دورية أكاديمية
Relationship between histopathological findings of patients with dermatochalasis and vitamin D deficiency.
العنوان: | Relationship between histopathological findings of patients with dermatochalasis and vitamin D deficiency. |
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المؤلفون: | Aydemir E; Department of Ophthalmology, Antalya City Hospital, Antalya, Turkey., Malkoç Şen E; Department of Ophthalmology, Ankara Etlik City Hospital, Ankara, Turkey., Aksoy Aydemir G; Department of Ophthalmology, Antalya City Hospital, Antalya, Turkey. gzdaksoy@hotmail.com., Bayat AH; Department of Ophthalmology, Istanbul Medipol University, Istanbul, Turkey., Karnaz A; Department of Ophthalmology, Nizip State Hospital, Gaziantep, Turkey., Aydın Türk B; Department of Pathology, Adıyaman University Education and Research Hospital, Adıyaman, Turkey. |
المصدر: | International ophthalmology [Int Ophthalmol] 2024 Jul 03; Vol. 44 (1), pp. 309. Date of Electronic Publication: 2024 Jul 03. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Kluwer Country of Publication: Netherlands NLM ID: 7904294 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-2630 (Electronic) Linking ISSN: 01655701 NLM ISO Abbreviation: Int Ophthalmol Subsets: MEDLINE |
أسماء مطبوعة: | Publication: Dordrecht : Kluwer Original Publication: The Hague, Junk. |
مواضيع طبية MeSH: | Blepharoplasty*/methods , Vitamin D Deficiency*/complications , Vitamin D Deficiency*/diagnosis, Humans ; Male ; Prospective Studies ; Female ; Middle Aged ; Aged ; Eyelid Diseases/pathology ; Eyelid Diseases/diagnosis ; Adult ; Eyelids/pathology ; Vitamin D/blood |
مستخلص: | Purpose: To compare the histopathological findings of patients who had been diagnosed with dermatochalasis (DC) and had undergone upper eyelid blepharoplasty (ULB) as well as those of controls (C-Group) according to their serum vitamin D (SVD) levels. Methods: The prospective study included 136 upper eyelid skin from 68 patients who underwent surgery for DC and 53 upper eyelid skin from 53 patients who underwent levator surgery with ULB. The DC Group was then divided into 3 subgroups according to the marginal reflex distance (MRD4). The lymphatic vessel (LV) count and diameter of the largest LV (DLLV) were recorded, the stromal collagen bed (SCB) was observed, and its depth was measured, the interfibrillar edema was examined, and the elastic fiber and macrophage counts and recorded, respectively, and then all of these were evaluated. The SVD levels were compared between the DC patients and the C-Group. Results: In comparison to the C-Group, significant changes were seen in the dilated LV, DLLV, SCB depth, interfibrillar edema, elastic fiber density, and macrophage count in the DC sub-Groups (P < 0.001 for all). While no difference was found between DC sub-Group 1 (MRD4 > 4 mm) and the C-Group (P > 0.05), a significant difference was found between DC sub-Group 2 (MRD4 2-4 mm) and DC sub-Group 3 (MRD4 < 2 mm) for all of the parameters (P < 0.05). A statistically significant difference was also found in the SVD levels between the DC sub-Group 1 and DC sub-Groups 2-3 (P < 0.017, P < 0.001 respectively). Conclusion: According to the results of this study, SVD level was significantly lower in DC group. Moreover, an increased LV count and diameter, decreased elastic fiber count, collagen fiber and stromal edema irregularity, and increased macrophage count were found to be associated with the SVD level. (© 2024. The Author(s), under exclusive licence to Springer Nature B.V.) |
