دورية أكاديمية
Trend change analysis of postural balance in Parkinson's disease discriminates between medication state.
العنوان: | Trend change analysis of postural balance in Parkinson's disease discriminates between medication state. |
---|---|
المؤلفون: | Wodarski P; Faculty of Biomedical Engineering, Department of Biomechatronics, Silesian University of Technology, Gliwice, Poland., Jurkojć J; Faculty of Biomedical Engineering, Department of Biomechatronics, Silesian University of Technology, Gliwice, Poland., Chmura M; Faculty of Biomedical Engineering, Department of Biomechatronics, Silesian University of Technology, Gliwice, Poland., Warmerdam E; Division of Surgery, Saarland University, 66421, Homburg, Germany., Romijnders R; Department of Neurology, Kiel University, 24105, Kiel, Germany., Hobert MA; Department of Neurology, Kiel University, 24105, Kiel, Germany., Maetzler W; Department of Neurology, Kiel University, 24105, Kiel, Germany., Cygoń K; Skyfi Sp. z o.o, Gliwice, Poland., Hansen C; Department of Neurology, Kiel University, 24105, Kiel, Germany. C.Hansen@neurologie.uni-kiel.de. |
المصدر: | Journal of neuroengineering and rehabilitation [J Neuroeng Rehabil] 2024 Jun 28; Vol. 21 (1), pp. 112. Date of Electronic Publication: 2024 Jun 28. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: BioMed Central Country of Publication: England NLM ID: 101232233 Publication Model: Electronic Cited Medium: Internet ISSN: 1743-0003 (Electronic) Linking ISSN: 17430003 NLM ISO Abbreviation: J Neuroeng Rehabil Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: [London] : BioMed Central, 2004- |
مواضيع طبية MeSH: | Parkinson Disease*/physiopathology , Parkinson Disease*/diagnosis , Parkinson Disease*/drug therapy , Postural Balance*/physiology, Humans ; Male ; Female ; Aged ; Middle Aged ; Adult ; Antiparkinson Agents/therapeutic use ; Young Adult |
مستخلص: | Background: Maintaining static balance is relevant and common in everyday life and it depends on a correct intersegmental coordination. A change or reduction in postural capacity has been linked to increased risk of falls. People with Parkinson's disease (pwPD) experience motor symptoms affecting the maintenance of a stable posture. The aim of the study is to understand the intersegmental changes in postural sway and to apply a trend change analysis to uncover different movement strategies between pwPD and healthy adults. Methods: In total, 61 healthy participants, 40 young (YO), 21 old participants (OP), and 29 pwPD (13 during medication off, PDoff; 23 during medication on, PDon) were included. Participants stood quietly for 10 s as part of the Short Physical Performance Battery. Inertial measurement units (IMU) at the head, sternum, and lumbar region were used to extract postural parameters and a trend change analysis (TCA) was performed to compare between groups. Objective: This study aims to explore the potential application of TCA for the assessment of postural stability using IMUs, and secondly, to employ this analysis within the context of neurological diseases, specifically Parkinson's disease. Results: Comparison of sensors locations revealed significant differences between head, sternum and pelvis for almost all parameters and cohorts. When comparing PDon and PDoff, the TCA revealed differences that were not seen by any other parameter. Conclusions: