دورية أكاديمية
Silver-nanoparticle-modified nanocellulose synthesized by pyroligneous acid: cytotoxicity towards HaCat cells.
| العنوان: | Silver-nanoparticle-modified nanocellulose synthesized by pyroligneous acid: cytotoxicity towards HaCat cells. |
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| المؤلفون: | Medeiros LCD; Biological Chemistry and Chemometrics Research Group, Institute of Chemistry, Federal University of Rio Grande do Norte, Natal 59072-970, RN, Brazil., Sant'Anna C; Laboratory of Biotechnology-Labio, National Institute of Metrology, Quality and technology-Inmetro, Duque de Caxias 25250-020, RJ, Brazil., Ferreira VS; Laboratory of Biotechnology-Labio, National Institute of Metrology, Quality and technology-Inmetro, Duque de Caxias 25250-020, RJ, Brazil., Gasparotto LHS; Biological Chemistry and Chemometrics Research Group, Institute of Chemistry, Federal University of Rio Grande do Norte, Natal 59072-970, RN, Brazil. |
| المصدر: | Nanotechnology [Nanotechnology] 2024 Jul 02; Vol. 35 (38). Date of Electronic Publication: 2024 Jul 02. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: IOP Pub Country of Publication: England NLM ID: 101241272 Publication Model: Electronic Cited Medium: Internet ISSN: 1361-6528 (Electronic) Linking ISSN: 09574484 NLM ISO Abbreviation: Nanotechnology Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Bristol, UK : IOP Pub., c1990- |
| مواضيع طبية MeSH: | Silver*/chemistry , Metal Nanoparticles*/chemistry , Cellulose*/chemistry , Cellulose*/pharmacology , Cell Survival*/drug effects , HaCaT Cells*, Humans ; Keratinocytes/drug effects ; Keratinocytes/cytology ; Particle Size ; Cell Proliferation/drug effects ; Acetic Acid/chemistry ; Acetic Acid/pharmacology |
| مستخلص: | In the present study, pyroligneous acid, also known as wood vinegar, has been employed as reducing and stabilizing agent in the synthesis of silver nanoparticles (AgNPs) anchored on nanocellulose (NC). The idea is to confer the latter bactericidal properties for its typical uses such as in cosmetics and food-packing. It has been demonstrated that AgNPs can be directly produced onto NC in one-pot fashion while dramatically enhancing the kinetics of AgNPs synthesis (2 h for reaction completion) in comparison to the NC-less counterpart (10 days for reaction completion). Furthermore, NC allowed for a narrower size distribution of AgNPs. NC-supported and non-supported AgNPs had sizes of 5.1 ± 1.6 nm and 16.7 ± 4.62 nm, respectively. Immortalized human keratinocytes (HaCat) cells were then employed as model to evaluate the cytotoxicity of the AgNPs-NC compound. The latter was found not to impact cell proliferation at any formulation, while decreasing the viability by only 6.8% after 72 h. This study contributes to the development of more environmentally benign routes to produce nanomaterials and to the understanding of their impact on cells. (© 2024 IOP Publishing Ltd.) |
| فهرسة مساهمة: | Keywords: cytotoxicity; environmentally friendly process; nanocellulose; pyroligneous acid; silver nanoparticles |
| المشرفين على المادة: | 3M4G523W1G (Silver) 9004-34-6 (Cellulose) Q40Q9N063P (Acetic Acid) |
| تواريخ الأحداث: | Date Created: 20240621 Date Completed: 20240702 Latest Revision: 20240702 |
| رمز التحديث: | 20240703 |
| DOI: | 10.1088/1361-6528/ad5aa2 |
| PMID: | 38906121 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1361-6528 |
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| DOI: | 10.1088/1361-6528/ad5aa2 |