دورية أكاديمية
β-catenin nuclear translocation and WNT pathway mutations in ghost cell odontogenic carcinoma: A literature review and proposal of a new molecular-based classification "WNT pathway-altered malignant odontogenic tumor".
| العنوان: | β-catenin nuclear translocation and WNT pathway mutations in ghost cell odontogenic carcinoma: A literature review and proposal of a new molecular-based classification "WNT pathway-altered malignant odontogenic tumor". |
|---|---|
| المؤلفون: | Oh KY; Department of Oral Pathology, College of Dentistry, Dankook University, Cheonan, Republic of Korea. Electronic address: bigfish@snu.ac.kr. |
| المصدر: | Oral oncology [Oral Oncol] 2024 Aug; Vol. 155, pp. 106907. Date of Electronic Publication: 2024 Jun 19. |
| نوع المنشور: | Journal Article; Review; Letter |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: England NLM ID: 9709118 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0593 (Electronic) Linking ISSN: 13688375 NLM ISO Abbreviation: Oral Oncol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Amsterdam : Elsevier Original Publication: Oxford ; New York : Pergamon, c1997- |
| مواضيع طبية MeSH: | beta Catenin*/genetics , beta Catenin*/metabolism , Odontogenic Tumors*/genetics , Odontogenic Tumors*/pathology , Odontogenic Tumors*/metabolism , Wnt Signaling Pathway*/genetics , Mutation*, Humans ; Cell Nucleus/metabolism |
| مستخلص: | Ghost cell odontogenic carcinoma (GCOC) is defined as a rare type of odontogenic carcinoma that is characterized by ghost cells and occasional dentinoid. However, the current classification system based primarily on the presence of ghost cells has limitations in the diagnosis of GCOC and its histologic mimics including odontogenic carcinoma with dentinoid (OCD). This study reviewed previous studies on β-catenin nuclear translocation and WNT pathway mutations in GCOC and OCD and discussed the potential utility of a new molecular-based classification "WNT pathway-altered malignant odontogenic tumor" for these rare odontogenic tumors. Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2024 Elsevier Ltd. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Ghost cell odontogenic carcinoma; Molecular-based classification; Odontogenic carcinoma with dentinoid; WNT pathway; β-catenin |
| المشرفين على المادة: | 0 (beta Catenin) |
| تواريخ الأحداث: | Date Created: 20240620 Date Completed: 20240627 Latest Revision: 20240719 |
| رمز التحديث: | 20240719 |
| DOI: | 10.1016/j.oraloncology.2024.106907 |
| PMID: | 38901368 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1879-0593 |
|---|---|
| DOI: | 10.1016/j.oraloncology.2024.106907 |