دورية أكاديمية

Viral cytopathic changes in sputum cytology in a patient with known human metapneumovirus.

التفاصيل البيبلوغرافية
العنوان: Viral cytopathic changes in sputum cytology in a patient with known human metapneumovirus.
المؤلفون: Tang E, Gador-Whyte AP, Newman MR
المصدر: Acta cytologica [Acta Cytol] 2024 Jul 04. Date of Electronic Publication: 2024 Jul 04.
Publication Model: Ahead of Print
نوع المنشور: Case Reports; Journal Article
اللغة: English
بيانات الدورية: Publisher: Karger Country of Publication: Switzerland NLM ID: 0370307 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1938-2650 (Electronic) Linking ISSN: 00015547 NLM ISO Abbreviation: Acta Cytol Subsets: MEDLINE
أسماء مطبوعة: Publication: 2011- : Basel : Karger
Original Publication: Chicago : International Academy of Cytology
مستخلص: Introduction: Viral cytopathic changes seen in sputum cytology have been described in association with infection by viruses such as cytomegalovirus (CMV), herpes simplex virus (HSV), adenovirus, and even measles. However, viral cytopathic changes due to human metapneumovirus (hMPV) have not yet been well described in cytology. Human metapneumovirus is a relatively new entity, discovered in 2001. It is known to cause upper and lower respiratory tract infections in children, the elderly, and immunocompromised patients.
Case Presentation: We describe the viral cytopathic changes seen in sputum in a 63-year-old male patient with known hMPV. These changes include multinucleation, nuclear enlargement, homogenised nuclei, basophilic nuclear inclusions with perinuclear halos, and small eosinophilic cytoplasmic inclusions.
Conclusion: We aim to raise awareness that hMPV can cause viral cytopathic changes and to describe these cytological features, which have been elucidated in only one case report thus far. Distinction from other viruses with similar changes, such as HSV and CMV, is important due to their differing clinical implications.
(S. Karger AG, Basel.)
تواريخ الأحداث: Date Created: 20240704 Latest Revision: 20240704
رمز التحديث: 20240705
DOI: 10.1159/000540184
PMID: 38964304
قاعدة البيانات: MEDLINE
الوصف
تدمد:1938-2650
DOI:10.1159/000540184