دورية أكاديمية
In vitro effect of TiF4/NaF solution on the development of radiation-induced dentin caries.
| العنوان: | In vitro effect of TiF4/NaF solution on the development of radiation-induced dentin caries. |
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| المؤلفون: | Souza BM; Universidade de São Paulo, Faculdade de Odontologia de Bauru, Departamento de Ciências Biológicas,Bauru, São Paulo, Brasil., Francisco EL; Universidade de São Paulo, Faculdade de Odontologia de Bauru, Departamento de Ciências Biológicas,Bauru, São Paulo, Brasil., Braga AS; Universidade de São Paulo, Faculdade de Odontologia de Bauru, Departamento de Ciências Biológicas,Bauru, São Paulo, Brasil., Santos PSDS; Universidade de São Paulo, Faculdade d e Odontologia de Bauru, Departamento de Cirurgia, Estomatologia, Patologia e Radiologia, ,Bauru, São Paulo, Brasil., Buzalaf MAR; Universidade de São Paulo, Faculdade de Odontologia de Bauru, Departamento de Ciências Biológicas,Bauru, São Paulo, Brasil., Magalhães AC; Universidade de São Paulo, Faculdade de Odontologia de Bauru, Departamento de Ciências Biológicas,Bauru, São Paulo, Brasil. |
| المصدر: | Journal of applied oral science : revista FOB [J Appl Oral Sci] 2024 Jun 24; Vol. 32, pp. e20240024. Date of Electronic Publication: 2024 Jun 24 (Print Publication: 2024). |
| نوع المنشور: | Journal Article; Evaluation Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Faculdade de Odontologia de Bauru, USP Country of Publication: Brazil NLM ID: 101189774 Publication Model: eCollection Cited Medium: Internet ISSN: 1678-7765 (Electronic) Linking ISSN: 16787757 NLM ISO Abbreviation: J Appl Oral Sci Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Bauru, SP : Faculdade de Odontologia de Bauru, USP, [2003]- |
| مواضيع طبية MeSH: | Sodium Fluoride*/pharmacology , Dentin*/drug effects , Dentin*/radiation effects , Dentin*/microbiology , Dental Caries*/prevention & control , Dental Caries*/microbiology , Biofilms*/drug effects , Fluorides*/pharmacology , Saliva*/microbiology , Saliva*/chemistry , Saliva*/drug effects , Streptococcus mutans*/drug effects, Cattle ; Animals ; Time Factors ; Analysis of Variance ; Microradiography ; Cariostatic Agents/pharmacology ; Reproducibility of Results ; Lactobacillus/drug effects ; Colony Count, Microbial ; Tooth Demineralization/prevention & control ; Humans ; Materials Testing ; Reference Values ; Treatment Outcome ; Statistics, Nonparametric ; Titanium |
| مستخلص: | Objective: To evaluate the protective effect of an experimental solution containing TiF4/NaF on the development of radiation-induced dentin caries lesions. Methodology: bovine root samples were irradiated (70Gy) and distributed as following (n=12/group): Commercial Saliva (BioXtra), NaF (500 ppm F-), TiF4 (500 ppm F), TiF4/NaF (TiF4: 300 ppm F-, NaF: 190 ppm F-), and Phosphate buffer solution (PBS, negative control). Biofilm was produced using biofilm from irradiated patients and McBain saliva (0.2% of sucrose, at 37oC and 5% CO2) for five days. The treatments were applied 1x/day. Colony-forming units (CFU) were counted and demineralization was quantified by transversal microradiography. The ANOVA/Tukey test was applied for all parameters. Results: All treatments reduced CFU for total microorganisms. TiF4 reduced Lactobacillus sp. (7.04±0.26 log10 CFU/mL) and mutans streptococci (7.18±0.28) CFU the most, when compared to PBS (7.58±0.21 and 7.75±0.17) and followed by NaF (7.12±0.31 and 7.34±0.22) and TiF4/NaF (7.16±0.35 and 7.29± 0.29). TiF4 and Commercial saliva showed the lowest integrated mineral loss (ΔZ-vol%.mm) (1977±150 and 2062±243, respectively) when compared to PBS (4540±335), followed by NaF (2403±235) and TiF4/NaF (2340±200). Commercial saliva was the only to significantly reduce mineral loss (LD-µm) (111±25) compared to PBS (153±24).Mean mineral loss (R-vol%) decreased by 35.2% for TiF4 (18.2±3.3) when compared to PBS (28.1±2.9) Conclusion: TiF4/NaF has a comparable anti-cariogenic effect to TiF4 and Commercial saliva under the model in this study. |
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| المشرفين على المادة: | 8ZYQ1474W7 (Sodium Fluoride) T08RW8YRG1 (titanium tetrafluoride) Q80VPU408O (Fluorides) 0 (Cariostatic Agents) D1JT611TNE (Titanium) |
| تواريخ الأحداث: | Date Created: 20240626 Date Completed: 20240626 Latest Revision: 20240628 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC11182639 |
| DOI: | 10.1590/1678-7757-2024-0024 |
| PMID: | 38922242 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1678-7765 |
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| DOI: | 10.1590/1678-7757-2024-0024 |