دورية أكاديمية
Viral Cytopathic Changes in Sputum Cytology in a Patient with Known Human Metapneumovirus.
العنوان: | Viral Cytopathic Changes in Sputum Cytology in a Patient with Known Human Metapneumovirus. |
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المؤلفون: | Tang E; Department of Anatomical Pathology, Austin Health, Heidelberg, Victoria, Australia., Gador-Whyte AP; Department of Microbiology, Austin Health, Heidelberg, Victoria, Australia., Newman MR; Department of Anatomical Pathology, Austin Health, Heidelberg, Victoria, Australia. |
المصدر: | Acta cytologica [Acta Cytol] 2024 Jul 04, pp. 1-5. Date of Electronic Publication: 2024 Jul 04. |
Publication Model: | Ahead of Print |
نوع المنشور: | Case Reports; Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Karger Country of Publication: Switzerland NLM ID: 0370307 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1938-2650 (Electronic) Linking ISSN: 00015547 NLM ISO Abbreviation: Acta Cytol Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 2011- : Basel : Karger Original Publication: Chicago : International Academy of Cytology |
مستخلص: | Introduction: Viral cytopathic changes seen in sputum cytology have been described in association with infection by viruses such as cytomegalovirus (CMV), herpes simplex virus (HSV), adenovirus, and even measles. However, viral cytopathic changes due to human metapneumovirus (hMPV) have not yet been well described in cytology. hMPV is a relatively new entity, discovered in 2001. It is known to cause upper and lower respiratory tract infections in children, the elderly, and immunocompromised patients. Case Presentation: We describe the viral cytopathic changes seen in sputum in a 63-year-old male patient with known hMPV. These changes include multinucleation, nuclear enlargement, homogenised nuclei, basophilic nuclear inclusions with perinuclear halos, and small eosinophilic cytoplasmic inclusions. Conclusion: We aim to raise awareness that hMPV can cause viral cytopathic changes and to describe these cytological features, which have been elucidated in only 1 case report thus far. Distinction from other viruses with similar changes, such as HSV and CMV, is important due to their differing clinical implications. (© 2024 S. Karger AG, Basel.) |
فهرسة مساهمة: | Keywords: Cytopathology of infectious diseases; Human metapneumovirus; Infectious cytology |
تواريخ الأحداث: | Date Created: 20240704 Latest Revision: 20240724 |
رمز التحديث: | 20240726 |
DOI: | 10.1159/000540184 |
PMID: | 38964304 |
قاعدة البيانات: | MEDLINE |
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