دورية أكاديمية
أعرض في EDS

Chemical Compositions before and after Lactic Acid Fermentation of Isoflavone-Enriched Soybean Leaves and Their Anti-Obesity and Gut Microbiota Distribution Effects.

التفاصيل البيبلوغرافية
العنوان: Chemical Compositions before and after Lactic Acid Fermentation of Isoflavone-Enriched Soybean Leaves and Their Anti-Obesity and Gut Microbiota Distribution Effects.
المؤلفون: Lee HY; Department of Green Bio Science and Agri-Food Bio Convergence Institute, Gyeongsang National University, Jinju 52727, Republic of Korea., Cho DY; Department of Green Bio Science and Agri-Food Bio Convergence Institute, Gyeongsang National University, Jinju 52727, Republic of Korea., Jeong JB; Department of Green Bio Science and Agri-Food Bio Convergence Institute, Gyeongsang National University, Jinju 52727, Republic of Korea., Lee JH; Department of Green Bio Science and Agri-Food Bio Convergence Institute, Gyeongsang National University, Jinju 52727, Republic of Korea., Lee GY; Department of Green Bio Science and Agri-Food Bio Convergence Institute, Gyeongsang National University, Jinju 52727, Republic of Korea., Jang MY; Department of Green Bio Science and Agri-Food Bio Convergence Institute, Gyeongsang National University, Jinju 52727, Republic of Korea., Lee JH; Department of Life Resource Industry, Dong-A University, 37, Nakdong-Daero 550 Beon-gil, Saha-gu, Busan 49315, Republic of Korea., Cho KM; Department of Green Bio Science and Agri-Food Bio Convergence Institute, Gyeongsang National University, Jinju 52727, Republic of Korea.
المصدر: Nutrients [Nutrients] 2024 May 29; Vol. 16 (11). Date of Electronic Publication: 2024 May 29.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI Publishing
مواضيع طبية MeSH: Gastrointestinal Microbiome*/drug effects , Glycine max* , Plant Leaves* , Fermentation* , Isoflavones*/pharmacology , Obesity*/metabolism , Obesity*/microbiology , Diet, High-Fat*/adverse effects , Anti-Obesity Agents*/pharmacology , Lactic Acid*/metabolism, Animals ; Male ; Mice, Inbred C57BL ; Mice ; Dysbiosis
مستخلص: In this study, we prepared fermented products of isoflavone-enriched soybean leaves (IESLs) and analyzed their nutrients, isoflavones, anti-obesity efficacy, and effects on gut microbiota. Fermented IESLs (FIESLs) were found to be rich in nutrients, especially lauric acid, oleic acid, and linoleic acid. In addition, the concentrations of most essential free amino acids were increased compared to those of IESLs. The contents of bioactive compounds, such as total phenolic, total flavonoid, daidzein, and genistein, significantly increased as well. In addition, FIESLs administration in a high-fat diet (HFD) animal model improved the final body weight, epididymal fat, total lipid, triglyceride, total cholesterol, blood glucose, and leptin levels, as well as reverting microbiota dysbiosis. In conclusion, these findings indicate that FIESLs have the potential to inhibit obesity caused by HFDs and serve as a modulator of gut microbiota, offering the prevention of diet-induced gut dysbiosis and metabolite diseases associated with obesity.
References: Food Funct. 2015 Mar;6(3):834-41. (PMID: 25599885)
Food Chem. 2023 Jun 30;412:135552. (PMID: 36716627)
J Mol Med (Berl). 2017 Jan;95(1):1-8. (PMID: 27900395)
Antioxidants (Basel). 2023 Jan 28;12(2):. (PMID: 36829856)
Microorganisms. 2021 Mar 27;9(4):. (PMID: 33801755)
Food Funct. 2021 Oct 4;12(19):9151-9164. (PMID: 34606532)
J Agric Food Chem. 2016 Oct 5;64(39):7315-7324. (PMID: 27626287)
Bioresour Technol. 2022 Jan;344(Pt A):126166. (PMID: 34678452)
Microbiologyopen. 2017 Feb;6(1):. (PMID: 27804281)
Food Funct. 2017 Mar 22;8(3):1132-1143. (PMID: 28170016)
Food Res Int. 2022 Jul;157:111437. (PMID: 35761677)
Biotechnol Bioeng. 2005 Mar 20;89(6):670-9. (PMID: 15696537)
Molecules. 2018 Nov 21;23(11):. (PMID: 30469432)
Food Chem. 2021 Jun 30;348:129083. (PMID: 33517000)
J Sci Food Agric. 2023 Mar 30;103(5):2554-2563. (PMID: 36494898)
Food Res Int. 2014 Oct;64:527-536. (PMID: 30011684)
Food Sci Nutr. 2020 Feb 06;8(3):1562-1574. (PMID: 32180965)
Food Funct. 2014 Jul 25;5(7):1621-30. (PMID: 24873894)
Molecules. 2017 Apr 22;22(4):. (PMID: 28441731)
Int J Obes (Lond). 2008 Sep;32(9):1431-7. (PMID: 18607383)
Nutr Metab (Lond). 2016 Apr 30;13:31. (PMID: 27134637)
Food Chem. 2022 Mar 15;372:131335. (PMID: 34818743)
Food Chem. 2021 Mar 15;340:128199. (PMID: 33027719)
Food Sci Biotechnol. 2017 Feb 28;26(1):245-253. (PMID: 30263535)
J Med Food. 2015 Aug;18(8):899-908. (PMID: 25826408)
Nat Rev Endocrinol. 2019 May;15(5):288-298. (PMID: 30814686)
PeerJ. 2016 Oct 18;4:e2584. (PMID: 27781170)
Cell Metab. 2017 Jul 5;26(1):110-130. (PMID: 28625867)
Clin Chem. 1972 Jul;18(7):673-4. (PMID: 5037917)
Food Res Int. 2024 Feb;177:113875. (PMID: 38225139)
Arch Med Sci. 2011 Jun;7(3):501-7. (PMID: 22295035)
BMC Complement Med Ther. 2020 Sep 18;20(1):283. (PMID: 32948162)
Lipids. 2017 Jun;52(6):499-511. (PMID: 28429150)
معلومات مُعتمدة: RS-2023-00245096 National Research Foundation of Korea; 2016R1D1A1B01009898 National Research Foundation of Korea
فهرسة مساهمة: Keywords: anti-obesity; free amino acids; gut microbiota; isoflavone-enriched soybean leaves; isoflavones; lactic acid fermentation
المشرفين على المادة: 0 (Isoflavones)
0 (Anti-Obesity Agents)
33X04XA5AT (Lactic Acid)
تواريخ الأحداث: Date Created: 20240619 Date Completed: 20240619 Latest Revision: 20240620
رمز التحديث: 20240620
مُعرف محوري في PubMed: PMC11174423
DOI: 10.3390/nu16111693
PMID: 38892626
قاعدة البيانات: MEDLINE
الوصف
تدمد:2072-6643
DOI:10.3390/nu16111693