دورية أكاديمية
Gastrointestinal stromal tumor of the duodenum presenting with shock and massive upper and lower gastrointestinal bleeding: a case report and review of the literature.
| العنوان: | Gastrointestinal stromal tumor of the duodenum presenting with shock and massive upper and lower gastrointestinal bleeding: a case report and review of the literature. |
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| المؤلفون: | Mohamed YAE; Consultant of Gastroenterology and Endoscopy at Mahala Hepatology Teaching Center, Gharbiya, Egypt., Abdelghaffar MM; Consultant of Gastroenterology and Endoscopy at Ahmed Maher Teaching Hospital, Cairo, Egypt., Khalaf SS; Department of Biochemistry, Faculty of Pharmacy, Heliopolis University, Cairo, Egypt., Amin AF; Department of Anesthesia and ICU, Faculty of Medicine, Zagazig University, Zagazig, Egypt., Mostafa MA; Department of Anesthesia and ICU, Faculty of Medicine, Zagazig University, Zagazig, Egypt., Harb O; Department of Pathology, Faculty of Medicine, Zagazig Universit, Zagazig, Egypt. olaharb2015@gmail.com., Mohamed AH; Department of Pathology, Faculty of Medicine, Zagazig Universit, Zagazig, Egypt., Abdelfattah AR; Department of General Surgery, Faculty of Medicine, Zagazig University, Zagazig, Egypt. |
| المصدر: | Journal of medical case reports [J Med Case Rep] 2024 Jun 22; Vol. 18 (1), pp. 286. Date of Electronic Publication: 2024 Jun 22. |
| نوع المنشور: | Case Reports; Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: BioMed Central Country of Publication: England NLM ID: 101293382 Publication Model: Electronic Cited Medium: Internet ISSN: 1752-1947 (Electronic) Linking ISSN: 17521947 NLM ISO Abbreviation: J Med Case Rep Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: [London] : BioMed Central, [2007- |
| مواضيع طبية MeSH: | Gastrointestinal Stromal Tumors*/complications , Gastrointestinal Stromal Tumors*/pathology , Gastrointestinal Stromal Tumors*/diagnosis , Gastrointestinal Stromal Tumors*/surgery , Gastrointestinal Hemorrhage*/etiology , Duodenal Neoplasms*/complications , Duodenal Neoplasms*/surgery , Duodenal Neoplasms*/pathology , Shock, Hemorrhagic*/etiology, Humans ; Male ; Middle Aged ; Melena/etiology ; Hematemesis/etiology ; Gastrectomy |
| مستخلص: | Background: Due to rarity of duodenal GISTs, clinicians have few information about its clinical features, diagnosis, management and prognosis. Case Report: We report a case of promptly diagnosed duodenal GIST in a 61-year-old Egyptian man presented shocked with severe attack of hematemesis and melena. Upper gastroduodenal endoscopy was done and revealed a large ulcerating bleeding mass at first part of duodenum 4 hemo-clips were applied with good hemostasis. An exploratory laparotomy and distal gastrectomy, duodenectomy and gastrojejunostomy were performed. The morphology of the mass combined with immunohistochemistry was consistent with duodenal gastrointestinal stromal tumours (GISTs) of high risk type. The patient is on amatinib one tablet daily and he was well with no evidence of tumor recurrence. Conclusion: despite being rare, emergency presentation with sudden severe, life-threatening hemorrhagic shock duodenal GISTs might be a cause of potentially lethal massive combined upper and lower gastrointestinal bleeding which is the key feature of this rare and challenging tumor. (© 2024. The Author(s).) |
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| فهرسة مساهمة: | Keywords: Bleeding; Duodenal GIST; Endoscopy |
| تواريخ الأحداث: | Date Created: 20240621 Date Completed: 20240621 Latest Revision: 20240703 |
| رمز التحديث: | 20240704 |
| مُعرف محوري في PubMed: | PMC11193304 |
| DOI: | 10.1186/s13256-024-04597-x |
| PMID: | 38907357 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1752-1947 |
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| DOI: | 10.1186/s13256-024-04597-x |