دورية أكاديمية
أعرض في EDS

Effects of Balanced Versus Saline-based Solutions on Acute Kidney Injury in Off-pump Coronary Artery Bypass Surgery: A Randomized Controlled Trial.

التفاصيل البيبلوغرافية
العنوان: Effects of Balanced Versus Saline-based Solutions on Acute Kidney Injury in Off-pump Coronary Artery Bypass Surgery: A Randomized Controlled Trial.
المؤلفون: Nam JS; Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Kim WJ; Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. Electronic address: wookjong.kim@amc.seoul.kr., Seo WW; Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Lee SW; Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Joung KW; Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Chin JH; Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Choi DK; Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Choi IC; Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
المصدر: Journal of cardiothoracic and vascular anesthesia [J Cardiothorac Vasc Anesth] 2024 Sep; Vol. 38 (9), pp. 1923-1931. Date of Electronic Publication: 2024 Jun 04.
نوع المنشور: Journal Article; Randomized Controlled Trial; Comparative Study
اللغة: English
بيانات الدورية: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 9110208 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8422 (Electronic) Linking ISSN: 10530770 NLM ISO Abbreviation: J Cardiothorac Vasc Anesth Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Philadelphia, PA : W.B. Saunders, c1991-
مواضيع طبية MeSH: Acute Kidney Injury*/prevention & control , Acute Kidney Injury*/etiology , Acute Kidney Injury*/epidemiology , Coronary Artery Bypass, Off-Pump*/methods , Coronary Artery Bypass, Off-Pump*/adverse effects , Saline Solution*/administration & dosage , Postoperative Complications*/prevention & control , Postoperative Complications*/epidemiology , Postoperative Complications*/etiology, Humans ; Male ; Female ; Middle Aged ; Aged ; Fluid Therapy/methods
مستخلص: Objectives: To determine whether balanced solutions can reduce the incidence of acute kidney injury after off-pump coronary artery bypass surgery compared with saline.
Design: Randomized controlled trial.
Setting: Single tertiary care center.
Participants: Patients who underwent off-pump coronary artery bypass surgery between June 2014 and July 2020.
Interventions: Balanced solution-based chloride-restrictive intravenous fluid strategy.
Measurements and Main Results: The primary outcome was acute kidney injury within 7 postoperative days, as defined by the 2012 Kidney Disease: Improving Global Outcomes Clinical Practice Guideline. The incidence of acute kidney injury was 4.4% (8/180) in the balanced group and 7.3% (13/178) in the saline group. The difference was not statistically significant (risk difference, -2.86%; 95% confidence interval [CI], -7.72% to 2.01%; risk ratio, 0.61, 95% CI, 0.26 to 1.43; p = 0.35). Compared with the balanced group, the saline group had higher levels of intraoperative serum chloride and lower base excess, which resulted in a lower pH.
Conclusions: In patients undergoing off-pump bypass surgery with a normal estimated glomerular filtration rate, the intraoperative balanced solution-based chloride-restrictive intravenous fluid administration strategy did not decrease the rate of postoperative acute kidney injury compared with the saline-based chloride-liberal intravenous fluid administration strategy.
Competing Interests: Declaration of competing interest None.
(Copyright © 2024 Elsevier Inc. All rights reserved.)
فهرسة مساهمة: Keywords: acute kidney injury; balanced solution; coronary artery bypass; fluid therapy; off-pump; sodium chloride
المشرفين على المادة: 0 (Saline Solution)
تواريخ الأحداث: Date Created: 20240703 Date Completed: 20240822 Latest Revision: 20240822
رمز التحديث: 20240823
DOI: 10.1053/j.jvca.2024.06.001
PMID: 38960803
قاعدة البيانات: MEDLINE
الوصف
تدمد:1532-8422
DOI:10.1053/j.jvca.2024.06.001