Addition of Mask to High-flow Nasal Oxygen: A Strategy to Improve Oxygenation in Hypoxemic Respiratory Failure Secondary to COVID-19.

التفاصيل البيبلوغرافية
العنوان:	Addition of Mask to High-flow Nasal Oxygen: A Strategy to Improve Oxygenation in Hypoxemic Respiratory Failure Secondary to COVID-19.
المؤلفون:	Mantoo S; Assistant Professor, Department of Internal Medicine, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India., Khan UH; Associate Professor, Department of Geriatrics, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India., Bhat RQ; Senior Resident, Department of Internal Medicine, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India., Shah TH; Senior Resident, Department of Pulmonary Medicine, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India, Corresponding Author., Siraj F; Assistant Professor, Department of Internal Medicine, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India., Shabir A; Associate Professor, Department of Geriatrics, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India., Mehfooz N; Assistant Professor, Department of Pulmonary Medicine, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India., Qadri SM; Associate Professor, Department of Internal Medicine, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India., Bindroo M; Assistant Professor, Department of Rheumatology, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India., Koul AN; Additional Professor, Department of Internal Medicine, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India., Ahmad M; Additional Professor, Department of Rheumatology, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India., Sofi FA; Professor, Department of Rheumatology, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India., Shah S; Professor, Department of Pulmonary Medicine, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India., Jan RA; Professor, Department of Pulmonary Medicine, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India.
المصدر:	The Journal of the Association of Physicians of India [J Assoc Physicians India] 2024 Jun; Vol. 72 (6), pp. 49-53.
نوع المنشور:	Journal Article
اللغة:	English
بيانات الدورية:	Publisher: Association of Physicians of India Country of Publication: India NLM ID: 7505585 Publication Model: Print Cited Medium: Print ISSN: 0004-5772 (Print) Linking ISSN: 00045772 NLM ISO Abbreviation: J Assoc Physicians India Subsets: MEDLINE
أسماء مطبوعة:	Publication: Bombay : Association of Physicians of India Original Publication: Bombay [1953?]-
مواضيع طبية MeSH:	COVID-19/complications , COVID-19/therapy , Respiratory Insufficiency/therapy , Respiratory Insufficiency/etiology , Masks* , Oxygen Inhalation Therapy/methods , Oxygen Inhalation Therapy/instrumentation , Hypoxia/therapy , Hypoxia/etiology , Oxygen Saturation*, Humans ; Prospective Studies ; Male ; Female ; Middle Aged ; Oxygen/administration & dosage ; SARS-CoV-2 ; Adult ; Aged ; Cannula ; Respiratory Rate
مستخلص:	Purpose: High-flow nasal cannula (HFNO) reduces the need for invasive mechanical ventilation in COVID-19 patients with hypoxemic-respiratory failure. During HFNO entrainment of room air dilutes the delivered fractional inspiratory oxygen (FiO 2 ), thereby preventing improvement in oxygenation. The placement of a mask over HFNO to improve oxygenation has provided conflicting results. We aimed to determine and compare the effect of placing various mask types over HFNO on oxygen saturation (SPO 2 ). Materials and Methods: In this prospective physiological study 40 patients with COVID-19-associated hypoxemic respiratory failure on HFNO with O 2 concentration <92% were included. The effect of placing different masks over HFNO on oxygenation, respiratory rate, heart rate, blood pressure, patient comfort, and partial pressure of carbon dioxide level (pCO 2 ) was recorded after a prespecified time interval. Results: We observed a significantly higher mean SPO 2 and lower mean respiratory rate on using various study masks over HFNO compared to HFNO alone. On comparing various mask types, the use of N95 masks and nonrebreather (NRB) masks with O 2 showed a significant increase in O 2 concentration and reduction in respiratory rate compared to surgical mask (SM) and NRB without O 2 . The proportion of patients who achieved SPO 2 of >92% was higher with the use of N95 masks (47.5%) or NRB with O 2 (45%) over HFNO compared to SM (35%) and NRB without O 2 (35%). No significant change was observed in heart rate, blood pressure, and CO 2 level with the use of any mask over HFNO. Conclusion: This study demonstrates improvement in oxygenation and reduction in respiratory rate with the use of various masks over HFNO in patients of COVID-19-related hypoxemic-respiratory-failure. Significantly greater benefit was achieved with the use of N95 or NRB with O2 compared to SM or NRB without O2. (© Journal of the Association of Physicians of India 2024.)
المشرفين على المادة:	S88TT14065 (Oxygen)
تواريخ الأحداث:	Date Created: 20240617 Date Completed: 20240617 Latest Revision: 20240617
رمز التحديث:	20240617
DOI:	10.59556/japi.72.0411
PMID:	38881135
قاعدة البيانات:	MEDLINE

الوصف
تدمد:	0004-5772
DOI:	10.59556/japi.72.0411