دورية أكاديمية
أعرض في EDS

Clinical and pathophysiologic determinants of catheter ablation outcome in hypertrophic cardiomyopathy with atrial fibrillation.

التفاصيل البيبلوغرافية
العنوان: Clinical and pathophysiologic determinants of catheter ablation outcome in hypertrophic cardiomyopathy with atrial fibrillation.
المؤلفون: Lee JH; Department of Cardiology, Myongji Hospital Hanyang University Medical Center Seoul Republic of Korea., Cho I; Yonsei University Health System Seoul Republic of Korea., Choi SH; Yonsei University Health System Seoul Republic of Korea., Yu HT; Yonsei University Health System Seoul Republic of Korea., Kim TH; Yonsei University Health System Seoul Republic of Korea., Uhm JS; Yonsei University Health System Seoul Republic of Korea., Joung B; Yonsei University Health System Seoul Republic of Korea., Lee MH; Yonsei University Health System Seoul Republic of Korea., Hong GR; Yonsei University Health System Seoul Republic of Korea., Hwang C; Yonsei University Health System Seoul Republic of Korea., Pak HN; Yonsei University Health System Seoul Republic of Korea.
المصدر: Journal of arrhythmia [J Arrhythm] 2024 May 14; Vol. 40 (3), pp. 479-488. Date of Electronic Publication: 2024 May 14 (Print Publication: 2024).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Wiley Country of Publication: Japan NLM ID: 101263026 Publication Model: eCollection Cited Medium: Print ISSN: 1880-4276 (Print) Linking ISSN: 18804276 NLM ISO Abbreviation: J Arrhythm Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: 2018- : Tokyo : Wiley
Original Publication: Tokyo : Japanese Society of Cardiac Pacing and Electrophysiology
مستخلص: Background: Hypertrophic cardiomyopathy (HCM) is frequently associated with atrial fibrillation (AF). We compared clinical, echocardiographic, and electrophysiological parameters between HCM subtypes and those without HCM at AF catheter ablation (AFCA) and analyzed post-AFCA reverse remodeling and AF recurrence based on HCM presence and subtype.
Methods: Among 5161 consecutive patients who underwent de novo AFCA, we included HCM patients and control patients who were age-, gender-, and AF type-matched. Between AF-HCM patients and controls, we compared baseline values for left atrium (LA) wall thickness (LAWT), reverse remodeling at 1-year follow-up, and procedural outcomes over the course of follow-up between two groups.
Results: A total of 122 AF-HCM patients and 318 control patients were included. AF-HCM patients had more frequent heart failure and higher LA diameter, E/Em, and LA pressure (all, p  < .001). However, LAWT did not differ from control group. A year after AFCA, degree of LA reverse remodeling was significantly lower in AF-HCM than in control group (ΔLA dimension, p  = .025). Nonapical HCM (HR 1.71; 95% CI 1.05-2.80), persistent AF (HR 1.46; 95% CI 1.05-2.04), and LA dimension (HR 1.04; 95% CI 1.01-1.06) were independent risk factors for AF recurrence. During 78.0 months of follow-up, nonapical HCM patients showed higher AF recurrence rate than both apical HCM (log-rank p  = .005) and control patients (log-rank p  = .002).
Conclusions: The presence of HCM, particularly nonapical HCM, displayed increased LA hemodynamic loading with diastolic dysfunction and had poorer rhythm outcomes after AFCA compared to both apical HCM and control group.
Competing Interests: The authors declare no conflict of interest.
(© 2024 The Authors. Journal of Arrhythmia published by John Wiley & Sons Australia, Ltd on behalf of Japanese Heart Rhythm Society.)
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فهرسة مساهمة: Keywords: atrial fibrillation; atrial wall thickness; catheter ablation; hypertrophic cardiomyopathy
تواريخ الأحداث: Date Created: 20240628 Latest Revision: 20240629
رمز التحديث: 20240629
مُعرف محوري في PubMed: PMC11199821
DOI: 10.1002/joa3.13061
PMID: 38939784
قاعدة البيانات: MEDLINE
الوصف
تدمد:1880-4276
DOI:10.1002/joa3.13061