دورية أكاديمية

Evaluation of setting kinetics, mechanical strength, ion release, and cytotoxicity of high-strength glass ionomer cement contained elastomeric micelles.

التفاصيل البيبلوغرافية
العنوان: Evaluation of setting kinetics, mechanical strength, ion release, and cytotoxicity of high-strength glass ionomer cement contained elastomeric micelles.
المؤلفون: Leenutaphong N; Faculty of Dentistry, Thammasat University, Pathum Thani, 12120, Thailand., Phantumvanit P; Faculty of Dentistry, Thammasat University, Pathum Thani, 12120, Thailand., Young AM; Division of Biomaterials and Tissue Engineering, UCL Eastman Dental Institute, Royal Free Hospital, Rowland Hill Street, London, NW3 2PF, UK., Panpisut P; Faculty of Dentistry, Thammasat University, Pathum Thani, 12120, Thailand. panpisut@tu.ac.th.; Thammasat University Research Unit in Dental and Bone Substitute Biomaterials, Thammasat University, Pathum Thani, 12120, Thailand. panpisut@tu.ac.th.
المصدر: BMC oral health [BMC Oral Health] 2024 Jun 20; Vol. 24 (1), pp. 713. Date of Electronic Publication: 2024 Jun 20.
نوع المنشور: Journal Article; Comparative Study
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101088684 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-6831 (Electronic) Linking ISSN: 14726831 NLM ISO Abbreviation: BMC Oral Health Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, [2001-
مواضيع طبية MeSH: Glass Ionomer Cements*/toxicity , Glass Ionomer Cements*/chemistry , Materials Testing* , Micelles* , Fibroblasts*/drug effects , Hardness* , Elastomers*/chemistry , Elastomers*/toxicity , Flexural Strength*, Animals ; Mice ; Aluminum/chemistry ; Fluorides/chemistry ; Strontium/chemistry ; Polycarboxylate Cement/chemistry ; Polycarboxylate Cement/toxicity ; Cell Survival/drug effects ; Microscopy, Electron, Scanning ; Surface Properties ; Pliability ; Kinetics ; Spectroscopy, Fourier Transform Infrared ; Stress, Mechanical ; Time Factors ; Biocompatible Materials/chemistry
مستخلص: Background: Low mechanical properties are the main limitation of glass ionomer cements (GICs). The incorporation of elastomeric micelles is expected to enhance the strength of GICs without detrimentally affecting their physical properties and biocompatibility. This study compared the chemical and mechanical properties, as well as the cytotoxicity, of elastomeric micelles-containing glass ionomer cement (DeltaFil, DT) with commonly used materials, including EQUIA Forte Fil (EF), Fuji IX GP Extra (F9), and Ketac Molar (KT).
Method: Powder particles of GICs were examined with SEM-EDX. Setting kinetics were assessed using ATR-FTIR. Biaxial flexural strength/modulus and Vickers surface microhardness were measured after immersion in water for 24 h and 4 weeks. The release of F, Al, Sr, and P in water over 8 weeks was analyzed using a fluoride-specific electrode and ICP-OES. The toxicity of the material extract on mouse fibroblasts was also evaluated.
Results: High fluoride levels in the powder were detected with EF and F9. DT demonstrated an initial delay followed by a faster acid reaction compared to other cements, suggesting an improved snap set. DT also exhibited superior flexural strength than other materials at both 24 h and 4 weeks but lower surface microhardness (p < 0.05). EF and F9 showed higher release of F, Al, and P than DT and KT. There was no statistically significant difference in fibroblast viability among the tested materials (p > 0.05).
Conclusions: Elastomeric micelles-containing glass ionomer cement (DT) exhibited satisfactory mechanical properties and cytocompatibility compared with other materials. DT could, therefore, potentially be considered an alternative high-strength GIC for load-bearing restorations.
(© 2024. The Author(s).)
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فهرسة مساهمة: Keywords: Elastomeric micelles; Glass Ionomer cements; Ion release; Mechanical properties; Setting kinetic
المشرفين على المادة: 0 (Glass Ionomer Cements)
0 (Micelles)
0 (Elastomers)
CPD4NFA903 (Aluminum)
Q80VPU408O (Fluorides)
YZS2RPE8LE (Strontium)
0 (ketac-molar)
0 (Polycarboxylate Cement)
0 (fuji IX)
0 (Biocompatible Materials)
تواريخ الأحداث: Date Created: 20240620 Date Completed: 20240621 Latest Revision: 20240623
رمز التحديث: 20240623
مُعرف محوري في PubMed: PMC11191184
DOI: 10.1186/s12903-024-04468-3
PMID: 38902666
قاعدة البيانات: MEDLINE
الوصف
تدمد:1472-6831
DOI:10.1186/s12903-024-04468-3