References: | Karnaz A, Katircioglu YA, Ozdemir ES et al (2018) The Histopathological fndings of patients who underwent blepharoplasty due to dermatochalasis. Semin Ophthalmol 33:407–411. (PMID: 10.1080/08820538.2017.128297028165850) Bhattacharjee K, Misra DK, Deori N (2017) Updates on upper eyelid blepharoplasty. Indian J Ophthalmol 65:551–558. (PMID: 10.4103/ijo.IJO_540_17287248105549405) Gilliland GD. Dermatochalasis. http://emedicine.medscape.com/ article/1212294-overview. Stingl G, Katz SI, Clement L (1978) Immunologic function of Ia-bearing Langerhans cells. J Immunol 121(5):2005–2013. (PMID: 10.4049/jimmunol.121.5.200581860) Silberberg-Sinakin I, Thorbecke GJ (1980) Contact hypersensitivity and Langerhans cells. J Invest Dermatol 75(1):61–67. (PMID: 10.1111/1523-1747.ep125211447391610) Choi K, Sauder DN (1986) The role of Langerhans cells and keratinocytes in epidermal immunity. J Leukocyte Biol 39(3):343–358. (PMID: 10.1002/jlb.39.3.3432418143) Putterman AM, Fagien S, Burroughs JR (2008) The upper periorbita. In: Fagien S (ed) Putterman’s cosmetic oculoplastic surgery, 4th edn. Saunders, Chicago, pp 67–144. Nebbioso M, Buomprisco G, Pascarella A, Pescosolida N (2017) Modulatory effects of 1,25-dihydroxyvitamin D3 on eye disorders: critical review. Crit Rev Food Sci Nutr 57(3):559–565. (PMID: 10.1080/10408398.2014.89350426054653) Nikooyeh B, Neyestani TR (2016) Oxidative stress, type 2 diabetes and vitamin D: past, present and future. Diabetes Metab Res Rev 32(3):260–267. (PMID: 10.1002/dmrr.271826409185) Alsalem JA, Patel D, Susarla R et al (2014) Characterization of vitamin D production by human ocular barrier cells. Invest Ophthalmol Vis Sci 55(4):2140–2147. (PMID: 10.1167/iovs.13-1301924576880) Johnson JA, Grande JP, Roche PC, Campbell RJ, Kumar R (1995) Immunolocalization of the calcitriol receptor, calbindin-D28k and the plasma membrane calcium pump in the human eye. Curr Eye Res 14(2):101–108. (PMID: 10.3109/027136895089999217539352) Aydemir E, Ilhan C, AksoyAydemir G, Bayat AH, Bolu S, Asik A (2022) Evaluation of retinal structure in pediatric subjects with vitamin D deficiency. Am J Ophthalmol 233:30–37. (PMID: 10.1016/j.ajo.2021.06.03134283984) Kim HT, Kim JM, Kim JH et al (2016) The relationship between vitamin D and glaucoma: a Kangbuk Samsung health study. Korean J Ophthalmol 30(6):426–433. (PMID: 10.3341/kjo.2016.30.6.426279803615156616) Garcia Layana A, Minnella AM, Garhoefer G et al (2017) Vitamin D and age-related macular degeneration. Nutrients 9(10):1120. (PMID: 10.3390/nu91011205691736) Bener A, Eliaçık M, Cincik H, Ozturk M, DeFronzo RA, Abdul-Ghani M (2018) The impact of vitamin D deficiency on retinopathy and hearing loss among type 2 diabetic patients. BioMed Res Int 2018:2714590. (PMID: 10.1155/2018/2714590301123726077590) Burton JM, Eliasziw M, Trufyn J, Tung C, Carter G, Costello F (2017) A prospective cohort study of vitamin D in optic neuritis recovery. Mult Scler 23(1):82–93. (PMID: 10.1177/135245851664231527037181) Seyyar SA, Tokuc EO (2023) Evaluation of 25-Hydroxyvitamin D levels in patients with dermatochalasis. Int Ophthalmol 43(3):749–756. (PMID: 10.1007/s10792-022-02474-436036327) Putterman AM (2021) The margin reflex distance four (MRD-4) to determine the medical necessity of upper blepharoplasty and brow-lifting. Ophthalmic Plast Reconstr Surg 37(4):391. https://doi.org/10.1097/IOP.0000000000001922. (PMID: 10.1097/IOP.000000000000192234229335) Ilhan C, Aydemir GA, Aydemir E (2022) Changes in intraocular pressure and ocular biometry after blepharoplasty. Aesthet Plast Surg 46(5):2295–2300. (PMID: 10.1007/s00266-021-02756-9) Holick MF, Binkley NC, Bischof-Ferrari HA et al (2011) Evaluation, treatment, and prevention of vitamin D defciency: an endocrine society clinical practice guideline. J Clin Endocrinol Metab 96:1911–1930. (PMID: 10.1210/jc.2011-038521646368) Agliano M, Lorenzoni P, Volpi N et al (2008) Lymphatic vessels in human eyelids. An immunohistological study in dermatochalasis and chalazion. Lymphology 41(1):29–39. (PMID: 18581956) Nagi KS, Carlson JA, Wladis EJ (2011) Histologic assessment of dermatochalasis: elastolysis and lymphostasis are fundamental and interrelated findings. Ophthalmology 118(6):1205–1210. (PMID: 10.1016/j.ophtha.2010.10.01321211847) Dozsa A, Karolyi ZS, Degrell P (2005) Bilateral blepharochalasis. J Eur Acad Dermatol Venereol 19:725–728. (PMID: 10.1111/j.1468-3083.2005.01252.x16268879) Daroczy J (1995) Pathology of lymphedema. Clin