دورية أكاديمية
Placental pathology lesions: International Society for Ultrasound in Obstetrics and Gynecology vs Society for Maternal-Fetal Medicine fetal growth restriction definitions.
| العنوان: | Placental pathology lesions: International Society for Ultrasound in Obstetrics and Gynecology vs Society for Maternal-Fetal Medicine fetal growth restriction definitions. |
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| المؤلفون: | Rodriguez-Sibaja MJ; Maternal-Fetal Medicine Division, Instituto Nacional de Perinatologia, Mexico City, Mexico (Rodriguez-Sibaja, Lopez-Diaz, Acevedo-Gallegos, Amaya-Guel, Camarena-Cabrera, and Lumbreras-Marquez)., Lopez-Diaz AJ; Maternal-Fetal Medicine Division, Instituto Nacional de Perinatologia, Mexico City, Mexico (Rodriguez-Sibaja, Lopez-Diaz, Acevedo-Gallegos, Amaya-Guel, Camarena-Cabrera, and Lumbreras-Marquez)., Valdespino-Vazquez MY; Pathology Division, Instituto Nacional de Perinatologia, Mexico City, Mexico (Valdespino-Vazquez)., Acevedo-Gallegos S; Maternal-Fetal Medicine Division, Instituto Nacional de Perinatologia, Mexico City, Mexico (Rodriguez-Sibaja, Lopez-Diaz, Acevedo-Gallegos, Amaya-Guel, Camarena-Cabrera, and Lumbreras-Marquez)., Amaya-Guel Y; Maternal-Fetal Medicine Division, Instituto Nacional de Perinatologia, Mexico City, Mexico (Rodriguez-Sibaja, Lopez-Diaz, Acevedo-Gallegos, Amaya-Guel, Camarena-Cabrera, and Lumbreras-Marquez)., Camarena-Cabrera DM; Maternal-Fetal Medicine Division, Instituto Nacional de Perinatologia, Mexico City, Mexico (Rodriguez-Sibaja, Lopez-Diaz, Acevedo-Gallegos, Amaya-Guel, Camarena-Cabrera, and Lumbreras-Marquez)., Lumbreras-Marquez MI; Maternal-Fetal Medicine Division, Instituto Nacional de Perinatologia, Mexico City, Mexico (Rodriguez-Sibaja, Lopez-Diaz, Acevedo-Gallegos, Amaya-Guel, Camarena-Cabrera, and Lumbreras-Marquez); Department of Epidemiology and Public Health, Universidad Panamericana School of Medicine, Mexico City, Mexico (Lumbreras-Marquez). Electronic address: mario.lumbreras@inper.gob.mx. |
| المصدر: | American journal of obstetrics & gynecology MFM [Am J Obstet Gynecol MFM] 2024 Jul 03; Vol. 6 (8), pp. 101422. Date of Electronic Publication: 2024 Jul 03. |
| Publication Model: | Ahead of Print |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101746609 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2589-9333 (Electronic) Linking ISSN: 25899333 NLM ISO Abbreviation: Am J Obstet Gynecol MFM Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: [New York, NY] : Elsevier Inc., [2019]- |
| مستخلص: | Background: Research on the definition of fetal growth restriction (FGR) has focused on predicting adverse perinatal outcomes. A significant limitation of this approach is that the individual outcomes of interest could be related to the condition and the treatment. Evaluation of outcomes that reflect the pathophysiology of FGR may overcome this limitation. Objective: To compare the diagnostic performance of the FGR definitions established by the International Society for Ultrasound in Obstetrics and Gynecology (ISUOG) and the Society for Maternal-Fetal Medicine (SMFM) to predict placental histopathological findings associated with placental insufficiency and a composite adverse neonatal outcome (ANeO). Study Design: In this retrospective cohort study of singleton pregnancies, the ISUOG and the SMFM guidelines were used to identify pregnancies with FGR and a corresponding control group. The primary outcome was the prediction of placental histopathological findings associated with placental insufficiency, defined as lesions associated with maternal vascular malperfusion (MVM). A composite ANeO (ie, umbilical artery pH≤7.1, Apgar score at 5 minutes ≤4, neonatal intensive care unit admission, hypoglycemia, respiratory distress syndrome requiring mechanical ventilation, intrapartum fetal distress requiring expedited delivery, and perinatal death) was investigated as a secondary outcome. Sensitivity, specificity, positive and negative predictive values, and the areas under the receiver-operating-characteristics curves were determined for each FGR definition. Logistic regression models were used to assess the association between each definition and the studied outcomes. A subgroup analysis of the diagnostic performance of both definitions stratifying the population in early and late FGR was also performed. Results: Both societies' definitions showed a similar diagnostic performance as well as a significant association with the primary (ISUOG adjusted odds ratio 3.01 [95% confidence interval 2.42, 3.75]; SMFM adjusted odds ratio 2.85 [95% confidence interval 2.31, 3.51]) and secondary outcomes (ISUOG adjusted odds ratio 1.95 [95% confidence interval 1.56, 2.43]; SMFM adjusted odds ratio 2.12 [95% confidence interval 1.70, 2.65]). Furthermore, both FGR definitions had a limited discriminatory capacity for placental histopathological findings of MVM and the composite ANeO (area under the receiver-operating-characteristics curve ISUOG 0.63 [95% confidence interval 0.61, 0.65], 0.59 [95% confidence interval 0.56, 0.61]; area under the receiver-operating-characteristics SMFM 0.63 [95% confidence interval 0.61, 0.66], 0.60 [95% confidence interval 0.57, 0.62]). Conclusion: The ISUOG and the SMFM FGR definitions have limited discriminatory capacity for placental histopathological findings associated with placental insufficiency and a composite ANeO. (Copyright © 2024 The Author(s). Published by Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Doppler; fetal growth; fetal growth restriction; maternal vascular malperfusion; placenta; placental insufficiency; placental lesions; placental pathology; small for gestational age; ultrasound |
| تواريخ الأحداث: | Date Created: 20240705 Latest Revision: 20240725 |
| رمز التحديث: | 20240726 |
| DOI: | 10.1016/j.ajogmf.2024.101422 |
| PMID: | 38969177 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 2589-9333 |
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| DOI: | 10.1016/j.ajogmf.2024.101422 |