دورية أكاديمية
Megastudy shows that reminders boost vaccination but adding free rides does not.
| العنوان: | Megastudy shows that reminders boost vaccination but adding free rides does not. |
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| المؤلفون: | Milkman KL; Department of Operations, Information and Decisions, The Wharton School, University of Pennsylvania, Philadelphia, PA, USA. kmilkman@wharton.upenn.edu., Ellis SF; Behavior Change for Good Initiative, The Wharton School and the School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA., Gromet DM; Behavior Change for Good Initiative, The Wharton School and the School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA., Jung Y; Behavior Change for Good Initiative, The Wharton School and the School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA., Luscher AS; Behavior Change for Good Initiative, The Wharton School and the School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA., Mobarak RS; Department of Agricultural and Resource Economics, University of Maryland, College Park, MD, USA., Paxson MK; Behavior Change for Good Initiative, The Wharton School and the School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA., Silvera Zumaran RA; Behavior Change for Good Initiative, The Wharton School and the School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA., Kuan R; Department of Operations, Information and Decisions, The Wharton School, University of Pennsylvania, Philadelphia, PA, USA., Berman R; Department of Marketing, The Wharton School, University of Pennsylvania, Philadelphia, PA, USA., Lewis NA Jr; Department of Communication, Cornell University, Ithaca, NY, USA., List JA; Department of Economics, University of Chicago, Chicago, IL, USA., Patel MS; Clinical Transformation and Behavioral Insights, Ascension Health, St Louis, MO, USA., Van den Bulte C; Department of Marketing, The Wharton School, University of Pennsylvania, Philadelphia, PA, USA., Volpp KG; Penn Center for Health Incentives and Behavioral Economics, Departments of Medical Ethics and Health Policy and Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Beauvais MV; CVS Health, Woonsocket, RI, USA., Bellows JK; CVS Health, Woonsocket, RI, USA., Marandola CA; CVS Health, Woonsocket, RI, USA., Duckworth AL; Department of Operations, Information and Decisions, The Wharton School, University of Pennsylvania, Philadelphia, PA, USA.; Department of Psychology, University of Pennsylvania, Philadelphia, PA, USA. |
| المصدر: | Nature [Nature] 2024 Jul; Vol. 631 (8019), pp. 179-188. Date of Electronic Publication: 2024 Jun 26. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Basingstoke : Nature Publishing Group Original Publication: London, Macmillan Journals ltd. |
| مواضيع طبية MeSH: | COVID-19*/prevention & control , COVID-19 Vaccines*/administration & dosage , Immunization, Secondary*/statistics & numerical data , Reminder Systems*/classification , Reminder Systems*/statistics & numerical data , Transportation*/economics , Transportation*/methods , Vaccination*/statistics & numerical data, Adult ; Female ; Humans ; Male ; Middle Aged ; Evidence-Based Practice ; Health Education/methods ; Health Education/statistics & numerical data ; Health Policy/trends ; Influenza Vaccines/administration & dosage ; Pharmacies/statistics & numerical data ; Text Messaging/statistics & numerical data ; Time Factors ; United States |
