دورية أكاديمية
A Possible Neural Basis for Attentional Capture of Faces Revealed by Functional Magnetic Resonance Imaging and Causal Pharmacological Inactivation in Macaques.
| العنوان: | A Possible Neural Basis for Attentional Capture of Faces Revealed by Functional Magnetic Resonance Imaging and Causal Pharmacological Inactivation in Macaques. |
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| المؤلفون: | Liu N; University of Chinese Academy of Sciences, Beijing, China., Avidan G; Ben-Gurion University of the Negev, Beersheba, Israel., Turchi JN; NIMH, NIH, Bethesda, MD., Hadj-Bouziane F; Lyon Neuroscience Research Center.; University UCBL Lyon 1., Behrmann M; University of Pittsburgh.; Carnegie Mellon University, Pittsburgh, PA. |
| المصدر: | Journal of cognitive neuroscience [J Cogn Neurosci] 2024 Jun 26, pp. 1-19. Date of Electronic Publication: 2024 Jun 26. |
| Publication Model: | Ahead of Print |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Published by the MIT Press with the Cognitive Neuroscience Institute Country of Publication: United States NLM ID: 8910747 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-8898 (Electronic) Linking ISSN: 0898929X NLM ISO Abbreviation: J Cogn Neurosci Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Cambridge, Mass. : Published by the MIT Press with the Cognitive Neuroscience Institute, c1989- |
| مستخلص: | In primates, the presence of a face in a visual scene captures attention and rapidly directs the observer's gaze to the face, even when the face is not relevant to the task at hand. Here, we explored a neural circuit that might potentially play a causal role in this powerful behavior. In our previous research, two monkeys received microinfusions of muscimol, a GABAA-receptor agonist, or saline (as a control condition) in separate sessions into individual or pairs of four inferotemporal face patches (middle and anterior lateral and fundal), as identified by a preceding face localizer experiment. Then, using fMRI, we measured the impact of each inactivation condition on responses in the other face patches relative to the control condition. In this study, we used the same method and measured the impact of each inactivation condition on responses in the FEF and the lateral intraparietal area, two regions associated with attentional processing, while face and nonface object stimuli were viewed. Our results revealed potential relationships between inferotemporal face patches and these two attention-related regions: The inactivation of the middle lateral and anterior fundal face patches had a pronounced impact on FEF, whereas the inactivation of the middle and anterior lateral face patches might have a noticeable influence on lateral intraparietal area. Together, these initial exploratory findings document a circuit that potentially underlies the attentional capture of faces. Confirmation of the role of this circuit remains to be accomplished in the context of paradigm explicitly testing the attentional capture of faces. (© 2024 Massachusetts Institute of Technology.) |
| معلومات مُعتمدة: | 2021ZD0200200 STI2030-Major Projects; 32071094 National Natural Science Foundation of China; ZIAMH002918 National Institute of Mental Health Intramural Research Program; R01EY027018 United States EY NEI NIH HHS; EY08098 United States EY NEI NIH HHS; United States NH NIH HHS; The Research to Prevent Blindness Inc., NY; Eye & Ear Foundation of Pittsburgh |
| تواريخ الأحداث: | Date Created: 20240628 Latest Revision: 20240628 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1162/jocn_a_02211 |
| PMID: | 38940721 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1530-8898 |
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| DOI: | 10.1162/jocn_a_02211 |