Dermatol 13:433–444. (PMID: 10.1016/0738-081X(95)00086-U8665454) Ryan TJ (1989) Structure and function of lymphatics. J Invest Dermatol 93:18–24. (PMID: 10.1038/jid.1989.4) Kaiserling E (2006) Morphologic changes in lymphedema and tumors. In: Földi M, Földi E (eds) Földi’s textbook of lymphology for physicians and lymphedema therapists, 2nd edn. Elsevier, Munich, pp 322–390. Bilak Ş, Yılmaz S, Bilgin B (2021) Comparison of vitamin D levels between patients with pterygium and healthy subjects. Int Ophthalmol 41:3057–3064. (PMID: 10.1007/s10792-021-01868-033881669) AksoyAydemir G, Ilhan C, Pehlıvanoglu B, Aydemir E, Kiziltoprak H, Bolu S (2022) Conjunctival histopathological changes in children with vitamin D deficiency. Eye Contact Lens 48(7):289–294. (PMID: 10.1097/ICL.0000000000000903) Mantell DJ, Owens PE, Bundred NJ, Mawer EB, Canfeld AE (2000) 1alpha,25-dihydroxyvitamin D(3) inhibits angiogenesis in vitro and in vivo. Circ Res 87(3):214–220. (PMID: 10.1161/01.RES.87.3.21410926872) Zittermann A, Koerfer R (2008) Protective and toxic effects of vitamin D on vascular calcification: clinical implications. Mol Asp Med 29(6):423–432. (PMID: 10.1016/j.mam.2008.04.002) Mutlu U, Ikram MA, Hofman A et al (2016) Vitamin D and retinal microvascular damage. Medicine (Baltimore) 95(49):e5477. (PMID: 10.1097/MD.000000000000547727930528) Yang L, Ma J, Zhang X, Fan Y, Wang L (2012) Protective role of the vitamin D receptor. Cell Immunol 279(2):160–166. (PMID: 10.1016/j.cellimm.2012.10.00223246677) Wang Y, Chiang YH, Su TP et al (2000) Vitamin D3 attenuates cortical infarction induced by middle cerebral arterial ligation in rats. Neuropharmacology 39(5):873–880. (PMID: 10.1016/S0028-3908(99)00255-510699453) Annweiler C, Beauchet O, Bartha R, Graffe A, Milea D, Montero-Odasso M (2013) Association between serum 25-hydroxyvitamin D concentration and optic chiasm volume. J Am Geriatr Soc 61(6):1026–1028. (PMID: 10.1111/jgs.1224923772728) Alia E, Kerr PE (2021) Vitamin D: skin, sunshine, and beyond. Clin Dermatol 39:840–846. (PMID: 10.1016/j.clindermatol.2021.05.02534785011) Holick MF (2007) Vitamin D deficiency. N Engl J Med 357:266–281. (PMID: 10.1056/NEJMra07055317634462) Annweiler C, Souberbielle JC, Schott AM, Decker L, Berrut G, Beauchet O (2011) Vitamin D in the elderly: 5 points to remember. Geriatr Psychol Neuropsychiatr Vieil 9(3):259–267. (PMID: 21896429) Tohari AM, Almarhoun M, Alhasani RH et al (2020) Protection by vitamin D against high-glucose-induced damage in retinal pigment epithelial cells. Exp Cell Res 392(1):112023. (PMID: 10.1016/j.yexcr.2020.11202332325079) Shen CL, Samathanam C, Graham S, Dagda RY, Chyu MC, Dunn DM (2012) Green tea polyphenols and 1-alpha-OH-vitamin D (3) attenuate chronic inflammation-induced myocardial fibrosis in female rats. J Med Food 15(3):269–277. (PMID: 10.1089/jmf.2011.016322181074) Stofels K, Overbergh L, Bouillon R, Mathieu C (2007) Immune regulation of 1alpha-hydroxylase in murine peritoneal macrophages: unravelling the IFNgamma pathway. J Steroid Biochem Mol Biol 103:567–571. (PMID: 10.1016/j.jsbmb.2006.12.091) Rajakumar K, Holick MF, Jeong K et al (2011) Impact of season and diet on vitamin D status of African American and Caucasian children. Clin Pediatr (Phila) 50(6):493–502. (PMID: 10.1177/000992281039733421565884) Johnson DD, Wagner CL, Hulsey TC, McNeil RB, Ebeling M, Hollis BW (2011) Vitamin D deficiency and insufficiency is common during pregnancy. Am J Perinatol 28(1):7–12. (PMID: 10.1055/s-0030-126250520640974) |
فهرسة مساهمة: | Keywords: Collagen; Dermatochalasis; Elastic fiber; Histopathology; Serum vitamin D; Vitamin D deficiency |
المشرفين على المادة: | 1406-16-2 (Vitamin D) |
تواريخ الأحداث: | Date Created: 20240703 Date Completed: 20240703 Latest Revision: 20240703 |
رمز التحديث: | 20240704 |
DOI: | 10.1007/s10792-024-03209-3 |
PMID: | 38960909 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1573-2630 |
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DOI: | 10.1007/s10792-024-03209-3 |