دورية أكاديمية
Clinical Validation of Carotid-Femoral Pulse Wave Velocity Measurement Using a Multi-Beam Laser Vibrometer: The CARDIS Study.
العنوان: | Clinical Validation of Carotid-Femoral Pulse Wave Velocity Measurement Using a Multi-Beam Laser Vibrometer: The CARDIS Study. |
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المؤلفون: | Badhwar S; Paris Cardiovascular Research Center (PARCC) Institut National de la Santé Et de la Researche Médicale (INSERM), Paris, France (S.B., L.M., F.P., R.M.B., P.B.)., Marais L; Paris Cardiovascular Research Center (PARCC) Institut National de la Santé Et de la Researche Médicale (INSERM), Paris, France (S.B., L.M., F.P., R.M.B., P.B.)., Khettab H; Hôpital européen Georges-Pompidou (HEGP), Assistance publique-Hôpitaux de Paris (APHP), Paris, France (H.K., R.M.B, P.B.)., Poli F; Paris Cardiovascular Research Center (PARCC) Institut National de la Santé Et de la Researche Médicale (INSERM), Paris, France (S.B., L.M., F.P., R.M.B., P.B.)., Li Y; Photonics Research Group, Ghent University-imec, Belgium (Y.L., R.B.).; Center for Nano- and Biophotonics, Ghent University, Belgium (Y.L., R.B.)., Segers P; IBiTech- BioMMedA, Ghent University, Belgium (P.S.)., Aasmul S; Medtronic Bakken Research Center, Maastricht, The Netherlands (S.A., M.d.M.)., de Melis M; Medtronic Bakken Research Center, Maastricht, The Netherlands (S.A., M.d.M.)., Baets R; Photonics Research Group, Ghent University-imec, Belgium (Y.L., R.B.).; Center for Nano- and Biophotonics, Ghent University, Belgium (Y.L., R.B.)., Greenwald S; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom (S.G.)., Bruno RM; Paris Cardiovascular Research Center (PARCC) Institut National de la Santé Et de la Researche Médicale (INSERM), Paris, France (S.B., L.M., F.P., R.M.B., P.B.).; Hôpital européen Georges-Pompidou (HEGP), Assistance publique-Hôpitaux de Paris (APHP), Paris, France (H.K., R.M.B, P.B.).; Université Paris Cité, Faculté de Médecine, France (R.M.B, P.B.)., Boutouyrie P; Paris Cardiovascular Research Center (PARCC) Institut National de la Santé Et de la Researche Médicale (INSERM), Paris, France (S.B., L.M., F.P., R.M.B., P.B.).; Hôpital européen Georges-Pompidou (HEGP), Assistance publique-Hôpitaux de Paris (APHP), Paris, France (H.K., R.M.B, P.B.).; Université Paris Cité, Faculté de Médecine, France (R.M.B, P.B.). |
المصدر: | Hypertension (Dallas, Tex. : 1979) [Hypertension] 2024 Sep; Vol. 81 (9), pp. 1986-1995. Date of Electronic Publication: 2024 Jun 27. |
نوع المنشور: | Clinical Study; Journal Article; Validation Study |
اللغة: | English |
بيانات الدورية: | Publisher: Lippincott, Williams & Wilkins Country of Publication: United States NLM ID: 7906255 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4563 (Electronic) Linking ISSN: 0194911X NLM ISO Abbreviation: Hypertension Subsets: MEDLINE |
أسماء مطبوعة: | Publication: Original Publication: [Dallas, Tex.] : [American Heart Association], [©1979]- |
مواضيع طبية MeSH: | Carotid-Femoral Pulse Wave Velocity*/methods , Vascular Stiffness*/physiology, Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Cardiovascular Diseases/physiopathology ; Cardiovascular Diseases/diagnosis ; Carotid Arteries/physiopathology ; Femoral Artery/physiopathology ; Hypertension/physiopathology ; Hypertension/diagnosis ; Manometry/methods ; Manometry/instrumentation ; Pulse Wave Analysis/methods ; Pulse Wave Analysis/instrumentation ; Reproducibility of Results ; Vibration |
مستخلص: | Background: Carotid-femoral pulse wave velocity (cfPWV) is the gold standard for noninvasive arterial stiffness assessment, an independent predictor of cardiovascular disease, and a potential parameter to guide therapy. However, cfPWV is not routinely measured in clinical practice due to the unavailability of a low-cost, operator-friendly, and independent device. The current study validated a novel laser Doppler vibrometry (LDV)-based measurement of cfPWV against the reference technique. Methods: In 100 (50 men) hypertensive patients, cfPWV was measured using applanation tonometry (Sphygmocor) and the novel LDV device. This device has 2 handpieces with 6 laser beams each that simultaneously measure vibrations from the skin surface at carotid and femoral sites. Pulse wave velocity is calculated using ECG for the identification of cardiac cycles. An ECG-independent method was also devised. Cardiovascular risk score was calculated for patients between 40 and 75 years old using the WHO risk scoring chart. Results: LDV-based cfPWV correlated significantly with tonometry (r=0.86, P <0.0001 ECG-dependent [cfPWV Conclusions: The study demonstrates clinical validity of the LDV device. The LDV provides a simple, noninvasive, operator-independent method to measure cfPWV for assessing arterial stiffness, comparable to the standard existing techniques. Registration: URL: https://clinicaltrials.gov/study/NCT03446430; Unique identifier: NCT03446430. Competing Interests: None. |
فهرسة مساهمة: | Keywords: cardiovascular diseases; carotid-femoral pulse wave velocity; optics and photonics; risk factors; vascular stiffness |
سلسلة جزيئية: | ClinicalTrials.gov NCT03446430 |
تواريخ الأحداث: | Date Created: 20240627 Date Completed: 20240814 Latest Revision: 20240815 |
رمز التحديث: | 20240815 |
مُعرف محوري في PubMed: | PMC11319084 |
DOI: | 10.1161/HYPERTENSIONAHA.124.22729 |
PMID: | 38934112 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1524-4563 |
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DOI: | 10.1161/HYPERTENSIONAHA.124.22729 |