دورية أكاديمية
Burden of delirium on mortality and healthcare resource utilization in geriatric patients hospitalized for inflammatory bowel disease.
العنوان: | Burden of delirium on mortality and healthcare resource utilization in geriatric patients hospitalized for inflammatory bowel disease. |
---|---|
المؤلفون: | Aldiabat M; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Harvard University, Boston, Massachusetts, USA.; Department of Medicine, Washington University in St. Louis, St. Louis, Missouri, USA., Aleyadeh W; Department of Medicine, Akron General Hospital, Akron, Ohio, USA., Rana T; Department of Medicine, Allegheny Health Network, Pittsburgh, Pennsylvania, USA., Ta'ani OA; Department of Medicine, Allegheny Health Network, Pittsburgh, Pennsylvania, USA., Alahmad M; Department of Medicine, University of Missouri-Columbia, Columbia, Missouri, USA., Ayoub M; Department of Medicine, Washington University in St. Louis, St. Louis, Missouri, USA., Jaber F; Department of Medicine, University of Missouri-Kansas City, Kansas City, Missouri, USA., Obeidat A; Presbyterian Health System, Albuquerque, New Mexico, USA., Numan L; Division of Gastroenterology, SSM Health Saint Louis University Hospital, St. Louis, Missouri, USA., Manvar A; Division of Gastroenterology, NYU Langone Health, Mineola, New York, USA., Alhuneafat L; Department of Cardiovascular Disease, University of Minnesota, Minneapolis, Minnesota, USA. |
المصدر: | Proceedings (Baylor University. Medical Center) [Proc (Bayl Univ Med Cent)] 2024 Apr 22; Vol. 37 (4), pp. 509-515. Date of Electronic Publication: 2024 Apr 22 (Print Publication: 2024). |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Baylor Research Foundation Country of Publication: United States NLM ID: 9302033 Publication Model: eCollection Cited Medium: Print ISSN: 0899-8280 (Print) Linking ISSN: 08998280 NLM ISO Abbreviation: Proc (Bayl Univ Med Cent) Subsets: PubMed not MEDLINE |
أسماء مطبوعة: | Original Publication: Dallas, Tex. : Baylor Research Foundation, |
مستخلص: | Background: Delirium is prevalent in elderly patients, linked to elevated mortality rates, heightened healthcare resource use, and caregiver burden. Inflammatory bowel disease (IBD) poses various delirium risk factors, yet the impact on geriatric IBD patient outcomes remains unexplored. Methods: Using 2016-2019 National Inpatient Sample data, we identified ≥65-year-old patients admitted for IBD (Crohn's, ulcerative colitis) management stratified by delirium presence as a secondary diagnosis. The study aimed to assess delirium's impact on geriatric IBD patient outcomes. Results: Among 67,534 elderly IBD admissions, 0.7% (470) developed delirium. The delirium group had a 4.8-fold increase in in-hospital mortality risk (odds ratio 4.80, P < 0.001, 95% confidence interval [CI] 1.94-11.8). IBD patients with delirium experienced prolonged length of stay (adjusted mean difference 5.15 days, 95% CI 3.24-7.06, P < 0.001) and increased care costs (adjusted mean difference $48,328, 95% CI $26,485-$70,171, P < 0.001) compared to those without delirium. Conclusion: Elderly IBD patients with delirium face higher mortality risk, prolonged hospitalization, and increased healthcare costs. Clinicians should recognize delirium's detrimental effects in this vulnerable group and adhere to preventive protocols for improved care. Competing Interests: The authors report no funding or conflicts of interest. (Copyright © 2024 Baylor University Medical Center.) |
References: | Aliment Pharmacol Ther. 2022 Sep;56(5):831-843. (PMID: 35781292) J Alzheimers Dis. 2021;80(4):1471-1478. (PMID: 33720902) Clin Geriatr Med. 2020 May;36(2):183-199. (PMID: 32222295) BMC Geriatr. 2005 Apr 13;5:6. (PMID: 15826320) BMJ. 2021 Jun 8;373:n1007. (PMID: 34103334) Cochrane Database Syst Rev. 2003;(4):CD004514. (PMID: 14584018) Front Hum Neurosci. 2019 Apr 03;13:107. (PMID: 31001097) Front Immunol. 2023 Jan 27;14:1087571. (PMID: 36776896) Nat Rev Neurol. 2009 Apr;5(4):210-20. (PMID: 19347026) Arch Intern Med. 2008 Jan 14;168(1):27-32. (PMID: 18195192) JAMA Neurol. 2020 Nov 1;77(11):1373-1381. (PMID: 32658246) United European Gastroenterol J. 2017 Jun;5(4):579-587. (PMID: 28588890) Neuropsychiatr Dis Treat. 2015 Aug 07;11:2033-9. (PMID: 26300642) Nutrients. 2023 Aug 25;15(17):. (PMID: 37686760) Clin Colon Rectal Surg. 2019 Jan;32(1):33-40. (PMID: 30647544) Neurogastroenterol Motil. 2017 Oct;29(10):1-10. (PMID: 28560758) Semin Respir Crit Care Med. 2021 Feb;42(1):112-126. (PMID: 32746469) Psychogeriatrics. 2018 Jul;18(4):268-275. (PMID: 30133935) BMJ. 2007 Oct 20;335(7624):806-8. (PMID: 17947786) Nutrition. 2021 Jun;86:111182. (PMID: 33611107) Inflamm Bowel Dis. 2017 Jun;23(6):882-893. (PMID: 28375885) Inflamm Bowel Dis. 2011 Aug;17(8):1769-77. (PMID: 21744432) J Neurosci. 2015 Mar 25;35(12):4942-52. (PMID: 25810524) N Engl J Med. 2013 Oct 3;369(14):1306-16. (PMID: 24088092) Gut. 2021 Jan;70(1):85-91. (PMID: 32576641) Front Med (Lausanne). 2022 Nov 30;9:1004407. (PMID: 36530904) World J Gastrointest Pharmacol Ther. 2016 Feb 6;7(1):51-65. (PMID: 26855812) J Crohns Colitis. 2011 Feb;5(1):5-13. (PMID: 21272797) Curr Treat Options Gastroenterol. 2016 Sep;14(3):285-304. (PMID: 27387455) |
فهرسة مساهمة: | Keywords: Geriatrics; inflammatory bowel disease; outcomes research |
تواريخ الأحداث: | Date Created: 20240624 Latest Revision: 20240625 |
رمز التحديث: | 20240625 |
مُعرف محوري في PubMed: | PMC11188812 |
DOI: | 10.1080/08998280.2024.2342106 |
PMID: | 38910812 |
قاعدة البيانات: | MEDLINE |
تدمد: | 0899-8280 |
---|---|
DOI: | 10.1080/08998280.2024.2342106 |