| مستخلص: | Encouraging routine COVID-19 vaccinations is likely to be a crucial policy challenge for decades to come. To avert hundreds of thousands of unnecessary hospitalizations and deaths, adoption will need to be higher than it was in the autumn of 2022 or 2023, when less than one-fifth of Americans received booster vaccines 1,2 . One approach to encouraging vaccination is to eliminate the friction of transportation hurdles. Previous research has shown that friction can hinder follow-through 3 and that individuals who live farther from COVID-19 vaccination sites are less likely to get vaccinated 4 . However, the value of providing free round-trip transportation to vaccination sites is unknown. Here we show that offering people free round-trip Lyft rides to pharmacies has no benefit over and above sending them behaviourally informed text messages reminding them to get vaccinated. We determined this by running a megastudy with millions of CVS Pharmacy patients in the United States testing the effects of (1) free round-trip Lyft rides to CVS Pharmacies for vaccination appointments and (2) seven different sets of behaviourally informed vaccine reminder messages. Our results suggest that offering previously vaccinated individuals free rides to vaccination sites is not a good investment in the United States, contrary to the high expectations of both expert and lay forecasters. Instead, people in the United States should be sent behaviourally informed COVID-19 vaccination reminders, which increased the 30-day COVID-19 booster uptake by 21% (1.05 percentage points) and spilled over to increase 30-day influenza vaccinations by 8% (0.34 percentage points) in our megastudy. More rigorous testing of interventions to promote vaccination is needed to ensure that evidence-based solutions are deployed widely and that ineffective but intuitively appealing tools are discontinued. (© 2024. The Author(s).) |
| References: | CDC. COVID-19 Vaccinations in the United States, County. Centers for Disease Control and Prevention https://data.cdc.gov/Vaccinations/COVID-19-Vaccinations-in-the-United-States-County/8xkx-amqh (2023). CDC. Weekly COVID-19 Vaccination Dashboard. Centers for Disease Control and Prevention https://www.cdc.gov/vaccines/imz-managers/coverage/covidvaxview/interactive/vaccination-dashboard.html (2024). Thaler, R. H. & Sunstein, C. R. Nudge: The Final Edition (Yale Univ. Press, 2021). Mazar, A., Jaro, D., Tomaino, G., Carmon, Z. & Wood, W. Distance to vaccine sites is tied to decreased COVID-19 vaccine uptake. PNAS Nexus 2, pgad411 (2023). (PMID: 3809461510718641) Steele, M. K. et al. Estimated number of COVID-19 infections, hospitalizations, and deaths prevented among vaccinated persons in the US, December 2020 to September 2021. JAMA Netw. Open 5, e2220385 (2022). (PMID: 357930859260489) CDC. COVID-19 Vaccinations in the United States. Centers for Disease Control and Prevention https://covid.cdc.gov/covid-data-tracker (2023). Moreira, E. D. et al. Safety and efficacy of a third dose of BNT162b2 Covid-19 vaccine. N. Engl. J. Med. 386, 1910–1921 (2022). (PMID: 35320659) Thomas, S. J. et al. Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine through 6 Months. N. Engl. J. Med. 385, 1761–1773 (2021). (PMID: 34525277) CDC. Previous COVID-19 forecasts: deaths–2023. Centers for Disease Control and Prevention https://www.cdc.gov/coronavirus/2019-ncov/science/forecasting/forecasting-us-previous-2023.html (2023). FDA. Future vaccination regimens addressing COVID-19. US Food and Drug Administration https://www.fda.gov/media/164699/download (2023). Lee, J. T. et al. Employer requirements and COVID-19 vaccination and attitudes among healthcare personnel in the U.S.: findings from national immunization survey adult COVID module, August–September 2021. Vaccine 40, 7476–7482 (2022). (PMID: 359410379234000) Mello, M. M. et al. Effectiveness of vaccination mandates in improving uptake of COVID-19 vaccines in the USA. Lancet 400, 535–538 (2022). (PMID: 358170789270060) The White House. White House Report: Vaccination requirements are helping vaccinate more people, protect Americans from COVID-19, and strengthen the economy. The White House https://www.whitehouse.gov/wp-content/uploads/2021/10/Vaccination-Requirements-Report.pdf (2021). Kirzinger, A., Kearney, A., Hamel, L. & Brodie, M. KFF COVID-19 Vaccine Monitor: The increasing importance of partisanship in predicting COVID-19 vaccination status. KFF https://www.kff.org/coronavirus-covid-19/poll-finding/importance-of-partisanship-predicting-vaccination-status/ (2021). Jacobson, M., Chang, T. Y., Shah, M., Pramanik, R. & Shah, S. B. Can financial incentives and other nudges increase COVID-19 vaccinations among the vaccine hesitant? A randomized trial. Vaccine 40, 6235–6242 (2022). (PMID: 361379009424519) Thirumurthy, H., Milkman, K. L., Volpp, K. G., Buttenheim, A. M. & Pope, D. G. Association between statewide financial incentive programs and COVID-19 vaccination rates. PLoS ONE 17, e0263425 (2022). (PMID: 353538158966995) Chang, T. Y. et al. Reminders, but not monetary incentives, increase COVID-19 booster uptake. Proc. Natl Acad. Sci. USA 120, e2302725120 (2023). (PMID: 3748710110400997) Law, A. C., Peterson, D., Walkey, A. J. & Bosch, N. A. Lottery-based incentives and COVID-19 vaccination rates in the US. JAMA Intern. Med. 182, 235–237 (2022). (PMID: 349821118728655) Dai, H. et al. Behavioural nudges increase COVID-19 vaccinations. Nature 597, 404–409 (2021). (PMID: 343402428443442) Milkman, K. L. et al. A megastudy of text-based nudges encouraging patients to get vaccinated at an upcoming doctor’s appointment. Proc. Natl Acad. Sci. USA 118, e2101165118 (2021). (PMID: 339269938157982) Milkman, K. L. et al. A 680,000-person megastudy of nudges to encourage vaccination in pharmacies. Proc. Natl Acad. Sci. USA 119, e2115126119 (2022). (PMID: 351058098833156) Johnson, E. J. & Goldstein, D. Do defaults save lives? Science 302, 1338–1339 (2003). (PMID: 14631022) Madrian, B. C. & Shea, D. F. The power of suggestion: inertia in 401(k) participation and savings behavior. Q. J. Econ. 116, 1149–1187 (2001). Bettinger, E. P., Long, B. T., Oreopoulos, P. & Sanbonmatsu, L. The role of application assistance and information in college decisions: results from the H&R Block FAFSA experiment. Q. J. Econ. 127, 1205–1242 (2012). Beshears, J., Choi, J. J., Laibson, D. I., Madrian, B. C. & Reynolds, G. I. Vaccination rates are associated with functional proximity but not base proximity of vaccination clinics. Med. Care 54, 578–583 (2016). (PMID: 271772954868403) Feldman, N. Why Black and Latino people still lag on COVID vaccines—and how to fix it. NPR (26 April 2021). Associated Press. COVID-19 vaccine bypasses some older adults. Fox News (4 March 2021). Mueller, B. People with disabilities have a tougher time getting COVID vaccines, the C.D.C. reports. The New York Times (30 September 2021). Lyft. Vaccines for all: announcing free or discounted rides to vaccination sites. Lyft https://www.lyft.com/blog/posts/vaccines-for-all-announcing-free-rides-for-anyone-getting-a-shot (2021). rabbittransit. FREE rides to COVID-19 vaccination sites. rabbittransit https://www.rabbittransit.org/covid-19-vaccinations/ (2021). Uber. 10 million free or discounted rides for vaccinations. Uber https://www.uber.com/us/en/impact/rides-for-vaccines/ (2021). US Department of Transportation. U.S. Department of Transportation thanks transit agencies for helping Americans access COVID-19 vaccination sites nationwide and encourages more to step up as part of national month of action. US Department of Transportation https://www.transportation.gov/briefing-room/us-department-transportation-thanks-transit-agencies-helping-americans-access-covid (2021). Siddiqui, S. & Armour, S. Uber, Lyft to provide free rides to Covid-19 vaccine sites until July 4. Wall Street Journal (11 May 2021). Ericson, K. M. M. Forgetting we forget: overconfidence and memory. J. Eur. Econ. Assoc. 