While all parameters could differentiate between sensor locations, no group differences could be uncovered except for the TCA that allowed to distinguish between the PD on/off. The potential of the TCA to assess disease progression, response to treatment or even the prodromal PD phase should be explored in future studies. Trial Registration: The research procedure was approved by the ethical committee of the Medical Faculty of Kiel University (D438/18). The study is registered in the German Clinical Trials Register (DRKS00022998). (© 2024. The Author(s).) |
References: | J Neurophysiol. 2019 Feb 1;121(2):672-689. (PMID: 30461364) J Neurol Neurosurg Psychiatry. 1987 Jan;50(1):66-70. (PMID: 3819757) J Sci Med Sport. 2009 Jan;12(1):60-6. (PMID: 18054520) J Biomech. 2020 Nov 9;112:110045. (PMID: 33011672) Front Aging Neurosci. 2022 Dec 22;14:1070093. (PMID: 36620765) Hum Factors. 2019 Aug;61(5):702-711. (PMID: 30130130) BMC Neurol. 2018 Aug 16;18(1):114. (PMID: 30115021) Front Neurol. 2022 Mar 29;13:857406. (PMID: 35422747) Brain Sci. 2019 Sep 18;9(9):. (PMID: 31540441) Ann Phys Rehabil Med. 2012 Dec;55(9-10):590-600. (PMID: 23165246) Brain Sci. 2023 Aug 07;13(8):. (PMID: 37626529) Gait Posture. 2012 Apr;35(4):573-8. (PMID: 22277368) Exp Brain Res. 1986;64(1):59-69. (PMID: 3490396) J Neurophysiol. 2008 Dec;100(6):3197-208. (PMID: 18829852) J Hum Kinet. 2023 Jul 15;87:51-62. (PMID: 37559767) J Neuroeng Rehabil. 2012 Aug 22;9:59. (PMID: 22913719) Neuroimage. 2003 Jul;19(3):764-76. (PMID: 12880805) Mov Disord. 2015 Oct;30(12):1591-601. (PMID: 26474316) Exp Neurol. 2005 Jun;193(2):504-21. (PMID: 15869953) J Physiol. 1992 Aug;454:533-47. (PMID: 1474502) Can J Neurol Sci. 2008 Mar;35(1):65-8. (PMID: 18380279) Mov Disord. 2011 Mar;26(4):637-43. (PMID: 21312283) J Am Geriatr Soc. 2005 Apr;53(4):695-9. (PMID: 15817019) Int J Environ Res Public Health. 2021 Mar 31;18(7):. (PMID: 33807432) CNS Drugs. 2013 Feb;27(2):97-112. (PMID: 23076544) Gait Posture. 2012 Jul;36(3):471-6. (PMID: 22750016) Sensors (Basel). 2021 Aug 30;21(17):. (PMID: 34502726) Front Neurosci. 2018 Jan 19;12:3. (PMID: 29403348) J Mov Disord. 2017 Jan;10(1):1-17. (PMID: 28122432) Neurosci Lett. 2006 Jun 19;401(1-2):92-6. (PMID: 16574321) Gait Posture. 2005 Nov;22(3):240-9. (PMID: 16278966) Sensors (Basel). 2018 Feb 28;18(3):. (PMID: 29495600) Parkinsonism Relat Disord. 2011 Aug;17(7):557-62. (PMID: 21641263) J Neuroeng Rehabil. 2023 Aug 2;20(1):99. (PMID: 37528430) Neurol Res. 2018 Jun;40(6):491-498. (PMID: 29869975) Exp Brain Res. 1990;82(1):97-106. (PMID: 2257917) Neuroscience. 2009 Jul 7;161(3):904-14. (PMID: 19362125) Eur J Neurol. 2020 Jan;27(1):27-42. (PMID: 31631455) Acta Otolaryngol. 2010 Dec;130(12):1358-63. (PMID: 20632903) Dtsch Med Wochenschr. 2005 Apr 15;130(15):958-60; quiz 965-8. (PMID: 15812721) Neuroscience. 2012 Jun 28;213:62-71. (PMID: 22521818) |
فهرسة مساهمة: | Keywords: Balance; Body balance; Neurology; Parkinson Disease; Postural Stability; Trend Change Index; Wearable sensors |
المشرفين على المادة: | 0 (Antiparkinson Agents) |
تواريخ الأحداث: | Date Created: 20240629 Date Completed: 20240629 Latest Revision: 20240701 |
رمز التحديث: | 20240701 |
مُعرف محوري في PubMed: | PMC11212256 |
DOI: | 10.1186/s12984-024-01411-z |
PMID: | 38943208 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1743-0003 |
---|---|
DOI: | 10.1186/s12984-024-01411-z |