دورية أكاديمية
أعرض في EDS

Relationship between histopathological findings of patients with dermatochalasis and vitamin D deficiency.

التفاصيل البيبلوغرافية
العنوان: Relationship between histopathological findings of patients with dermatochalasis and vitamin D deficiency.
المؤلفون: Aydemir E; Department of Ophthalmology, Antalya City Hospital, Antalya, Turkey., Malkoç Şen E; Department of Ophthalmology, Ankara Etlik City Hospital, Ankara, Turkey., Aksoy Aydemir G; Department of Ophthalmology, Antalya City Hospital, Antalya, Turkey. gzdaksoy@hotmail.com., Bayat AH; Department of Ophthalmology, Istanbul Medipol University, Istanbul, Turkey., Karnaz A; Department of Ophthalmology, Nizip State Hospital, Gaziantep, Turkey., Aydın Türk B; Department of Pathology, Adıyaman University Education and Research Hospital, Adıyaman, Turkey.
المصدر: International ophthalmology [Int Ophthalmol] 2024 Jul 03; Vol. 44 (1), pp. 309. Date of Electronic Publication: 2024 Jul 03.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Kluwer Country of Publication: Netherlands NLM ID: 7904294 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-2630 (Electronic) Linking ISSN: 01655701 NLM ISO Abbreviation: Int Ophthalmol Subsets: MEDLINE
أسماء مطبوعة: Publication: Dordrecht : Kluwer
Original Publication: The Hague, Junk.
مواضيع طبية MeSH: Blepharoplasty*/methods , Vitamin D Deficiency*/complications , Vitamin D Deficiency*/diagnosis, Humans ; Male ; Prospective Studies ; Female ; Middle Aged ; Aged ; Eyelid Diseases/pathology ; Eyelid Diseases/diagnosis ; Adult ; Eyelids/pathology ; Vitamin D/blood
مستخلص: Purpose: To compare the histopathological findings of patients who had been diagnosed with dermatochalasis (DC) and had undergone upper eyelid blepharoplasty (ULB) as well as those of controls (C-Group) according to their serum vitamin D (SVD) levels.
Methods: The prospective study included 136 upper eyelid skin from 68 patients who underwent surgery for DC and 53 upper eyelid skin from 53 patients who underwent levator surgery with ULB. The DC Group was then divided into 3 subgroups according to the marginal reflex distance (MRD4). The lymphatic vessel (LV) count and diameter of the largest LV (DLLV) were recorded, the stromal collagen bed (SCB) was observed, and its depth was measured, the interfibrillar edema was examined, and the elastic fiber and macrophage counts and recorded, respectively, and then all of these were evaluated. The SVD levels were compared between the DC patients and the C-Group.
Results: In comparison to the C-Group, significant changes were seen in the dilated LV, DLLV, SCB depth, interfibrillar edema, elastic fiber density, and macrophage count in the DC sub-Groups (P < 0.001 for all). While no difference was found between DC sub-Group 1 (MRD4 > 4 mm) and the C-Group (P > 0.05), a significant difference was found between DC sub-Group 2 (MRD4 2-4 mm) and DC sub-Group 3 (MRD4 < 2 mm) for all of the parameters (P < 0.05). A statistically significant difference was also found in the SVD levels between the DC sub-Group 1 and DC sub-Groups 2-3 (P < 0.017, P < 0.001 respectively).
Conclusion: According to the results of this study, SVD level was significantly lower in DC group. Moreover, an increased LV count and diameter, decreased elastic fiber count, collagen fiber and stromal edema irregularity, and increased macrophage count were found to be associated with the SVD level.
(© 2024. The Author(s), under exclusive licence to Springer Nature B.V.)
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فهرسة مساهمة: Keywords: Collagen; Dermatochalasis; Elastic fiber; Histopathology; Serum vitamin D; Vitamin D deficiency
المشرفين على المادة: 1406-16-2 (Vitamin D)
تواريخ الأحداث: Date Created: 20240703 Date Completed: 20240703 Latest Revision: 20240703
رمز التحديث: 20240704
DOI: 10.1007/s10792-024-03209-3
PMID: 38960909
قاعدة البيانات: MEDLINE
الوصف
تدمد:1573-2630
DOI:10.1007/s10792-024-03209-3