دورية أكاديمية
أعرض في EDS

Effects of bisphenol A on reproduction, oxidative stress, and lipid regulation in the marine rotifer Brachionus plicatilis.

التفاصيل البيبلوغرافية
العنوان: Effects of bisphenol A on reproduction, oxidative stress, and lipid regulation in the marine rotifer Brachionus plicatilis.
المؤلفون: Yoon DS; Department of Biological Sciences, College of Science, Sungkyunkwan University, Suwon 16419, South Korea., Kim JS; Department of Food and Nutrition, College of Bio-Nano Technology, Gachon University, Seongnam 13120, South Korea., Hong MS; Department of Biological Sciences, College of Science, Sungkyunkwan University, Suwon 16419, South Korea; Department of Food and Nutrition, College of Bio-Nano Technology, Gachon University, Seongnam 13120, South Korea., Byeon E; Department of Biological Sciences, College of Science, Sungkyunkwan University, Suwon 16419, South Korea., Sayed AEH; Department of Zoology, Assiut University, Assiut 71516, Egypt., Park HG; Department of Marine Ecology and Environment, College of Life Sciences, Gangneung-Wonju National University, Gangneung 25457, South Korea., Lee JS; Department of Biological Sciences, College of Science, Sungkyunkwan University, Suwon 16419, South Korea. Electronic address: jslee2@skku.edu., Lee MC; Department of Food and Nutrition, College of Bio-Nano Technology, Gachon University, Seongnam 13120, South Korea. Electronic address: mclee314@gachon.ac.kr.
المصدر: Marine pollution bulletin [Mar Pollut Bull] 2024 Aug; Vol. 205, pp. 116553. Date of Electronic Publication: 2024 Jun 15.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 0260231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3363 (Electronic) Linking ISSN: 0025326X NLM ISO Abbreviation: Mar Pollut Bull Subsets: MEDLINE
أسماء مطبوعة: Publication: 2003- : Oxford : Elsevier
Original Publication: London, Macmillan.
مواضيع طبية MeSH: Benzhydryl Compounds*/toxicity , Oxidative Stress*/drug effects , Phenols*/toxicity , Reproduction*/drug effects , Lipid Metabolism*/drug effects , Rotifera*/drug effects , Rotifera*/physiology , Water Pollutants, Chemical*/toxicity, Animals ; Diacylglycerol O-Acyltransferase/genetics ; Diacylglycerol O-Acyltransferase/metabolism
مستخلص: This study reports the effects of bisphenol A (BPA) on the rotifer Brachionus plicatilis, focusing on growth performance, reproductive output, oxidative stress responses, and lipid metabolism genes. High BPA levels disrupted peak daily offspring production and led to oxidative stress and increased superoxide dismutase and catalase activity. The research identified distinctive monoacylglycerol O-acyltransferase (MGAT) and diacylglycerol O-acyltransferase (DGAT) genes in B. plicatilis, B. rotundiformis, and B. koreanus, enhancing understanding of lipid metabolism in these species. BPA exposure significantly altered MGAT and DGAT expression, and feeding status affected these regulatory patterns. When food was unavailable, BPA reduced DGAT2 and MGAT2a expression. However, under feeding conditions, DGAT2 and MGAT1 levels increased, indicating that nutritional status and BPA exposure interact to affect gene expression.
Competing Interests: Declaration of competing interest The authors declare no competing financial interest.
(Copyright © 2024 Elsevier Ltd. All rights reserved.)
فهرسة مساهمة: Keywords: Endocrine-disrupting chemical; Fecundity; Lipid metabolism; Oxidative stress
المشرفين على المادة: 0 (Benzhydryl Compounds)
MLT3645I99 (bisphenol A)
0 (Phenols)
0 (Water Pollutants, Chemical)
EC 2.3.1.20 (Diacylglycerol O-Acyltransferase)
تواريخ الأحداث: Date Created: 20240616 Date Completed: 20240723 Latest Revision: 20240723
رمز التحديث: 20240723
DOI: 10.1016/j.marpolbul.2024.116553
PMID: 38880034
قاعدة البيانات: MEDLINE
الوصف
تدمد:1879-3363
DOI:10.1016/j.marpolbul.2024.116553