoon O; Center of Excellence for Allergy, Asthma and Pulmonary Diseases and Department of Pediatrics, Thammasat University, Pathum Thani, Thailand., Yu-Lin AB; Respiratory Unit, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia., Ismail AI; Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Selangor, Malaysia., Limpin MEB; Pulmonary and Critical Care Medicine Division, Philippine Heart Center, Quezon City, Philippines., Koenig S; St. Claire HealthCare, Morehead, KY, USA., Levy G; GSK, Panama City, Panama., Phansalkar A; GSK, Mumbai, India., Rafih F; GSK, Dubai, United Arab Emirates., Silvey M; Adelphi Real World, Bollington, UK., Miriams L; Adelphi Real World, Bollington, UK., Milligan G; Adelphi Real World, Bollington, UK. |
| المصدر: | Advances in therapy [Adv Ther] 2024 Aug; Vol. 41 (8), pp. 3089-3118. Date of Electronic Publication: 2024 Jun 14. |
| نوع المنشور: | Journal Article; Multicenter Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Health Communications Inc Country of Publication: United States NLM ID: 8611864 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1865-8652 (Electronic) Linking ISSN: 0741238X NLM ISO Abbreviation: Adv Ther Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: New York : Springer Healthcare Communications, 2008- : Health Communications Inc. Original Publication: Metuchen, N.J. : Health Communications Inc., c1984- |
| مواضيع طبية MeSH: | Asthma*/drug therapy , Asthma*/therapy , Anti-Asthmatic Agents*/therapeutic use , Anti-Asthmatic Agents*/administration & dosage, Humans ; Male ; Adult ; Female ; Cross-Sectional Studies ; Middle Aged ; Malaysia ; United Arab Emirates ; Vietnam ; Saudi Arabia ; Indonesia ; Attitude of Health Personnel ; Thailand ; Philippines ; Health Knowledge, Attitudes, Practice ; Surveys and Questionnaires ; Administration, Inhalation ; Nebulizers and Vaporizers ; Medication Adherence/statistics & numerical data ; Young Adult ; Cost of Illness ; Physicians/psychology |
| مستخلص: | Introduction: Asthma management is strongly dependent on physician and patient beliefs and perceptions about the disease and its long-term treatment. The APPaRENT 3 study was conducted to explore factors influencing treatment choice and to understand patients' and physicians' attitudes and perspectives on the use of controller inhalers in regular versus flexible dosing for asthma management. Methods: This cross-sectional survey of patients with asthma and treating physicians was conducted in seven countries: Indonesia, Malaysia, Philippines, Thailand, Vietnam (patient survey only), Saudi Arabia, and the United Arab Emirates. Assessment was carried out through an online/face-to-face questionnaire, where patients' viewpoints were focused on their attitudes and beliefs about asthma and treatment adherence, whereas physicians' viewpoints were gathered on their attitudes and beliefs about asthma management, knowledge of and adherence to asthma treatment guidelines, and asthma treatment regimens. Results: Overall, 1400 patients (mean age, 34 years) and 599 physicians (mean age, 43 years) were included in the survey. Physicians similarly prioritised symptom control (39%) and exacerbation reduction (40%) in moderate asthma, whereas patients prioritised symptom control (41%) over exacerbation reduction (22%). Although both groups (physicians, 86%; patients, 84%) perceived asthma as well-controlled, poor management was evident based on Asthma Control Test (ACT) scores (mean, 15.7; standard deviation, 4.14; 82% had an ACT score < 20) and high symptom burden (39% reported nighttime awakenings or early mornings ≥ 2 nights/week). Most patients (76%) with moderate asthma were prescribed regular dosing, with the most common treatment being inhaled corticosteroid (ICS)/long-acting β Conclusions: Despite high symptom burden, patients overestimated their level of asthma control. Physicians prioritised controlling symptoms and reducing exacerbations as treatment goals for moderate asthma, often prescribing regular dosing with ICS/LABA with as-needed inhaled SABA. (© 2024. The Author(s).) |
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| فهرسة مساهمة: | Keywords: Asthma; Asthma control; Asthma exacerbation; Asthma regimen; Guideline adherence; Patient viewpoints; Physician perspectives Local Abstract: [plain-language-summary] Managing asthma depends a lot on what doctors and patients think about the illness and its long-term treatment. This study looked into what influences treatment decisions and what patients and doctors think about using inhalers regularly or on an as-needed basis to manage asthma across seven countries (Indonesia, Malaysia, Philippines, Thailand, Vietnam [patient survey only], Saudi Arabia, and the United Arab Emirates). In this study, patients with asthma and doctors managing asthma completed an online/face-to-face questionnaire. The study aimed to understand what patients think about asthma and their treatment plan. Meanwhile, the doctors were asked what they think about managing asthma and how much they apply clinical guidelines for treating patients with asthma. Doctors believed it is equally important to control symptoms and prevent worsening of symptoms in patients with moderate asthma, while patients cared more about controlling symptoms than preventing worsening of symptoms. While doctors and patients both regarded asthma as well-controlled, many patients had low Asthma Control Test scores and experienced a lot of symptoms, suggesting that they are poor perceivers of asthma control. Most patients with moderate asthma were given regular treatment, usually with inhaled corticosteroid combined with long-acting β |
| المشرفين على المادة: | 0 (Anti-Asthmatic Agents) |
| تواريخ الأحداث: | Date Created: 20240614 Date Completed: 20240722 Latest Revision: 20240725 |
| رمز التحديث: | 20240726 |
| مُعرف محوري في PubMed: | PMC11263244 |
| DOI: | 10.1007/s12325-024-02900-2 |
| PMID: | 38874879 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1865-8652 |
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| DOI: | 10.1007/s12325-024-02900-2 |