دورية أكاديمية

Effect of Non-ablative Medical Therapy on Progression of Hearing Loss in Menière's Disease: A Systematic Review and meta-Analysis.

التفاصيل البيبلوغرافية
العنوان: Effect of Non-ablative Medical Therapy on Progression of Hearing Loss in Menière's Disease: A Systematic Review and meta-Analysis.
المؤلفون: Thompson-Harvey A; Department of Otolaryngology-Head & Neck Surgery, University of Virginia, Charlottesville, Virginia., Pyle M; Department of Otolaryngology-Head & Neck Surgery, University of Miami Miller School of Medicine, Miami, Florida., Harvey E; Department of Otolaryngology & Communication Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin., Harris MS; Department of Otolaryngology & Communication Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin.
المصدر: Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology [Otol Neurotol] 2024 Sep 01; Vol. 45 (8), pp. 833-839. Date of Electronic Publication: 2024 Jul 03.
نوع المنشور: Journal Article; Systematic Review; Meta-Analysis
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 100961504 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-4505 (Electronic) Linking ISSN: 15317129 NLM ISO Abbreviation: Otol Neurotol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Hagerstown, MD : Lippincott Williams & Wilkins, c2001-
مواضيع طبية MeSH: Meniere Disease*/therapy , Meniere Disease*/surgery , Hearing Loss*/etiology , Disease Progression*, Humans ; Audiometry, Pure-Tone
مستخلص: Objective: To systematically review how audiometric data change over time in patients with Menière's disease (MD) undergoing non-ablative medical therapy.
Databases Reviewed: Medline (via PubMed), Scopus, Web of Science, Cumulated Index to Nursing and Allied Health Literature (CINAHL), Google Scholar.
Methods: A systematic review and meta-analysis of the literature was performed. Adult patients undergoing non-ablative medical therapy and reported duration of disease or follow-up were included and pooled estimates of pure-tone average (PTA) were tabulated. Studies were excluded if they did not use established MD, did not have pure-tone average (PTA) audiometric data, underwent ear surgery or ablative therapies, and were systematic reviews or case reports.
Results: Out of 198 articles meeting full eligibility, 13 studies, involving 950 patients with MD, were included in the review and further analyzed. No effect on progression of PTA from initial diagnosis was seen between the different medical therapies within 2 years of non-ablative medical treatment. There was a significant worsening of PTA after 2 year, regardless of treatment used. High levels of heterogeneity among studies were noted up to 6 months from diagnosis ( I2 = 79%), likely reflecting differences in patient characteristics, treatment regimens, and study design. Overall, the risk of bias was low for the majority of included studies.
Conclusions: Patients diagnosed with MD who are undergoing non-ablative medical therapy should be counseled on the likelihood of worsening of hearing loss over the course of the disease despite elected treatment.
Competing Interests: The authors disclose no conflicts of interest.
(Copyright © 2024, Otology & Neurotology, Inc.)
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تواريخ الأحداث: Date Created: 20240703 Date Completed: 20240814 Latest Revision: 20240815
رمز التحديث: 20240815
DOI: 10.1097/MAO.0000000000004251
PMID: 38956802
قاعدة البيانات: MEDLINE
الوصف
تدمد:1537-4505
DOI:10.1097/MAO.0000000000004251