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Phytochemical-mediated regulation of aflatoxigenic fungi contamination in a shifting climate and environment.

التفاصيل البيبلوغرافية
العنوان: Phytochemical-mediated regulation of aflatoxigenic fungi contamination in a shifting climate and environment.
المؤلفون: Zaman S; Department of Botany, University of Malakand, Chakdara, KPK, Pakistan. shahzaman@uom.edu.pk., Khan N; Department of Botany, University of Malakand, Chakdara, KPK, Pakistan., Zahoor M; Department of Biochemistry, University of Malakand, Chakdara, KPK, Pakistan., Ullah R; Departement of Pharmacognosy, College of Pharmacy King Saud University, Riyadh, Saudi Arabia., Bari A; Departement of Pharmaceutical Chemistry, College of Pharmacy King Saud University, Riyadh, Saudi Arabia., Sohail; College of Bioscience and Biotechnology, Yangzhou University, Yangzhou, 225009, Jiangsu, China.
المصدر: Environmental geochemistry and health [Environ Geochem Health] 2024 Jul 03; Vol. 46 (8), pp. 272. Date of Electronic Publication: 2024 Jul 03.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Kluwer Academic Publishers Country of Publication: Netherlands NLM ID: 8903118 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-2983 (Electronic) Linking ISSN: 02694042 NLM ISO Abbreviation: Environ Geochem Health Subsets: MEDLINE
أسماء مطبوعة: Publication: 1999- : Dordrecht : Kluwer Academic Publishers
Original Publication: Kew, Surrey : Science and Technology Letters, 1985-
مواضيع طبية MeSH: Aflatoxins*/analysis , Phytochemicals*/pharmacology , Phytochemicals*/analysis, Pakistan ; Plants, Medicinal/chemistry ; Plants, Medicinal/microbiology ; Climate
مستخلص: Mycotoxin contamination poses a significant problem in developing countries, particularly in northern Pakistan's fluctuating climate. This study aimed to assess aflatoxin contamination in medicinal and condiment plants in Upper Dir (dry-temperate) and Upper Swat (moist-temperate) districts. Plant samples were collected and screened for mycotoxins (Aflatoxin-B1 and Aflatoxin-B-2). Results showed high levels of AFB-1 (11,505.42 ± 188.82) as compared to AFB-2 (846 ± 241.56). The maximum contamination of AFB-1 in Coriandrum sativum (1154.5 ± 13.43 ng to 3328 ± 9.9 ng) followed by F. vulgare (883 ± 9.89 ng to 2483 ± 8.4 ng), T. ammi (815 ± 11.31 ng to 2316 ± 7.1 ng), and C. longa (935.5 ± 2.12 ng to 2009 ± 4.2 ng) while the minimum was reported in C. cyminum (671 ± 9.91 ng to 1995 ± 5.7 ng). Antifungal tests indicated potential resistance in certain plant species (C. cyminum) while A. flavus as the most toxins contributing species due to high resistance below 80% (54.2 ± 0.55 to 79.5 ± 2.02). HPLC analysis revealed hydroxyl benzoic acid (5136 amu) as the dominant average phytochemical followed by phloroglucinol (4144.31 amu) with individual contribution of 8542.08 amu and 12,181.5 amu from C. cyaminum. The comparison of average phytochemicals revealed the maximum concentration in C. cyminum (2885.95) followed by C. longa (1892.73). The findings revealed a statistically significant and robust negative correlation (y = - 2.7239 ×  + 5141.9; r = - 0.8136; p < 0.05) between average mycotoxins and phytochemical concentrations. Temperature positively correlated with aflatoxin levels (p < 0.01), while humidity had a weaker correlation. Elevation showed a negative correlation (p < 0.05), while geographical factors (latitude and longitude) had mixed correlations (p < 0.05). Specific regions exhibited increasing aflatoxin trends due to climatic and geographic factors.
(© 2024. The Author(s), under exclusive licence to Springer Nature B.V.)
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فهرسة مساهمة: Keywords: Fluctuating climatic-geographical factors; HPLC-based phytochemicals; Mycotoxin contamination trends; Northern-Pakistan
المشرفين على المادة: 0 (Aflatoxins)
0 (Phytochemicals)
تواريخ الأحداث: Date Created: 20240703 Date Completed: 20240703 Latest Revision: 20240703
رمز التحديث: 20240703
DOI: 10.1007/s10653-024-02045-9
PMID: 38958785
قاعدة البيانات: MEDLINE
الوصف
تدمد:1573-2983
DOI:10.1007/s10653-024-02045-9