دورية أكاديمية

Feasibility assessment of catheter-free water vapor thermal therapy for treatment of benign prostatic hyperplasia.

التفاصيل البيبلوغرافية
العنوان: Feasibility assessment of catheter-free water vapor thermal therapy for treatment of benign prostatic hyperplasia.
المؤلفون: Nguyen V; Department of Urology, University of California, 9333 Genesee Avenue, Suite 320, La Jolla, CA, 92121, USA. Joie.de.vi15@gmail.com., Winograd J; Department of Urology, Weill Cornell Medical College/New York Presbyterian, New York, NY, USA., Codelia-Anjum AJ; Department of Urology, Weill Cornell Medical College/New York Presbyterian, New York, NY, USA., Zorn KC; Department of Urology, University of Montreal Hospital Center, Montreal, QC, Canada., Elterman D; Division of Urology, Department of Surgery, University Health Network, University of Toronto, Toronto, ON, Canada., Bhojani N; Department of Urology, University of Montreal Hospital Center, Montreal, QC, Canada., Bechis SK; Department of Urology, University of California, 9333 Genesee Avenue, Suite 320, La Jolla, CA, 92121, USA., Chughtai B; Department of Urology, New Hyde Park, Northwell Health, NY, USA.
المصدر: World journal of urology [World J Urol] 2024 Jun 21; Vol. 42 (1), pp. 383. Date of Electronic Publication: 2024 Jun 21.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer International Country of Publication: Germany NLM ID: 8307716 Publication Model: Electronic Cited Medium: Internet ISSN: 1433-8726 (Electronic) Linking ISSN: 07244983 NLM ISO Abbreviation: World J Urol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [Berlin ; New York] : Springer International, 1983-
مواضيع طبية MeSH: Prostatic Hyperplasia*/therapy , Feasibility Studies* , Steam*, Humans ; Male ; Middle Aged ; Aged ; Prospective Studies ; Pilot Projects ; Treatment Outcome ; Aged, 80 and over ; Adult ; Hyperthermia, Induced/methods
مستخلص: Purpose: To investigate safety and feasibility of performing water vapor thermal therapy (WVTT; Rezum, Boston Scientific, Marlborough, MA, USA) without postoperative catheterization among men with benign prostatic hyperplasia.
Methods: This is a prospective, single arm, unblinded pilot study of 20 consecutive male patients ages 40-80 who underwent WVTT at a single academic institution. All patients underwent 1 injection per lobe at the point of maximal obstruction based on visualization. Primary outcome was evaluation of voiding parameters, symptom scores, and need for catheterization at 3 day, 1, 3, and 6 month follow up compared to baseline visit 30 days prior to surgery.
Results: Mean age was 65 years (range 55-75). Mean prostate volume and PVR were 43 cc (range 30-68) and 89 cc, with 30% (n = 6) having median lobes. Patients received 2-3 treatments based on presence of bilobar versus trilobar hyperplasia. One patient (55 cc prostate, no median lobe) required catheterization for acute urinary retention on postoperative day 2. No patients required antibiotics for urinary tract infection or inpatient readmission within 30 days. Qmax significantly increased from 6 mL/s to 8, 13, 12, and 14 at 3 days, 1, 3, and 6 months (p < 0.05). IPSS decreased from 17 preoperatively to 10, 6, 7, and 8 (p < 0.05). No significant differences were noted in PVR, IIEF, MSHQ-EjD, or SF-12.
Conclusions: In well-selected men, catheter-free WVTT is feasible and improved voiding parameters and symptom scores. No changes in sexual function, infectious complications, or readmission were noted. Only 1 patient (5%) required postoperative catheterization within 30 days.
(© 2024. The Author(s).)
التعليقات: Comment in: World J Urol. 2024 Jul 29;42(1):456. doi: 10.1007/s00345-024-05163-2. (PMID: 39073576)
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فهرسة مساهمة: Keywords: Benign prostatic hyperplasia; Rezum; Water vapor thermal therapy
المشرفين على المادة: 0 (Steam)
تواريخ الأحداث: Date Created: 20240621 Date Completed: 20240621 Latest Revision: 20240730
رمز التحديث: 20240730
مُعرف محوري في PubMed: PMC11192826
DOI: 10.1007/s00345-024-05002-4
PMID: 38904777
قاعدة البيانات: MEDLINE
الوصف
تدمد:1433-8726
DOI:10.1007/s00345-024-05002-4