9, 43–60 (2011). (PMID: 367787239912350) Gravert, C. in Behavioral Science in the Wild (eds Mažar, N. & Soman, D.) 120–132 (Univ. Toronto Press, 2022). Regan, A. K., Bloomfield, L., Peters, I. & Effler, P. V. Randomized controlled trial of text message reminders for increasing influenza vaccination. Ann. Fam. Med. 15, 507–514 (2017). (PMID: 291334885683861) Vervloet, M. et al. The effectiveness of interventions using electronic reminders to improve adherence to chronic medication: a systematic review of the literature. J. Am. Med. Inform. Assoc. 19, 696–704 (2012). (PMID: 225340823422829) Karlan, D., McConnell, M., Mullainathan, S. & Zinman, J. Getting to the top of mind: how reminders increase saving. Manag. Sci. 62, 3393–3411 (2016). Austin, J., Sigurdsson, S. O. & Rubin, Y. S. An examination of the effects of delayed versus immediate prompts on safety belt use. Environ. Behav. 38, 140–149 (2006). Fishbane, A., Ouss, A. & Shah, A. K. Behavioral nudges reduce failure to appear for court. Science 370, eabb6591 (2020). (PMID: 33033154) Chapman, G. B., Li, M., Colby, H. & Yoon, H. Opting in vs opting out of influenza vaccination. JAMA 304, 43–44 (2010). (PMID: 20606147) Milkman, K. L., Beshears, J., Choi, J. J., Laibson, D. & Madrian, B. C. Using implementation intentions prompts to enhance influenza vaccination rates. Proc. Natl Acad. Sci. USA 108, 10415–10420 (2011). (PMID: 216702833127912) Moehring, A. et al. Providing normative information increases intentions to accept a COVID-19 vaccine. Nat. Commun. 14, 126 (2023). (PMID: 366240929828376) Buttenheim, A. et al. Effects of ownership text message wording and reminders on receipt of an influenza vaccination: a randomized clinical trial. JAMA Netw. Open 5, e2143388 (2022). (PMID: 351753468855238) Duckworth, A. L. & Milkman, K. L. A guide to megastudies. PNAS Nexus 1, pgac214 (2022). (PMID: 367123339802435) Milkman, K. L. et al. Megastudies improve the impact of applied behavioural science. Nature 600, 478–483 (2021). (PMID: 348804978822539) Patel, M. S. et al. A randomized trial of behavioral nudges delivered through text messages to increase influenza vaccination among patients with an upcoming primary care visit. Am. J. Health Promot. 37, 324–332 (2022). (PMID: 3619598210798571) CDC. Interim clinical considerations for use of COVID-19 vaccines currently approved or authorized in the United States. Centers for Disease Control and Prevention https://www.cdc.gov/vaccines/covid-19/clinical-considerations/interim-considerations-us.html (2023). Mogstad, M., Romano, J. P., Shaikh, A. M. & Wilhelm, D. Inference for ranks with applications to mobility across neighbourhoods and academic achievement across countries. Rev. Econ. Stud. https://doi.org/10.1093/restud/rdad006 (2023). James, W. & Stein, C. Estimation with quadratic loss. In Proc. Fourth Berkeley Symposium on Mathematical Statistics and Probability. Volume 1: Contributions to the Theory of Statistics Vol. 4.1 (ed. Neyman, J.) 361–380 (Univ. California Press, 1961). Khosrowshahi, D. The road to 70 percent: free vaccination rides begin today. Uber https://www.uber.com/newsroom/freevaccinerides/ (2021). The White House. Press briefing by White House COVID-19 Response Team and Public Health Official. The White House https://www.whitehouse.gov/briefing-room/press-briefings/2021/06/08/press-briefing-by-white-house-covid-19-response-team-and-public-health-official/ (2021). DellaVigna, S. & Pope, D. Predicting experimental results: who knows what? J. Polit. Econ. 126, 2410–2456 (2018). Recchia, G., Freeman, A. L. J. & Spiegelhalter, D. How well did experts and laypeople forecast the size of the COVID-19 pandemic? PLoS ONE 16, e0250935 (2021). (PMID: 339510928099086) Kislaya, I. et al. Impact of booster vaccination on COVID-19 outcomes in Portuguese population aged 80 or more years old. Eur. J. Public Health 32, ckac129.666 (2022). Mattiuzzi, C. & Lippi, G. Efficacy of COVID-19 vaccine booster doses in older people. Eur. Geriatr. Med. 13, 275–278 (2022). (PMID: 