دورية أكاديمية
Hotspot shelters stimulate frog resistance to chytridiomycosis.
| العنوان: | Hotspot shelters stimulate frog resistance to chytridiomycosis. |
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| المؤلفون: | Waddle AW; Melbourne Veterinary School, University of Melbourne, Werribee, Victoria, Australia. anthony.waddle@mq.edu.au.; School of Natural Sciences, Macquarie University, Sydney, New South Wales, Australia. anthony.waddle@mq.edu.au.; Applied BioSciences, Macquarie University, Sydney, New South Wales, Australia. anthony.waddle@mq.edu.au., Clulow S; School of Natural Sciences, Macquarie University, Sydney, New South Wales, Australia.; Centre for Conservation Ecology and Genomics, Institute for Applied Ecology, University of Canberra, Bruce, Australian Capital Territory, Australia., Aquilina A; Melbourne Veterinary School, University of Melbourne, Werribee, Victoria, Australia.; School of Natural Sciences, Macquarie University, Sydney, New South Wales, Australia., Sauer EL; Department of Biological Sciences, University of Arkansas, Fayetteville, AR, USA., Kaiser SW; School of Natural Sciences, Macquarie University, Sydney, New South Wales, Australia., Miller C; School of Mathematics and Statistics, University of Melbourne, Parkville, Victoria, Australia.; Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand., Flegg JA; School of Mathematics and Statistics, University of Melbourne, Parkville, Victoria, Australia., Campbell PT; Department of Infectious Diseases, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Gallagher H; School of Natural Sciences, Macquarie University, Sydney, New South Wales, Australia., Dimovski I; School of Natural Sciences, Macquarie University, Sydney, New South Wales, Australia., Lambreghts Y; School of Natural Sciences, Macquarie University, Sydney, New South Wales, Australia.; School of Natural Sciences, University of Tasmania, Hobart, Tasmania, Australia., Berger L; Melbourne Veterinary School, University of Melbourne, Werribee, Victoria, Australia., Skerratt LF; Melbourne Veterinary School, University of Melbourne, Werribee, Victoria, Australia., Shine R; School of Natural Sciences, Macquarie University, Sydney, New South Wales, Australia. |
| المصدر: | Nature [Nature] 2024 Jul; Vol. 631 (8020), pp. 344-349. Date of Electronic Publication: 2024 Jun 26. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Basingstoke : Nature Publishing Group Original Publication: London, Macmillan Journals ltd. |
| مواضيع طبية MeSH: | Anura*/immunology , Anura*/microbiology , Anura*/physiology , Chytridiomycota*/immunology , Chytridiomycota*/pathogenicity , Chytridiomycota*/physiology , Disease Resistance*/immunology , Disease Resistance*/physiology , Disease Resistance*/radiation effects , Endangered Species* , Mycoses*/veterinary , Mycoses*/microbiology , Mycoses*/immunology , Refugium*, Animals ; Body Temperature/immunology ; Body Temperature/physiology ; Body Temperature/radiation effects ; Ecosystem ; Sunlight ; Animals, Wild/immunology ; Animals, Wild/microbiology ; Animals, Wild/physiology ; Introduced Species |
| مستخلص: | Many threats to biodiversity cannot be eliminated; for example, invasive pathogens may be ubiquitous. Chytridiomycosis is a fungal disease that has spread worldwide, driving at least 90 amphibian species to extinction, and severely affecting hundreds of others 1-4 . Once the disease spreads to a new environment, it is likely to become a permanent part of that ecosystem. To enable coexistence with chytridiomycosis in the field, we devised an intervention that exploits host defences and pathogen vulnerabilities. Here we show that sunlight-heated artificial refugia attract endangered frogs and enable body temperatures high enough to clear infections, and that having recovered in this way, frogs are subsequently resistant to chytridiomycosis even under cool conditions that are optimal for fungal growth. Our results provide a simple, inexpensive and widely applicable strategy to buffer frogs against chytridiomycosis in nature. The refugia are immediately useful for the endangered species we tested and will have broader utility for amphibian species with similar ecologies. Furthermore, our concept could be applied to other wildlife diseases in which differences in host and pathogen physiologies can be exploited. The refugia are made from cheap and readily available materials and therefore could be rapidly adopted by wildlife managers and the public. In summary, habitat protection alone cannot protect species that are affected by invasive diseases, but simple manipulations to microhabitat structure could spell the difference between the extinction and the persistence of endangered amphibians. (© 2024. The Author(s), under exclusive licence to Springer Nature Limited.) |
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| تواريخ الأحداث: | Date Created: 20240626 Date Completed: 20240710 Latest Revision: 20240711 |
| رمز التحديث: | 20240712 |
| DOI: | 10.1038/s41586-024-07582-y |
| PMID: | 38926575 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1476-4687 |
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| DOI: | 10.1038/s41586-024-07582-y |