دورية أكاديمية
Oncologist-Reported Barriers and Facilitators to Offering Cancer Clinical Trials to Their Patients.
| العنوان: | Oncologist-Reported Barriers and Facilitators to Offering Cancer Clinical Trials to Their Patients. |
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| المؤلفون: | Castillo BS; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Boehmer L; Association of Community Cancer Centers, Rockville, MD 20850, USA., Schrag J; Whitman-Walker Institute, Washington, DC 20009, USA., Howson A; Thistle Editorial LLC., Snoqualmie, WA 98065, USA., Oyer R; Ann B. Barshinger Cancer Institute, Penn Medicine Lancaster General Health, Lancaster, PA 17601, USA., Pierce L; Rogel Comprehensive Cancer Center at the University of Michigan, Ann Arbor, MI 48109, USA., Barrett NJ; Duke Clinical and Translational Science Institute and Duke Cancer Institute, Durham, NC 27701, USA., Guerra CE; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA.; Leonard Davis Institute, University of Pennsylvania, Philadelphia, PA 19104, USA. |
| المصدر: | Current oncology (Toronto, Ont.) [Curr Oncol] 2024 May 28; Vol. 31 (6), pp. 3017-3029. Date of Electronic Publication: 2024 May 28. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 9502503 Publication Model: Electronic Cited Medium: Internet ISSN: 1718-7729 (Electronic) Linking ISSN: 11980052 NLM ISO Abbreviation: Curr Oncol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2021- : Basel, Switzerland : MDPI Original Publication: Toronto : Multimed, c1994- |
| مواضيع طبية MeSH: | Clinical Trials as Topic* , Oncologists* , Neoplasms*/therapy, Humans ; Female ; Male ; Middle Aged ; Medical Oncology/methods |
| مستخلص: | NCCN guidelines indicate that cancer clinical trials (CCTs) are the best management for patients with cancer. However, only 5% of patients enroll in them. We examined oncologists' perceived barriers and facilitators to discussing CCTs. This qualitative study was part of the ASCO-ACCC Initiative to Increase Racial and Ethnic Diversity in Clinical Trials. Barriers and facilitators at the system, trial, provider, and patient levels were examined. To achieve triangulation, patient encounters were reviewed using chart-stimulated recall (CSR) methods, thereby obtaining a valid assessment of physician performance. Ten oncology providers participated in this study. Nine were oncologists, and one was a clinical research coordinator; five were female; four were White; three were Asian; and three were Black. Barriers to offering CCTs were a lack of trial availability; ineligibility; a lack of knowledge; assumptions about patient interest, benefits, or harms; patient's disease factors; and negative attitudes. Facilitators of offering CCTs were a physical space to discuss trials; greater trial availability; a systematic approach to offering trials; patient factors; patients seeking trials; a lack of comorbidities; patients being younger in age; patients being aware of, asking about, or hearing of trials from their surgeon; and higher levels of altruism. Many of the cited barriers are addressable with the cited facilitators. A larger study is needed to generalize and validate these findings. |
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| فهرسة مساهمة: | Keywords: barrier; cancer; clinical trials; disparities; facilitator; qualitative research |
| تواريخ الأحداث: | Date Created: 20240626 Date Completed: 20240626 Latest Revision: 20240628 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC11202609 |
| DOI: | 10.3390/curroncol31060230 |
| PMID: | 38920714 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1718-7729 |
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| DOI: | 10.3390/curroncol31060230 |