دورية أكاديمية
"Rigid-Flexible" Dual-Ferrocene Chimeric Nanonetwork for Simultaneous Tumor-Targeted Tracing and Photothermal/Photodynamic Therapy.
العنوان: | "Rigid-Flexible" Dual-Ferrocene Chimeric Nanonetwork for Simultaneous Tumor-Targeted Tracing and Photothermal/Photodynamic Therapy. |
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المؤلفون: | Wang S; School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, P. R. China., Zhang R; School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, P. R. China., Li X; School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, P. R. China., Chen Y; School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, P. R. China., Zhu L; School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, P. R. China., Yang B; School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, P. R. China., Wang J; School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, P. R. China., Du YH; School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, P. R. China., Liu J; Wuya College of Innovation, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, P. R. China., Ye TT; School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, P. R. China., Wang S; School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, P. R. China. |
المصدر: | ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2024 Jul 17; Vol. 16 (28), pp. 36142-36156. Date of Electronic Publication: 2024 Jul 05. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 101504991 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1944-8252 (Electronic) Linking ISSN: 19448244 NLM ISO Abbreviation: ACS Appl Mater Interfaces Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Washington, D.C. : American Chemical Society |
مواضيع طبية MeSH: | Ferrous Compounds*/chemistry , Photochemotherapy* , Metallocenes*/chemistry , Indocyanine Green*/chemistry , Indocyanine Green*/therapeutic use , Indocyanine Green*/pharmacology , Hyaluronic Acid*/chemistry, Humans ; Animals ; Mice ; Photothermal Therapy ; Female ; Fluorescent Dyes/chemistry ; Fluorescent Dyes/pharmacology ; Mice, Inbred BALB C ; Photosensitizing Agents/chemistry ; Photosensitizing Agents/pharmacology ; Photosensitizing Agents/therapeutic use ; Mice, Nude ; Cell Line, Tumor ; Neoplasms/diagnostic imaging ; Neoplasms/drug therapy ; Neoplasms/therapy ; Neoplasms/pathology ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Nanoparticles/chemistry ; Nanoparticles/therapeutic use |
مستخلص: | There is an urgent need to develop phototherapeutic agents with imaging capabilities to assess the treatment process and efficacy in real-time during cancer phototherapy for precision cancer therapy. The safe near-infrared (NIR) fluorescent dyes have garnered significant attention and are desirable for theranostics agents. However, until now, achieving excellent photostability and fluorescence (FL) imaging capability in aggregation-caused quenching (ACQ) dyes remains a big challenge. Here, for the only FDA-approved NIR dye, indocyanine green (ICG), we developed a dual-ferrocene (Fc) chimeric nanonetwork ICG@HFFC based on the rigid-flexible strategy through one-step self-assembly, which uses rigid Fc-modified hyaluronic acid (HA) copolymer (HA-Fc) and flexible octadecylamine (ODA) bonded Fc (Fc-C |
فهرسة مساهمة: | Keywords: aggregation-caused quenching (ACQ); ferrocene (Fc); indocyanine green (ICG); rigid-flexible; tumor visualization therapy |
المشرفين على المادة: | 0 (Ferrous Compounds) 0 (Metallocenes) U96PKG90JQ (ferrocene) IX6J1063HV (Indocyanine Green) 9004-61-9 (Hyaluronic Acid) 0 (Fluorescent Dyes) 0 (Photosensitizing Agents) 0 (Antineoplastic Agents) |
تواريخ الأحداث: | Date Created: 20240705 Date Completed: 20240718 Latest Revision: 20240718 |
رمز التحديث: | 20240718 |
DOI: | 10.1021/acsami.4c06437 |
PMID: | 38968001 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1944-8252 |
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DOI: | 10.1021/acsami.4c06437 |