350679098784276) Pijls, B. G. et al. Demographic risk factors for COVID-19 infection, severity, ICU admission and death: a meta-analysis of 59 studies. BMJ Open 11, e044640 (2021). (PMID: 33431495) Patel, J. A. et al. Poverty, inequality and COVID-19: the forgotten vulnerable. Public Health 183, 110–111 (2020). (PMID: 32502699) Link-Gelles, R. et al. Effectiveness of bivalent mRNA vaccines in preventing symptomatic SARS-CoV-2 infection—increasing community access to testing program, United States, September–November 2022. Morb. Mortal. Wkly Rep. 71, 1526–1530 (2022). WHO. Ten health issues WHO will tackle this year. World Health Organization https://www.who.int/news-room/spotlight/ten-threats-to-global-health-in-2019 (2019). CDC. 14 diseases you almost forgot about (thanks to vaccines). Centers for Disease Control and Prevention https://www.cdc.gov/vaccines/parents/diseases/forgot-14-diseases.html (2022). CDC. Shingles vaccination. Centers for Disease Control and Prevention https://www.cdc.gov/vaccines/vpd/shingles/public/shingrix/index.html (2023). Ferdinands, J. M. et al. Prevention of influenza hospitalization among adults in the United States, 2015–2016: results from the US Hospitalized Adult Influenza Vaccine Effectiveness Network (HAIVEN). J. Infect. Dis. 220, 1265–1275 (2019). (PMID: 30561689) Self, W. H. et al. Comparative effectiveness of Moderna, Pfizer–BioNTech, and Janssen (Johnson & Johnson) vaccines in preventing COVID-19 hospitalizations among adults without immunocompromising conditions—United States, March–August 2021. Morb. Mortal. Wkly Rep. 70, 1337–1343 (2021). Ayoubkhani, D. et al. Trajectory of long COVID symptoms after COVID-19 vaccination: community based cohort study. BMJ 377, e069676 (2022). (PMID: 35584816) Kuodi, P. et al. Association between BNT162b2 vaccination and reported incidence of post-Covid-19 symptoms: cross-sectional study 2020–21, Israel. NPJ Vaccines 7, 101 (2022). (PMID: 360284989411827) Meriggi, N. F. et al. Last-mile delivery increases vaccine uptake in Sierra Leone. Nature 627, 612–619 (2024). (PMID: 3848087710954551) Kaczmarski, M. Uber vs. Lyft: who’s tops in the battle of U.S. rideshare companies. Bloomberg Second Measure https://secondmeasure.com/datapoints/rideshare-industry-overview/ (2023). StataCorp. splitsample. Stata Package v.17.0 https://www.stata.com/manuals/dsplitsample.pdf (2023). Dobson, A. J. & Barnett, A. G. An Introduction to Generalized Linear Models (Chapman and Hall/CRC, 2018). Kass, R. E. & Raftery, A. E. Bayes factors. J. Am. Stat. Assoc. 90, 773–795 (1995). Raftery, A. E. Bayesian model selection in social research. Sociol. Methodol. 25, 111–163 (1995). Wagenmakers, E.-J. A practical solution to the pervasive problems of P values. Psychon. Bull. Rev. 14, 779–804 (2007). (PMID: 18087943) Benjamini, Y. & Hochberg, Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. R. Stat. Soc. Ser. B Methodol. 57, 289–300 (1995). Linos, E., Lasky-Fink, J., Larkin, C., Moore, L. & Kirkman, E. The formality effect. Nat. Hum. Behav. https://doi.org/10.1038/s41562-023-01761-z (2023). Mellers, B. et al. Identifying and cultivating superforecasters as a method of improving probabilistic predictions. Perspect. Psychol. Sci. 10, 267–281 (2015). (PMID: 25987508) Dana, J., Atanasov, P., Tetlock, P. & Mellers, B. Are markets more accurate than polls? The surprising informational value of “just asking”. Judgm. Decis. Mak. 14, 135–147 (2019). |
| المشرفين على المادة: | 0 (COVID-19 Vaccines) 0 (Influenza Vaccines) |
| تواريخ الأحداث: | Date Created: 20240626 Date Completed: 20240703 Latest Revision: 20240730 |
| رمز التحديث: | 20240731 |
| مُعرف محوري في PubMed: | PMC11222156 |
| DOI: | 10.1038/s41586-024-07591-x |
| PMID: | 38926578 |
| قاعدة البيانات: | MEDLINE |
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| DOI: | 10.1038/s41586-024-07591-x |