دورية أكاديمية
أعرض في EDS

Comparative Analysis of Micro-Computed Tomography and 3D Micro-Ultrasound for Measurement of the Mouse Aorta.

التفاصيل البيبلوغرافية
العنوان: Comparative Analysis of Micro-Computed Tomography and 3D Micro-Ultrasound for Measurement of the Mouse Aorta.
المؤلفون: Alenezi HA; Leeds Institute for Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds LS2 9JT, UK., Hemmings KE; Leeds Institute for Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds LS2 9JT, UK., Kandavelu P; Leeds Institute for Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds LS2 9JT, UK., Koch-Paszkowski J; Leeds Institute for Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds LS2 9JT, UK., Bailey MA; Leeds Institute for Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds LS2 9JT, UK.
المصدر: Journal of imaging [J Imaging] 2024 Jun 17; Vol. 10 (6). Date of Electronic Publication: 2024 Jun 17.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101698819 Publication Model: Electronic Cited Medium: Internet ISSN: 2313-433X (Electronic) Linking ISSN: 2313433X NLM ISO Abbreviation: J Imaging Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI, [2015]-
مستخلص: Aortic aneurysms, life-threatening and often undetected until they cause sudden death, occur when the aorta dilates beyond 1.5 times its normal size. This study used ultrasound scans and micro-computed tomography to monitor and measure aortic volume in preclinical settings, comparing it to the well-established measurement using ultrasound scans. The reproducibility of measurements was also examined for intra- and inter-observer variability, with both modalities used on 8-week-old C57BL6 mice. For inter-observer variability, the μCT (micro-computed tomography) measurements for the thoracic, abdominal, and whole aorta between observers were highly consistent, showing a strong positive correlation (R 2 = 0.80, 0.80, 0.95, respectively) and no significant variability ( p -value: 0.03, 0.03, 0.004, respectively). The intra-observer variability for thoracic, abdominal, and whole aorta scans demonstrated a significant positive correlation (R 2 = 0.99, 0.96, 0.87, respectively) and low variability ( p -values = 0.0004, 0.002, 0.01, respectively). The comparison between μCT and USS (ultrasound) in the suprarenal and infrarenal aorta showed no significant difference ( p -value = 0.20 and 0.21, respectively). μCT provided significantly higher aortic volume measurements compared to USS. The reproducibility of USS and μCT measurements was consistent, showing minimal variance among observers. These findings suggest that μCT is a reliable alternative for comprehensive aortic phenotyping, consistent with clinical findings in human data.
References: Ultrasound Med Biol. 2007 Oct;33(10):1552-60. (PMID: 17602826)
Eur J Vasc Endovasc Surg. 2014 Apr;47(4):367-73. (PMID: 24491283)
PLoS One. 2017 Jun 5;12(6):e0178682. (PMID: 28582441)
Circulation. 2008 Apr 8;117(14):1883-9. (PMID: 18391122)
J Emerg Med. 2016 Apr;50(4):643-50.e1. (PMID: 26830361)
J Thorac Imaging. 2009 Aug;24(3):223-6. (PMID: 19704327)
Aorta (Stamford). 2021 Dec;9(6):215-220. (PMID: 34963161)
Chonnam Med J. 2018 Sep;54(3):143-152. (PMID: 30288369)
J Vasc Surg. 2001 Jan;33(1):42-50. (PMID: 11137922)
J Thorac Cardiovasc Surg. 2021 Feb;161(2):498-511.e1. (PMID: 31982126)
Lancet. 2005 Apr 30-May 6;365(9470):1577-89. (PMID: 15866312)
Arterioscler Thromb Vasc Biol. 2019 Dec;39(12):e247-e252. (PMID: 31770033)
Eur J Vasc Endovasc Surg. 2009 May;37(5):531-7. (PMID: 19297214)
Phys Med. 2014 Sep;30(6):619-34. (PMID: 24974176)
Nat Rev Cardiol. 2021 May;18(5):331-348. (PMID: 33353985)
Biomedicines. 2022 Jan 02;10(1):. (PMID: 35052774)
Eur J Vasc Endovasc Surg. 2004 Aug;28(2):158-67. (PMID: 15234697)
Prog Cardiovasc Dis. 2021 Mar-Apr;65:34-43. (PMID: 33831398)
J Vasc Surg. 2003 Sep;38(3):466-71; discussion 471-2. (PMID: 12947257)
Ann Vasc Surg. 2001 Mar;15(2):155-62. (PMID: 11265078)
Mayo Clin Proc. 2009 May;84(5):465-81. (PMID: 19411444)
Crit Care Med. 2007 Aug;35(8 Suppl):S392-400. (PMID: 17667464)
Ann N Y Acad Sci. 2006 Nov;1085:117-32. (PMID: 17182928)
Echo Res Pract. 2019 Dec 05;7(1):R1-R10. (PMID: 32015897)
Med Phys. 2010 Dec;37(12):6421-42. (PMID: 21302799)
معلومات مُعتمدة: (FS/18/12/33270). British Heart Foundation Fellowship; 11050779 Kuwait Ministry of Health (MOH) and University of Leeds
فهرسة مساهمة: Keywords: Micro-CT; aortic aneurysm; preclinical imaging; ultrasound
تواريخ الأحداث: Date Created: 20240626 Latest Revision: 20240628
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC11204474
DOI: 10.3390/jimaging10060145
PMID: 38921622
قاعدة البيانات: MEDLINE
الوصف
تدمد:2313-433X
DOI:10.3390/jimaging10060145